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Autoreactive B cells in rheumatoid arthritis consist of activated CXCR3+ memory B cells and plasmablasts2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Sanne Reijm, Joanneke C. Kwekkeboom, Nienke J. Blomberg, Jolien Suurmond, Diane van der Woude, René E. M. Toes, +1 more
1citations -
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL2024 The Journal of Experimental Medicine article Medicine Lymphoma Diagnosis and Treatment Open access
Janneke A. Eken, Marvyn T. Koning, Kristýna Kupcová, Julieta Sepúlveda-Yáñez, Ruben A. L. de Groen, Edwin Quinten, +10 more
19citations -
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis2020 Science Translational Medicine article Medicine Rheumatoid Arthritis Research and Therapies Open access
Hendy Kristyanto, Nienke J. Blomberg, Linda M. Slot, Ellen I. H. van der Voort, Priscilla F. Kerkman, Aleida M. Bakker, +8 more
117citations -
OP0017 ACTIVE LUPUS NEPHRITIS PATIENTS DISPLAY AN INCREASED PROPORTION OF RECENTLY ACTIVATED NAÏVE DNA-REACTIVE B CELLS2023 Annals of the Rheumatic Diseases conference-abstract Medicine Systemic Lupus Erythematosus Research Open access
Kittikorn Wangriatisak, Francesca Faustini, Charlotte de Vries, Prapaporn Pisitkun, Patchanee Chootong, Vivianne Malmström, +1 more
0citations -
AB0022 AUTOREACTIVE B CELLS IN RHEUMATOID ARTHRITIS DISPLAY AN ACTIVATED PHENOTYPE OF RECENT ANTIGEN EXPOSURE2021 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies
Nienke J. Blomberg, Hendy Kristyanto, Tom W. J. Huizinga, René E. M. Toes, Hans Ulrich Scherer
0citations -
EOMES and IL-10 regulate anti-tumor activity of PD-1 + CD4 + T-cells in B-cell Non-Hodgkin lymphoma2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +10 more
4citations -
Restoration of T and B Cell Differentiation after RAG1 Gene Transfer in Human RAG1 Defective Hematopoietic Stem Cells2024 Biomedicines article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Nataël Sorel, Francisco Díaz-Pascual, Boris Bessot, Hanem Sadek, Chloé Mollet, Myriam Chouteau, +12 more
5citations -
DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing2020 EBioMedicine article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 59 patents
Patrick J. Engelberts, Ida H. Hiemstra, Bart de Jong, Danita H. Schuurhuis, Joyce I. Meesters, Irati Beltrán Hernández, +10 more
181citations -
Distinct morphological features of malignant cells in large B-cell lymphoma identified by soft-segmentation in imaging-based spatial proteomics2025 Blood conference-abstract Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Troy Noordenbos, Marieke E. Ijsselsteijn, Noel de Miranda, Joost S.P. Vermaat, Mohammad Shahrokh Esfahani
0citations -
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia2022 Science Translational Medicine article Medicine CAR-T cell therapy research Open access cited by 2 patents
Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Annie Etuk, +52 more
204citations -
Rationale for and Design of Papilio-1: A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Feasibility, Safety, and Efficacy of Point-of-Care-Manufactured Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells (GLPG5301) in Relapsed/Refractory Multiple Myeloma
Niels W.C.J. van de Donk, Sébastien Anguille, Jo Caers, Marte C. Liefaard, Christian J. Jacques, Anna D.D. van Muyden
1citations -
Gut T cell–independent IgA responses to commensal bacteria require engagement of the TACI receptor on B cells2020 Science Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Emilie K. Grasset, Alejo Chorny, Sandra Casas-Recasens, Cindy Gutzeit, Gerold Bongers, Irene Thomsen, +19 more
86citations -
Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet, Anita E. Grootemaat, Kirill Vlaskov, Chaja Feige Jacobs, +10 more
0citations -
Emerging Immune Cell Biomarkers in Primary Membranous Nephropathy: Immune Cell Profiling During Anti-CD20 B Cell-Targeted Therapy2026 International Journal of Molecular Sciences article Medicine Renal Diseases and Glomerulopathies Open access
Christos Georgopoulos, Eleni Stamellou, Αnila Duni, Lefkothea Dova, George Vartholomatos, Ekaterini C. Siomou, +2 more
0citations -
Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis2021 PLoS ONE article Medicine Rheumatoid Arthritis Research and Therapies Open access cited by 1 patent
Linda M. Slot, Rochelle D. Vergroesen, Priscilla F. Kerkman, Ellen Magadalena Staudinger, Sanne Reijm, Hugo J. van Dooren, +4 more
9citations -
Activated CD4+ T Cells and Highly Differentiated Alloreactive CD4+ T Cells Distinguish Operationally Tolerant Liver Transplantation Recipients2021 Liver Transplantation article Immunology and Microbiology T-cell and B-cell Immunology Open access
Aafke A. Duizendstra, Robert Jacobus de Knegt, Shanta Mancham, Mariska Klepper, Dave L. Roelen, Simone H. Brand‐Schaaf, +8 more
12citations