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Single-cell transcriptomics in bone marrow delineates CD56dimGranzymeK+ subset as intermediate stage in NK cell differentiation2022 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Monique M. van Ostaijen-ten Dam, Dorenda J. A. Schoorl, Pieter J. Schol, Daphne A. L. van den Homberg, Arjan C. Lankester, +2 more
18citations -
PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories2025 Nature Methods article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Mingbo Cheng, Jitske Jansen, Katharina C. Reimer, Vincent P. Grande, James Shiniti Nagai, Zhijian Li, +6 more
9citations -
Trypanosoma cruzi cell atlas as a single-cell resource for understanding parasite population heterogeneity and differentiation2026 Nature Communications article Medicine Trypanosoma species research and implications Open access
Ross F Laidlaw, Marta García-Sánchez, Juliana da Silva Pacheco, Luciana S. Paradela, Thomas D. Otto, Manu De Rycker
2citations -
Cell Cluster Sorting in Automated Differentiation of Patient-specific Induced Pluripotent Stem Cells Towards Blood Cells2022 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Zhiyao Ma, Marcelo Augusto Szymanskide Toledo, Paul Wanek, Mohamed H. Elsafi Mabrouk, Rock Pulak, Simon Pieske, +6 more
11citations -
Tissue of Origin, but Not XCI State, Influences Germ Cell Differentiation from Human Pluripotent Stem Cells2021 Cells article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Arend W. Overeem, Celine M. Roelse, Xueying Fan, Susana M. Chuva de Sousa Lopes
10citations -
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation2021 EMBO Reports article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Muhammad Assad Aslam, Mir Farshid Alemdehy, Eliza Mari Kwesi‐Maliepaard, Marieta Cagánová, Iris N. Pardieck, Teun van den Brand, +9 more
54citations -
Stem-like PD-1 + TCF-1 + CD8 + T cells result from helpless priming and rely on CD4 + T-cell help to complete their cytotoxic effector differentiation2026 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology T-cell and B-cell Immunology Open access
Julia Busselaar, Douwe M. T. Bosma, Mo D. Staal, Xin Lei, Yanling Xiao, Jannie G. Borst
2citations -
Comment to: Single-cell profiling reveals the trajectories of natural killer cell differentiation in bone marrow and a stress signature induced by acute myeloid leukemia2021 Cellular and Molecular Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Janine E. Melsen, Gertjan Lugthart, Monique M. van Ostaijen-ten Dam, Marco W. Schilham
6citations -
CD4+ T-cell help delivery to monocyte-derived dendritic cells promotes effector differentiation of helper and cytotoxic T cells2025 Immunology Letters article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Douwe M. T. Bosma, Julia Busselaar, Mo D. Staal, Elselien Frijlink, Matthias Mack, Fiamma Salerno, +1 more
7citations -
USP18 is an essential regulator of muscle cell differentiation and maturation2023 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Cyriel Sebastiaan Olie, Adán Pinto-Fernández, Andreas Damianou, Iolanda Vendrell, Hailiang Mei, Bianca den Hamer, +4 more
20citations -
Effects of single and repeated shock wave application on the osteogenic differentiation potential of human primary mesenchymal stromal cells and the osteoblastic cell line MG63 in vitro2023 Frontiers in Bioengineering and Biotechnology article Medicine Tendon Structure and Treatment Open access
El-Mustapha Haddouti, Nina Reinhardt, Robert Ossendorff, C. Burger, Dieter Christian Wirtz, Matias de la Fuente, +1 more
1citations -
Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation2022 Cell stem cell article Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access
Gangqi Wang, Bram Heijs, Sarantos Kostidis, Rosalie G. J. Rietjens, Marije Koning, Lushun Yuan, +9 more
128citations -
High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype2022 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Di Wang, Katarina Madunić, Tao Zhang, Oleg A. Mayboroda, Guinevere S. M. Lageveen‐Kammeijer, Manfred Wuhrer
25citations -
Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity2023 Cellular and Molecular Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte‐Real, Ibrahim Hamad, Sam Vanherle, +16 more
65citations -
Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy E. van den Akker, David G.P. van IJzendoorn, Harald M. M. Mikkers, +5 more
3citations -
Schwann Cell-Derived Exosomes Induce the Differentiation of Human Adipose-Derived Stem Cells Into Schwann Cells2022 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Nan Zhou, Xu Zhao, Xiang Li, Sen Ren, Jing Chen, Hewei Xiong, +8 more
20citations -
The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation2021 Frontiers in Immunology article Immunology and Microbiology Psoriasis: Treatment and Pathogenesis Open access
Lisa Sandner, Marlis Alteneder, Ci Zhu, Anastasiya Hladik, Sandra Högler, Ramona Rîca, +8 more
13citations -
A lncRNA identifies Irf8 enhancer element in negative feedback control of dendritic cell differentiation2023 eLife article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Huaming Xu, Zhijian Li, Chao‐Chung Kuo, Katrin Götz, Thomas A. Look, Marcelo AS de Toledo, +3 more
14citations -
Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype2020 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Katarina Madunić, Tao Zhang, Oleg A. Mayboroda, Stephanie Holst, Kathrin Stavenhagen, Chunsheng Jin, +3 more
67citations