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Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Thomas Geuens, Floor A.A. Ruiter, Anika Schumacher, Francis L. C. Morgan, Timo Rademakers, Loes E. Wiersma, +4 more
1citations -
Matrix stiffness affects spheroid invasion, collagen remodeling and the effective reach of stress into the ECM2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions
Klara Beslmüller, Rick Rodrigues de Mercado, Gijsje Hendrika Koenderink, Erik H.J. Danen, Thomas Schmidt
2citations -
Inter-Spheroid Proximity and Matrix Remodeling Determine CAF-Mediated Cancer Cell Invasion2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Pranav Mehta, Ankur Bordoloi, Cor J. Ravensbergen, M. Kristen David, Wilma E. Mesker, Gerrit‐Jan Liefers, +2 more
1citations -
How cells align to structured collagen fibrils: A hybrid cellular Potts and molecular dynamics model with dynamic mechanosensitive focal adhesions1citations
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EMT-dependent cell-matrix interactions are linked to unjamming transitions in cancer spheroid invasion2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Anouk van der Net, Ankur Bordoloi, Iain Muntz, Peter ten Dijke, Pouyan E. Boukany, Gijsje Hendrika Koenderink
3citations -
Data-driven traction force microscopy in 3D collagen hydrogels2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Jorge Barrasa Fano, Laurens Kimps, Alejandro Apolinar–Fernández, Débora do Carmo Linhares, Iain Muntz, Elías Núñez-Ortega, +6 more
0citations -
Distinct Effects of the Extracellular Matrix on Tumor Organization and Response to Cancer Virotherapy2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Frederique Visscher, Annemarie Boerma, Anne K. Wouters, Manas Joshi, Mirjam H.M. Heemskerk, Darshak Bhatt
0citations -
Invasive cancer cells soften collagen networks and disrupt stress-stiffening via volume exclusion, contractility and adhesion2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Irène Nagle, Margherita Tavasso, Ankur Bordoloi, Iain Muntz, Gijsje Hendrika Koenderink, Pouyan E. Boukany
1citations -
Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Harry M. Warner, Giulia Franciosa, Guus van der Borg, Felix Faas, Claire Koenig, Rinse de Boer, +13 more
1citations -
Patterned alginate hydrogel spatially guides collagen fibrillogenesis, viscoelasticity and endothelial cell invasion2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Hydrogels: synthesis, properties, applications Open access
Claudia A. Garrido, Daniela S. Garske, Bernhard Häßel, C Bastard, Julia van de Kamp, Laura De Laporte, +3 more
0citations -
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, David P. Sumpton, Claudia Boldrini, Juan Ramon Hernandez-Fernaud, Sandeep Dhayade, +18 more
6citations -
Myogenic Differentiation of Human Myoblasts and Mesenchymal Stromal Stem Cells under GDF11 on Poly-ɛ-Caprolactone-Collagen I-Polyethylene-Nanofibers2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Aijia Cai, Zengming Zheng, Justus P. Beier, Marcus Himmler, Dirk Wolfram Schubert, Volker Weisbach, +2 more
6citations -
Septins promote breast cancer cell invasion in 3D collagen gels by influencing actin-based protrusion formation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Anouk van der Net, Klara Beslmüller, Nicole van Vliet, Margherita Tavasso, Myrthe Beerens, Ruben C. Boot, +3 more
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A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Osteoarthritis Treatment and Mechanisms Open access
Niek G.C. Bloks, Zainab Harissa, Shaunak Sanjay Adkar, Amanda R. Dicks, Ghazaleh Hajmousa, Nancy S. Steward, +8 more
2citations -
Altered Mechanobiology of PDAC Cells with Acquired Chemoresistance to Gemcitabine and Paclitaxel2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Alessandro Gregori, Cecilia Bergonzini, Mjriam Capula, Rick Rodrigues de Mercado, Erik H.J. Danen, Elisa Giovannetti, +1 more
1citations -
Secretome analysis of human and rat pancreatic islets co-cultured with adipose-derived stromal cells reveals a signature with enhanced regenerative capacities2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Erika Pinheiro-Machado, Bart J. de Haan, Marten A. Engelse, Alexandra M. Smink
0citations -
Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chen‐Yi Liao, Jasmijn H.M. Hundscheid, Justin Crawford, Peter ten Dijke, Beatrice Coorneaert, Erik H.J. Danen
0citations -
Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chronic Kidney Disease and Diabetes Open access
Nadine Tuechler, Mira Lea Burtscher, Martín Garrido‐Rodríguez, Muzamil Majid Khan, Dénes Türei, Christian Tischer, +8 more
0citations