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Immunohistochemical Evaluation of Cathepsin B, L, and S Expression in Breast Cancer Patients2024 Molecular Imaging and Biology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Daan G. J. Linders, Okker D. Bijlstra, Laura C. Fallert, N. Geeske Dekker-Ensink, Taryn L. March, Martin Pool, +9 more
10citations -
Application of a Highly Selective Cathepsin S Two-step Activity-Based Probe in Multicolor Bio-Orthogonal Correlative Light-Electron Microscopy2021 Frontiers in Chemistry article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Floris J. van Dalen, Thomas Bakkum, Tyrza van Leeuwen, Mirjam G. J. Groenewold, Edgar Deu, Abraham J. Koster, +2 more
13citations -
Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Tom J. Harryvan, Marten Visser, Linda de Bruin, Leonie G Plug, Lisa Griffioen, Arend Mulder, +12 more
42citations -
Formaldehyde treatment of proteins enhances proteolytic degradation by the endo-lysosomal protease cathepsin S2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access cited by 1 patent
Thomas J. M. Michiels, Hugo D. Meiring, Wim Jiskoot, Gideon F. A. Kersten, Bernard Metz
15citations -
Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors2020 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms cited by 10 patents
Markus Schade, Beatrix Merla, Bernhard Lesch, Markus Wagener, Simone Timmermanns, Katrien Pletinckx, +1 more
15citations -
Extracellular Cathepsin B Is a Potential Therapeutic Target in Hepatocellular Carcinoma2025 Liver international communications. article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Hester van Mourik, Annemarie J. F. Westheim, Carolin Victoria Schneider, Lara M. Stoffels, Ewa Wieczerzak, Jorn P.J.M. Steeghs, +6 more
0citations -
Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L2021 International Journal of Molecular Sciences article Medicine SARS-CoV-2 and COVID-19 Research Open access
Elisa Costanzi, Maria Kuzikov, Francesca Esposito, Simone Albani, Nicola Demitri, Barbara Giabbai, +5 more
91citations -
Plasma Cathepsin D Activity Rather Than Levels Correlates With Metabolic Parameters of Type 2 Diabetes in Male Individuals2020 Frontiers in Endocrinology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access cited by 1 patent
Lingling Ding, Tom Houben, Yvonne Oligschlaeger, Albert V. Bitorina, Bart J. Verwer, Maarten E. Tushuizen, +1 more
29citations -
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection2020 Nature Microbiology article Biochemistry, Genetics and Molecular Biology Inflammasome and immune disorders Open access
Joel Selkrig, Nan Li, Annika Hausmann, Matthew Mangan, Matylda Zietek, André Mateus, +15 more
48citations -
Proteome and Secretome Profiling of the Melanoma-Induced Transition Toward Immune Incompetent Dendritic Cells Reveals Enhanced IDO1, Cathepsin, and Legumain Activity2025 Molecular & Cellular Proteomics article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Anouk M. D. Becker, Bob J. Ignacio, Jelmer J. Dijkstra, Iván Ramos‐Tomillero, Floris J. van Dalen, Laura E. Edgington‐Mitchell, +4 more
2citations -
Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 82025 ChemistryEurope article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, FERRY A. OSSENDORP, +1 more
0citations -
SPRAYDYE: a phase I/II randomised pilot study to assess the safety and feasibility of topically applied AKRO-6qcICG, a cathepsin-activatable fluorescent imaging agent, for real-time intraoperative resection margin assessment in breast-conserving surgery
Cedric M. W. Pesch, Daan G. J. Linders, Taryn L. March, Martin Pool, A. Rob P.M. Valentijn, Denise E. Hilling, +11 more
0citations -
Ex vivo fluorescence-guided resection margin assessment in breast cancer surgery using a topically applied, cathepsin-activatable imaging agent2024 Pharmacological Research article Medicine Optical Imaging and Spectroscopy Techniques Open access
Daan G. J. Linders, Okker D. Bijlstra, Ethan Walker, Taryn L. March, Martin Pool, A. Rob P.M. Valentijn, +17 more
5citations -
Increased Bone Resorption during Lactation in Pycnodysostosis2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases Open access
Ineke D.C. Jansen, Socrates E. Papapoulos, Nathalie Bravenboer, Teun J. de Vries, Natasha M. Appelman‐Dijkstra
7citations -
Prior Venous Thromboembolism Defines Distinct Genetic and Molecular Phenotypes in Chronic Thromboembolic Pulmonary Hypertension2026 Arteriosclerosis Thrombosis and Vascular Biology article Medicine Pulmonary Hypertension Research and Treatments
Zhu Zhang, mengjie Duo, Xiaofan Ji, Bingzhang Zou, Haobo Li, Kuangxun Li, +22 more
0citations -
Degradomics-Based Analysis of Tetanus Toxoids as a Quality Control Assay2020 Vaccines article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Thomas J. M. Michiels, Wichard Tilstra, Martin Hamzink, Justin W. de Ridder, Maarten Danial, Hugo D. Meiring, +3 more
8citations -
Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Sonnal Lohia, Agnieszka Latosińska, Jérôme Zoidakis, Manousos Makridakis, Harald Mischak, Griet Glorieux, +2 more
4citations