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Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains2023 Nature Communications article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Leoni Abendstein, Douwe J. Dijkstra, Rayman T.N. Tjokrodirijo, Peter A. van Veelen, Leendert Adrianus Trouw, Paul J. Hensbergen, +1 more
50citations -
Oxidation and Deamidation of Monoclonal Antibody Products: Potential Impact on Stability, Biological Activity, and Efficacy2021 Journal of Pharmaceutical Sciences article Biochemistry, Genetics and Molecular Biology Protein purification and stability cited by 3 patents
Surbhi Gupta, Wim Jiskoot, Christian Schöneich, Anurag Singh Rathore
155citations -
Antibody-dependent cellular cytotoxicity-inducing antibodies enhance the natural killer cell anti-cancer response against patient-derived pancreatic cancer organoids2023 Frontiers in Immunology article Immunology and Microbiology Immune Cell Function and Interaction Open access
Nicky A. Beelen, Merel R. Aberle, Virginia Bruno, Steven W.M. Olde Damink, Gerard M.J. Bos, Sander S. Rensen, +1 more
23citations -
Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex2022 Journal of Innate Immunity article Immunology and Microbiology Complement system in diseases Open access
Heidi Gytz Olesen, Iliana Michailidou, Wioleta Milena Zelek, Jeroen P. Vreijling, Patrick Ruizendaal, Ferry de Klein, +11 more
14citations -
The influenza hemagglutinin stem antibody CR9114: Evidence for a narrow evolutionary path towards universal protection2022 Frontiers in Virology article Medicine Influenza Virus Research Studies Open access cited by 1 patent
Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela M. Phillips, Michael M. Desai, +5 more
18citations -
DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation2024 Journal of the American Chemical Society article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Leoni Abendstein, Willem E. M. Noteborn, Luc S. Veenman, Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leendert Adrianus Trouw, +1 more
16citations -
Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration2022 Frontiers in Pharmacology article Neuroscience Barrier Structure and Function Studies Open access
Arthur J. Van De Vyver, Antje‐Christine Walz, Mariette Heins, Afsaneh Abdolzade‐Bavil, Thomas E. Kraft, Inja Waldhauer, +1 more
19citations -
Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers2020 Cell Reports article Medicine Viral Infections and Outbreaks Research Open access cited by 15 patents
Lucy Rutten, Morgan S. A. Gilman, Sven Blokland, Jarek Juraszek, Jason S. McLellan, Johannes P. M. Langedijk
80citations -
Carbon Source-Dependent Changes of the Structure of Streptococcus pneumoniae Capsular Polysaccharide with Serotype 6F2021 International Journal of Molecular Sciences article Medicine Pneumonia and Respiratory Infections Open access
Joel P. Werren, Lukas J. Troxler, Oluwaseun Rume-Abiola Oyewole, Alban Ramette, Silvio D. Brugger, Rémy Bruggmann, +6 more
14citations -
Targeting Cyclophilin A in the Cardiac Microenvironment Preserves Heart Function and Structure in Failing Hearts2024 Circulation Research article Biochemistry, Genetics and Molecular Biology Signaling Pathways in Disease
Manuel Sigle, Anne‐Katrin Rohlfing, Melanie Cruz Santos, Timo Kopp, Konstantin Krutzke, Vincent Gidlund, +17 more
14citations -
Site-specific profiling of structure and function of Igµ B cell receptor glycans2026 Nature Communications article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Miles D. Holborough-Kerkvliet, Lise Hafkenscheid, Sanne Kroos, Roxane Biersteker, Ojas Singh, Elisa Fadda, +5 more
1citations -
Comprehensive Multidimensional Liquid Chromatography–Mass Spectrometry for the Characterization of Charge Variants of a Bispecific Antibody2022 Journal of the American Society for Mass Spectrometry article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Ingrid Grunert, Katrin Heinrich, Michael Hingar, Juliane Ernst, Katrin Bomans, Arnaud Fevre, +3 more
18citations -
SARS-CoV-2 Antibody Prevalence Across Unvaccinated Health Care Workers During the COVID-19 Pandemic in Yemen: Cross-Sectional Study2025 JMIR Public Health and Surveillance article Medicine SARS-CoV-2 and COVID-19 Research Open access
Eihab Al‐Herwi, Maryam Baras, Khadega Alhetar, Mohammed Farhan, R.A. Saleh, Amani As-suhbani, +8 more
0citations -
Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility–Mass Spectrometry2023 Analytical Chemistry article Chemistry Mass Spectrometry Techniques and Applications Open access
Guusje van Schaick, Elena Domínguez‐Vega, J.-G. Castel, Manfred Wuhrer, Oscar Hernandez‐Alba, Sarah Cianférani
17citations