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Single-cell immune profiling reveals novel thymus-seeding populations, T cell commitment, and multi-lineage development in the human thymus2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Martijn Cordes, Kirsten Canté-Barrett, Erik B. van den Akker, Federico A. Moretti, Szymon M. Kiełbasa, Sandra A. Vloemans, +6 more
5citations -
Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Hiranmayi Ravichandran, André F. Rendeiro, Aharon G. Freud, Bethany L. Mundy-Bosse, +8 more
5citations -
Mapping human natural killer cell development in tonsil2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Ansel P. Nalin, Hiranmayi Ravichandran, André F. Rendeiro, Bethany L. Mundy-Bosse, +9 more
1citations -
Tviblindi algorithm identifies branching developmental trajectories of human B cell development2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Marina Bakardjieva, Jan Stuchlý, Ondřej Pelák, Marjolein W. J. Wentink, Hana Glier, David Novák, +6 more
1citations -
Cell-type, single-cell, and spatial signatures of brain-region specific splicing in postnatal development2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Anoushka Joglekar, Andrey D. Prjibelski, Ahmed Essam Mahfouz, Paul G. Collier, Susan Lin, Anna Katharina Schlusche, +22 more
5citations -
The epigenetic reader MORC3 is required for T cell development in the thymus2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology
Veronica Della Chiara, Maja Vukić, Jihed Chouaref, Laura García-Pérez, Gita Naber, Kelly K. D. Vonk, +9 more
0citations -
Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myasthenia Gravis and Thymoma Open access
Laurent M. Paardekooper, Yvonne E. Fillié‐Grijpma, Alita J. van der Sluijs‐Gelling, Mihaela Zlei, Remco van Doorn, Maarten H. Vermeer, +6 more
0citations -
Zygotene cilia regulate meiosis, germ cell development and fertility in zebrafish, mice, and humans2025 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Yaniv M. Elkouby, Xuelian Sun, Avishag Mytlis, Sylwia M. Czukiewska, Brigite Cabrita, Mengmeng Ge, +16 more
0citations -
Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Xingfan Huang, Jana Henck, Chengxiang Qiu, Varun K. A. Sreenivasan, Saranya Balachandran, Rose Yinghan Behncke, +27 more
5citations -
YAP1 Contributes to The Development of Contractile Force and Sarcomere Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Vladimír Vinarský, Stefania Pagliari, Cristina Mazzotti, Katerina Jirakova, Zuzana Garlíková, Enrico Di Iuri, +9 more
1citations -
Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Alexandra de la Porte, Julia Schröder, Moritz Thomas, Johanna Geuder, Michael Sterr, Leslie E. Sanderson, +5 more
1citations -
Single-Cell Roadmap of Early Hemato-Endothelial Development: Functions of Atf3, Zfp711 and Bcl6b2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Hematopoietic Stem Cell Transplantation Open access
Rıdvan Çeti̇n, Giulia Picco, Jente van Staalduinen, Eric M. Bindels, Remco Michiel Hoogenboezem, Gregory van Beek, +7 more
0citations -
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Jan Pascal Kahler, Damiano Arella, Cherina Lin, Willem Jespers, Sebastian J. Pomplun
1citations -
Reconstitution of human fetal ovaries reveals niche requirements for primordial germ cell-like cell progression2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Albert Blanch-Asensio, Arend W. Overeem, Susana M. Chuva de Sousa Lopes
2citations -
RFX3 is essential for the development and maturation of human pancreatic islets derived from pluripotent stem cells2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Bushra Memon, Noura Aldous, Ahmed K. Elsayed, Sadaf Ijaz, Sikander Hayat, Essam Mohamed Abdelalim
0citations -
Enhanced cell wall mechanics in VirtualLeaf enable realistic simulations of plant tissue dynamics2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Polysaccharides and Plant Cell Walls Open access
Richard W. van Nieuwenhoven, Bruno Hay Mele, Roeland M. H. Merks, Ruth Großeholz
0citations -
Embryonic nutritional hyperglycemia decreases cell proliferation in the zebrafish retina2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Ismael Hernández‐Núñez, María Vivero-Lopez, Ana Quelle‐Regaldie, Willem J. DeGrip, Laura E. Sanchez, Ángel Concheiro, +3 more
0citations -
Loss of ABCA4 from photoreceptor discs triggers changes in glial cell homeostasis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Rossella Valenzano, Andrew J. McDonald, Carmen Gallego, Charlotte A. Andriessen, Ioannis Moustakas, Aat A. Mulder, +4 more
0citations -
Mapping the regulatory wiring of endothelial cell differentiation reveals a critical role for Hippo mechanosignaling2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Hippo pathway signaling and YAP/TAZ Open access
Tri C. Nguyen, Hunter D. King, Dulguun Amgalan, Olga Pushkarev, Yanyan Alexandra Mo, Chad J. Munger, +20 more
0citations -
SIRV: Spatial inference of RNA velocity at the single-cell resolution2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Tamim Abdelaal, Laurens M. Grossouw, R. Jeroen Pasterkamp, Boudewijn P. F. Lelieveldt, Marcel J. T. Reinders, Ahmed Essam Mahfouz
12citations -
FOXP1 differentially regulates the development of murine vasopressin and oxytocin magnocellular neurons2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroendocrine regulation and behavior Open access
Jari B. Berkhout, Sophie Trender, Quirin Krabichler, Yuval Podpecan, Felix Franke, J. Peter H. Burbach, +6 more
0citations -
Characterization of the human fetal rete region by single cell transcriptional analysis of gonads and mesonephros/epididymis2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Sperm and Testicular Function Open access
Jasin Taelman, Sylwia M. Czukiewska, Ioannis Moustakas, Yolanda W. Chang, Sanne Hillenius, Talia van der Helm, +3 more
8citations