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Effects of GLPG3970 on Sulfasalazine and Methotrexate Pharmacokinetics in Healthy Adults: Two Open‐Label, Phase I, Drug–Drug Interaction Studies2024 Clinical Pharmacology & Therapeutics article Medicine Drug Transport and Resistance Mechanisms Open access
Mariska C. van der Plas, Volha Zabela, Fien Gistelinck, Susan Bellaire
3citations -
What the Product Label Does Not Tell You About Drug–Drug Interaction Management2023 The Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacy and Medical Practices Open access
David Marinus Burger, Marianne le Comte, Elise Joëlle Smolders, Tom G. Jacobs, Rob ter Heine, Catherijne A. J. Knibbe, +1 more
8citations -
Benefit‐Risk Assessment of Off‐Label Drug Use in Children: The Bravo Framework2021 Clinical Pharmacology & Therapeutics article Medicine Pharmaceutical studies and practices Open access
Tjitske M. van der Zanden, Miriam G. Mooij, Nienke J. Vet, Antje C. Neubert, Wolfgang Rascher, Florian B. Lagler, +5 more
63citations -
Monitoring Anthracycline Cancer Drug‐Nucleosome Interaction by NMR Using a Specific Isotope Labeling Approach for Nucleosomal DNA2024 ChemBioChem article Biochemistry, Genetics and Molecular Biology DNA and Nucleic Acid Chemistry Open access
Clara L. van Emmerik, Vincenzo R. Lobbia, Jacques Neefjes, Frank H. T. Nelissen, Hugo van Ingen
3citations -
Impact of changing open-label drug prescription policies on consent rates in a neonatal trial: a quasinatural experiment2026 Archives of Disease in Childhood Fetal & Neonatal article Medicine Ethics in Clinical Research Open access
Kelly K. Storm, Robert B. Flint, Wes Onland, Sylvia A Obermann-Borst, Jarinda A. Poppe, Debbie H. G. M. Nuytemans, +23 more
0citations -
Effects of tapering conventional synthetic disease-modifying antirheumatic drugs to drug-free remission versus stable treatment in rheumatoid arthritis (ARCTIC REWIND): 3-year results from an open-label, randomised controlled, non-inferiority trial2024 The Lancet Rheumatology article Medicine Rheumatoid Arthritis Research and Therapies Open access
Kaja E Kjørholt, Nina Paulshus Sundlisæter, Anna‐Birgitte Aga, Joseph Sexton, Inge Christoffer Olsen, Hallvard Fremstad, +16 more
17citations -
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study2023 The Lancet article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jesse Joachim Swen, Cathelijne H. van der Wouden, Lisanne E. N. Manson, H. Abdullah-Koolmees, Kathrin Blagec, Tanja Blagus, +92 more
553citations -
Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One‐Year Results of a Double‐Blind, Placebo‐Controlled Study and Open‐Label Extension
Atul A. Deodhar, Désirée M F M van der Heijde, Joachim Sieper, Filip E Van den Bosch, Walter P. Maksymowych, Tae‐Hwan Kim, +6 more
66citations -
Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake2023 Nanomedicine Nanotechnology Biology and Medicine article Materials Science Nanoparticle-Based Drug Delivery
Sarah Schraven, Stefanie Rosenhain, Ramona Brueck, Tim Marvin Wiechmann, Robert Pola, Tomáš Etrych, +4 more
7citations -
A systematic review on disease‐drug‐drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labelling2022 British Journal of Clinical Pharmacology review Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Laura M. de Jong, Sylvia D. Klomp, Nicoline Treijtel, Robert Rißmann, Jesse Joachim Swen, Martijn L. Manson
8citations -
Zervixreifung nach Kaiserschnitt: Prospektive Multicenter „in-label use“ Analyse eines osmotischen Dilatators vs. „off-label use“ Prostaglandin PGE22020 Zeitschrift für Geburtshilfe und Neonatologie conference-paper Medicine Maternal and Perinatal Health Interventions
J Maier, S Klauke, K Brandt, JP Scharf, Ute Jarchau, Elisabeth Schalinski, +2 more
0citations -
Impact of a Bundle of Interventions on the Spectrum of Parenteral Drug Preparation Errors in a Neonatal and Pediatric Intensive Care Unit2024 Journal of Clinical Medicine article Health Professions Patient Safety and Medication Errors Open access
Sabine von Hobe, Mark Schoberer, Thorsten W Orlikowsky, Nina Kusch, Albrecht Eisert
2citations -
Prospective evaluation of genomics-guided off-label treatment2026 Nature article Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
A C Spiekman, Soemeya F. Haj Mohammad, Florentine A.J. Verbeek, Hans J.L. Timmer, Maud A. van Maren, Laurien Joanna Zeverijn, +42 more
9citations -
Descriptive analysis of adverse drug reaction reports in children and adolescents from Germany: frequently reported reactions and suspected drugs2021 BMC Pharmacology and Toxicology article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
Diana Dubrall, Sarah Leitzen, Irmgard Toni, Julia Stingl, Maike Schulz, Matthias C. Schmid, +2 more
22citations -
Analysis of the reporting of adverse drug reactions in children and adolescents in Germany in the time period from 2000 to 20192021 PLoS ONE article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
Sarah Leitzen, Diana Dubrall, Irmgard Toni, Julia Stingl, Maike Schulz, Matthias C. Schmid, +2 more
25citations -
Excited‐State Basicity Diverts the Site‐Selectivity of Aromatic Deuteration: Application to the Late‐Stage Labeling of Pharmaceuticals2025 Angewandte Chemie International Edition article Pharmacology, Toxicology and Pharmaceutics Chemical Reactions and Isotopes Open access
Eva Rivera‐Chao, Javier Corpas, Giovanni Lonardi, Volker Derdau, Alessandro Ruffoni, Daniele Leonori
6citations -
An Update on the Use of Allometric and Other Scaling Methods to Scale Drug Clearance in Children: Towards Decision Tables2022 Expert Opinion on Drug Metabolism & Toxicology article Medicine Pharmaceutical studies and practices Open access cited by 1 patent
Anne van Rongen, Elke H. J. Krekels, Elisa A. M. Calvier, Saskia N. de Wildt, An Vermeulen, Catherijne A. J. Knibbe
32citations -
Effect of Roxadustat on the Pharmacokinetics of Simvastatin, Rosuvastatin, and Atorvastatin in Healthy Subjects: Results From 3 Phase 1, Open‐Label, 1‐Sequence, Crossover Studies2022 Clinical Pharmacology in Drug Development article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Dorien Groenendaal‐van de Meent, Martin den Adel, Virginie Kerbusch, Tomohisa Shibata, Kota Kato, Marloes P. Schaddelee
13citations -
How do others cope? Extracting coping strategies for adverse drug events from social media2022 Journal of Biomedical Informatics article Biochemistry, Genetics and Molecular Biology Biomedical Text Mining and Ontologies Open access
Anne R. Dirkson, Suzan Verberne, G. van Oortmerssen, Hans A. J. Gelderblom, Wessel Kraaij
8citations