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A Network-based Transcriptomic Landscape of HepG2 cells to Uncover Causal Gene Cytotoxicity Interactions Underlying Drug-Induced Liver Injury2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Lukas S. Wijaya, Attila Gábor, Iris Pot, Luca van de Have, Julio Sáez-Rodríguez, James L. Stevens, +3 more
1citations -
Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida L. Surakka, Shweta Ramdas, Xiang Zhu, +91 more
8citations -
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Aurélien J. F. Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Kristina Bennet Emdal, Dorte B. Bekker‐Jensen, +7 more
16citations -
Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals2025 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Mengyu Zhang, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Raymond Noordam, Pavithra Nagarajan, +89 more
0citations -
Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Panuwat Trairatphisan, Terezinha Maria de Souza, Jos C. S. Kleinjans, Danyel G. J. Jennen, Julio Sáez-Rodríguez
0citations -
The role of gene expression on human sexual dimorphism: too early to call2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Eleonora Porcu, Annique Claringbould, Kaido Lepik, Tom G. Richardson, Federico Andrea Santoni, Lude Franke, +2 more
3citations -
A stepwise short- and long-read whole genome sequencing strategy resolves previous genetically unresolved inherited retinal disease cases2026 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access
Kim Rodenburg, Stefanida Shliaga, Lonneke Haer‐Wigman, Anneke T. Vulto‐van Silfhout, Erica G. M. Boonen, Lara K. Holtes, +24 more
0citations -
Genome-wide characterization of circulating metabolic biomarkers reveals substantial pleiotropy and novel disease pathways2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Minna K. Karjalainen, Savita Karthikeyan, Clare Oliver‐Williams, Eeva Sliz, Elias Allara, Praveen Surendran, +80 more
3citations -
Trans-ancestry genome-wide association study identifies novel genetic mechanisms in rheumatoid arthritis2021 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi C. Terao, Yang Luo, Kyuto Sonehara, Kensuke Yamaguchi, +82 more
14citations -
OmniPath: integrated knowledgebase for multi-omics analysis2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Dénes Türei, Jonathan Schaul, Nicolàs Palacio‐Escat, Balázs Bohár, Yunfan Bai, Francesco Ceccarelli, +25 more
0citations -
Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation2020 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Anubha Mahajan, Cassandra Nichole Spracklen, Weihua Zhang, Maggie C. Y. Ng, Lauren E. Petty, Hidetoshi Kitajima, +92 more
27citations -
Stroke genetics informs drug discovery and risk prediction across ancestries2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Stéphanie Debette, Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, +94 more
9citations -
Mapping the aetiological foundations of the heart failure spectrum using human genetics2023 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Albert Carl Henry, Xiaodong Mo, Chris Finan, Mark D. Chaffin, Doug Speed, Hanane G. Issa, +91 more
6citations -
The genetic diversity of the soybean rust pathogen Phakopsora pachyrhizi has been driven by two major evolutionary lineages2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Yeasts and Rust Fungi Studies Open access
Vinícius Delgado da Rocha, Everton Geraldo Capote Ferreira, Fernanda Machado Castanho, Marcia Kamogae Kuwahara, Claudia Vieira Godoy, M. C. Meyer, +10 more
2citations -
Trio-based whole exome sequencing in patients with suspected sporadic inborn errors of immunity: a retrospective cohort study2022 medRxiv preprint Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Anne Hebert, Annet Simons, Janneke H. M. Schuurs-Hoeijmakers, Hans J. P. M. Koenen, Evelien Zonneveld‐Huijssoon, Stefanie Henriet, +14 more
2citations -
Genomic and phenomic insights from an atlas of genetic effects on DNA methylation2020 medRxiv preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Josine L. Min, Gibran Hemani, Eilis J. Hannon, Koen F. Dekkers, Juan Castillo Fernandez, René Luijk, +92 more
36citations -
Functional diversity of soil microbial communities increases with ecosystem development2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Soil Carbon and Nitrogen Dynamics Open access
Tord Ranheim Sveen, Maria Viketoft, Jan Bengtsson, Justine D.M. Lejoly, Franz Buegger, Karin Pritsch, +6 more
1citations -
Wheat mlo Mutants Show Allele-Specific Levels of Enhanced Susceptibility to the Hemibiotrophic Fungal Pathogen Magnaporthe oryzae pv. Triticum2020 Preprints.org preprint Agricultural and Biological Sciences Wheat and Barley Genetics and Pathology Open access
Katrin Grüner, Tobias Esser, Johanna Acevedo‐Garcia, Matthias Freh, Michael Habig, Roxana Strugala, +3 more
1citations