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Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet, Anita E. Grootemaat, Kirill Vlaskov, Chaja Feige Jacobs, +10 more
0citations -
GSTM1 and GSTT1 Double Null Genotypes Determining Cell Fate and Proliferation as Potential Risk Factors of Relapse in Children with Hematological Malignancies after Stem Cell Transplantation.2021 Research Square preprint Biochemistry, Genetics and Molecular Biology Glutathione Transferases and Polymorphisms Open access
Simona Jurković Mlakar, Chakradhara Rao S. Uppugunduri, Tiago Nava, Vid Mlakar, Hadrien G. Golay, Shannon K. D. Robin, +11 more
1citations -
Glutamine and GLS1 are key metabolic checkpoints that Limit T cell Infiltration and Function in HNSCC2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cancer Immunotherapy and Biomarkers Open access
Sonja Decking, Ines Ugele, Katja Dettmer, Gabriel Horkovics-Kovats, Julian Kuenzel, Charlotte L. Zuur, +35 more
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Embryonic nutritional hyperglycemia decreases cell proliferation in the zebrafish retina2022 Research Square preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Ismael Hernández‐Núñez, María Vivero-Lopez, Ana Quelle‐Regaldie, Willem J. DeGrip, Laura E. Sanchez, Ángel Concheiro, +3 more
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Cross-presentation of citrullinated antigens drives cytotoxic CD8 + T cell responses in rheumatoid arthritis2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Rheumatoid Arthritis Research and Therapies Open access
Jae‐Seung Moon, Mengrui Zhang, Laura S. van Dam, Eun Kyung Song, Orr Sharpe, Julie Carman, +6 more
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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte‐Real, Ibrahim Hamad, Mansour Haidar, +14 more
4citations -
A proteomic map of B cell activation and its shaping by mTORC1, MYC and iron2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Olivia James, Linda V. Sinclair, Nadejda Lefter, Andrew J.M. Howden
1citations -
LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Nadia Cobo‐Vuilleumier, Silvia Rodríguez-Fernández, Livia López–Noriega, Petra Isabel Lorenzo, JM Franco, CC Lachaud, +22 more
0citations -
Autocrine inhibition of cell motility can drive epithelial branching morphogenesis in absence of growth2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Mathematics Mathematical Biology Tumor Growth Open access
Elisabeth G. Rens, Mathé T. Zeegers, Iraes Rabbers, András Szabó, Roeland M. H. Merks
0citations -
A FOXO-dependent replication checkpoint restricts proliferation of damaged cells2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Marten Hornsveld, Femke M. Feringa, Lenno Krenning, Jeroen van den Berg, Lydia M.M. Smits, Nguyen BT Nguyen, +4 more
3citations -
Reversing PROTAC-induced ASH2L degradation reactivates proliferation in senescent cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Janina Müller, Mirna Barsoum, Philip Bussmann, Mohamed H. Elsafi Mabrouk, Roksaneh Sayadi-Boroujeni, Anna-Maria Vllaho, +6 more
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Cyclin E/CDK2 deficiency links cell cycle control to intestinal barrier integrity and tight junction regulation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Barrier Structure and Function Studies Open access
Hannes Hatten, Anna M. Verwaayen, Melissa Corcini-Berndt, Emiel P. C. van der Vorst, Daniela Paffen, Yulia Alexandrowna Nevzorova, +3 more
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The biomolecular profiles of extracellular vesicles from odontogenic stem cell lines depict donor-dependent differences and emphasize their therapeutic and regenerative potential2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Yong Xu, Alp Sarisoy, Eva Miriam Buhl, Julian Gonzalez‐Rubio, Anja Lena Thiebes, Sandra Fuest, +3 more
1citations -
KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Lohr, Rossella Pellegrino, Mihael Vucur, Michael T. Singer, Veronika Buettner, +7 more
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Reconstitution of human fetal ovaries reveals niche requirements for primordial germ cell-like cell progression2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm, Albert Blanch-Asensio, Arend W. Overeem, Susana M. Chuva de Sousa Lopes
2citations -
Loss of myeloid cannabinoid CB1 receptor confers atheroprotection by reducing macrophage proliferation and immunometabolic reprogramming2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Yong Wang, Li Guo, Bingni Chen, George Shakir, Mario Volz, Emiel P. C. van der Vorst, +14 more
2citations -
Mapping human natural killer cell development in tonsil2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Ansel P. Nalin, Hiranmayi Ravichandran, André F. Rendeiro, Bethany L. Mundy-Bosse, +9 more
0citations -
Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Hiranmayi Ravichandran, André F. Rendeiro, Aharon G. Freud, Bethany L. Mundy-Bosse, +8 more
5citations -
Fluorescence-activated cell sorting of Escherichia coli L-forms reveals maintained synchronized nucleic acid synthesis dynamics2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bacterial Genetics and Biotechnology Open access
Marjolein E. Crooijmans, Johannes H. DE WINDE, Dennis Claessen
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A soft active matter models explains spiral epithelial cell migration on in-vivo corneas2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cellular Mechanics and Interactions Open access
Kaja Kostanjevec, Rastko Sknepnek, Jon Martin Collinson, Silke Henkes
0citations