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Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phase I, open-label, single-arm, dose-escalation study (REACtiVe-2 trial)
Sai Ping Lau, Freek R. van ‘t Land, Sjoerd H. van der Burg, Marjolein Y.V. Homs, Martijn P. Lolkema, Joachim G.J.V. Aerts, +1 more
9citations -
Multiscale imaging of therapeutic anti-PD-L1 antibody localization using molecularly defined imaging agents2022 Journal of Nanobiotechnology article Medicine Radiopharmaceutical Chemistry and Applications Open access
Iris M. Hagemans, Peter J. Wierstra, Kas Steuten, Janneke D.M. Molkenboer‐Kuenen, Duco van Dalen, Martin ter Beest, +7 more
10citations -
Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe2024 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Lisa S. den Hollander, Bert L. H. Beerkens, Sebastian Dekkers, Jacobus P. D. van Veldhoven, Natalia V. Ortiz Zacarı́as, Cas van der Horst, +6 more
2citations -
Endopeptidase Cleavage of Anti-Glomerular Basement Membrane Antibodies in vivo in Severe Kidney Disease: An Open-Label Phase 2a Study2022 Journal of the American Society of Nephrology article Medicine Vasculitis and related conditions Open access cited by 2 patents
Fredrik Uhlin, Wladimir M. Szpirt, Andreas Kronbichler, Annette N. Bruchfeld, Inga Soveri, Lionel P. E. Rostaing, +14 more
70citations -
Replication, safety and immunogenicity of the vectored Ebola vaccine rVSV-ΔG-ZEBOV-GP in a sub-Saharan African paediatric population: A randomised controlled, open-label trial in children aged 1-12 years living in Lambaréné, Gabon
Ayodele Kamal ALABI, Kossiwa Kokou, Saïdou Mahmoudou, Ranmali Kavishna, Sravya Sowdamini Nakka, Sylvia Rothenberger, +12 more
8citations -
Oral Monotherapy with Iptacopan, a Proximal Complement Inhibitor of Factor B, Has Superior Efficacy to Intravenous Terminal Complement Inhibition with Standard of Care Eculizumab or Ravulizumab and Favorable Safety in Patients with Paroxysmal Nocturnal Hemoglobinuria and Residual Anemia: Results from the Randomized, Active-Comparator-Controlled, Open-Label, Multicenter, Phase III Apply-PNH Study
Régis Peffault de Latour, Alexander Roeth, Austin Gladston Kulasekararaj, Phillip Scheinberg, Yasutaka Ueda, Carlos M. de Castro, +15 more
23citations -
Dual Site-Specific Chemoenzymatic Antibody Fragment Conjugation Using CRISPR-Based Hybridoma Engineering2021 Bioconjugate Chemistry article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 2 patents
Camille M. Le Gall, Johan M. S. van der Schoot, Iván Ramos‐Tomillero, Melek Parlak Khalily, Floris J. van Dalen, Zacharias Wijfjes, +7 more
26citations -
Radiolabeled Monoclonal Antibody Against Colony-Stimulating Factor 1 Receptor Specifically Distributes to the Spleen and Liver in Immunocompetent Mice2021 Frontiers in Oncology article Medicine Radiopharmaceutical Chemistry and Applications Open access
Stijn J.H. Waaijer, Frans V. Suurs, Cheei‐Sing Hau, Kim Vrijland, Karin E. de Visser, Derk Jan A. de Groot, +3 more
9citations -
A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners2023 Glycobiology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Miles D. Holborough-Kerkvliet, Greta Mucignato, Sam J. Moons, Venetia Psomiadou, Rohit Sai Reddy Konada, Nichole J. Pedowitz, +11 more
5citations -
Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors2021 Molecular Imaging and Biology article Medicine Optical Imaging and Spectroscopy Techniques Open access cited by 3 patents
Victor M. Baart, Labrinus van Manen, Shadhvi S. Bhairosingh, Floris A. Vuijk, Luisa Iamele, Hugo de Jonge, +8 more
17citations -
Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures2021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Nuclear Structure and Function Open access
Merel Stiekema, Frans C. S. Ramaekers, Dimitrios Kapsokalyvas, Marc A. M. J. van Zandvoort, Rogier J. A. Veltrop, Jos L. V. Broers
21citations -
Long-term safety, tolerability, and efficacy of subcutaneous efgartigimod PH20 in generalized myasthenia gravis: final results from a phase 3 open-label extension study (ADAPT-SC+)
Andreas Meisel, Carlo Giuseppe Antozzi, Ratna Bhavaraju-Sanka, Jan De Bleecker, Wan-Yi Huang, Rosa H. Jimenez, +10 more
0citations -
99mTc‑labeled single-domain antibody for SPECT/CT assessment of HER2 expression in diverse cancer types2022 European Journal of Nuclear Medicine and Molecular Imaging article Medicine Radiopharmaceutical Chemistry and Applications Open access
Betül Altunay, Andreas Goedicke, Oliver Winz, Fabian Hertel, Dirk von Mallek, Levente K. Meszaros, +5 more
25citations -
[11C]Carboxylated Tetrazines for Facile Labeling of Trans‐Cyclooctene‐Functionalized PeptoBrushes2021 Macromolecular Rapid Communications article Medicine Radiopharmaceutical Chemistry and Applications Open access
Rocío García Vázquez, Umberto Maria Battisti, Vladimir Shalgunov, Gabriela Giannina Schäfer, Matthias Barz, Matthias M. Herth
14citations -
Tc-99m-labeled single domain antibody for non-invasive determination of the HER2 expression2022 Nuklearmedizin - NuclearMedicine article Medicine Radiopharmaceutical Chemistry and Applications
Betül Altunay, Agnieszka Morgenroth, Alexandru Florea, Levente K. Meszaros, Felix Manuel Mottaghy
0citations -
Longitudinal evaluation of the biodistribution and cellular internalization of the bispecific CD3xTRP1 antibody in syngeneic mouse tumor models2023 Journal for ImmunoTherapy of Cancer article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Gerwin W. Sandker, Jim Middelburg, Evienne Wilbrink, Janneke D.M. Molkenboer‐Kuenen, Erik H.J.G. Aarntzen, Thorbald van Hall, +1 more
8citations -
A label-free electrochemical aptasensor enables ultrasensitive and specific detection of neurofilament light2026 Biosensors and Bioelectronics article Biochemistry, Genetics and Molecular Biology Advanced biosensing and bioanalysis techniques Open access
Hangyu Li, Qinyu Hu, Krisztina Percze, Mateo Alejandro Martínez-Roque, Shengkai Sun, Francesca Santoro, +2 more
3citations -
Safety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial
Etienne Karita, Julien M. Nyombayire, Rosine Ingabire, Amelia Mazzei, Tyronza Sharkey, Jeannine Mukamuyango, +12 more
19citations