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Study protocol of the HD-MED study aiming to personalize drug treatment in Huntington’s disease: a longitudinal, observational study to assess medication use and efficacy in relation to pharmacogenetics2023 Therapeutic Advances in Rare Disease article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Stephanie Feleus, Maaike van der Lee, Jesse Joachim Swen, Raymund A.C. Roos, Susanne Tamara de Bot
2citations -
VAE-MOTION: A deep generative model for cardiomyocyte contractility analysis for improving drug efficacy evaluation2025 Expert Systems with Applications article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Giorgia Curci, Paola Casti, Luca Sala, Marcella Brescia, Pasquale Cascarano, Michele D’Orazio, +6 more
1citations -
Inhibition of SUMOylation enhances DNA hypomethylating drug efficacy to reduce outgrowth of hematopoietic malignancies2023 Leukemia article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 2 patents
Jessie S. Kroonen, Ilona J. de Graaf, Sumit Kumar, Dennis F.G. Remst, Anne K. Wouters, Mirjam H.M. Heemskerk, +1 more
22citations -
Role of DNA-detection–based tools for monitoring the soil-transmitted helminth treatment response in drug-efficacy trials2020 PLoS neglected tropical diseases article Immunology and Microbiology Parasites and Host Interactions Open access
Javier Gandasegui, María Martínez Valladares, Berta Grau-Pujol, Alejandro Javier Krolewiecki, Rafael Balaña‐Fouce, Woyneshet Gelaye, +4 more
24citations -
Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One‐Year Results of a Double‐Blind, Placebo‐Controlled Study and Open‐Label Extension
Atul A. Deodhar, Désirée M F M van der Heijde, Joachim Sieper, Filip E Van den Bosch, Walter P. Maksymowych, Tae‐Hwan Kim, +6 more
66citations -
Efficacy of Pembrolizumab and Biomarker Analysis in Patients with WGS-Based Intermediate to High Tumor Mutational Load: Results from the Drug Rediscovery Protocol
Birgit S. Geurts, Laurien Joanna Zeverijn, Lindsay V.M. Leek, Jade M. van Berge Henegouwen, Louisa Rose Hoes, Hanneke van der Wijngaart, +15 more
4citations -
Efficacy and safety of panitumumab in patients with RAF/RAS-wild-type glioblastoma: results from the drug rediscovery protocol2023 Leiden Repository (Leiden University) article Medicine Glioma Diagnosis and Treatment Open access
I.A.C. Spiekman, B.S. Geurts, L.J. Zeverijn, G.F. de Wit, V. van der Noort, P. Roepman, +12 more
0citations -
Addendum To: Study protocol of the HD-MED study aiming to personalize drug treatment in Huntington’s disease: a longitudinal, observational study to assess medication use and efficacy in relation to pharmacogenetics2024 Therapeutic Advances in Rare Disease article Neuroscience Genetic Neurodegenerative Diseases Open access
Stephanie Feleus, Maaike van der Lee, Jesse Joachim Swen, Raymund A.C. Roos, Susanne Tamara de Bot
1citations -
257P Efficacy of pembrolizumab in pre-treated breast cancer harboring high mutational load 140-290 – results from the Drug Rediscovery Protocol (DRUP)
Laurien Joanna Zeverijn, Birgit S. Geurts, Jade M. van Berge Henegouwen, Louisa Rose Hoes, Hanneke van der Wijngaart, G.F. de Wit, +8 more
0citations -
#2028 Efficacy and safety of sucroferric oxyhydroxide versus sevelamer carbonate: a systematic review and meta-analysis2024 Nephrology Dialysis Transplantation article Medicine Parathyroid Disorders and Treatments Open access
Christos Georgopoulos, Αnila Duni, Eleni Stamellou, Αθανάσιος Κίτσος, Charikleia Gouva, Evangelia Ntounousi
1citations -
Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults – a pilot randomized, double-blind, placebo-controlled single-centre phase Ib/IIa clinical trial
Dorothea Ekoka Mbassi, Ghyslain Mombo‐Ngoma, Jana Held, Dearie Glory Okwu, Wilfrid Ndzebe Ndoumba, Laura C Kalkman, +11 more
10citations -
Update on the Efficacy and Safety Profile of Voclosporin: An Integrated Analysis of Clinical Trials in Lupus Nephritis2022 Arthritis Care & Research article Medicine Systemic Lupus Erythematosus Research Open access cited by 1 patent
Cristina Arriens, Y K Onno Teng, Ellen M. Ginzler, Samir V. Parikh, Anca Askanase, Amit Saxena, +8 more
46citations -
Ambroxol for the treatment of children with acute and chronic respiratory diseases: an overview of efficacy and safety2020 Multidisciplinary Respiratory Medicine article Medicine Respiratory and Cough-Related Research Open access
Ahmad Kantar, Ludger Klimek, Dorotheea Cazan, Annette Sperl, Ulrike Sent
40citations -
Efficacy and Safety of TAK-861, an Oral Orexin Receptor 2 Agonist, in Individuals with Narcolepsy Type 1: Results from a Phase 2 Trial and Long-Term Extension Study Interim Analysis (P12-4.002)
Yves A Dauvilliers, Emmanuel Mignot, Giuseppe Plazzi, Gert Jan Lammers, Harisha Kadali, Ellie Stukalin, +6 more
1citations -
Efficacy of pharmacological treatment in rheumatoid arthritis: a systematic literature research informing the 2019 update of the EULAR recommendations for management of rheumatoid arthritis2020 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Andreas Kerschbaumer, Alexandre Rocha Sepriano, Josef S Smolen, Désirée M F M van der Heijde, Maxime Dougados, Ronald van Vollenhoven, +6 more
292citations