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The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling2023 Frontiers in Oncology article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Kathrin Olschok, Bianca Altenburg, Marcelo A. S. Toledo, Angela Maurer, Anne Abels, Fabian Beier, +7 more
15citations -
Guidance on JAK inhibitor treatment for inborn errors of JAK-STAT signaling, 2026: International consensus statement on behalf of the European Society for Immunodeficiencies/European Society for Blood and Marrow Transplantation–Inborn Errors Working Party and ERN-RITA2026 Journal of Allergy and Clinical Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Peter Olbrich, M. Fischer, Àngela Deyà‐Martínez, Concepción Campos-Asensio, Olaf Neth, Jérôme Hadjadj, +41 more
2citations -
Phenotypic variability, not noise, accounts for most of the cell-to-cell heterogeneity in IFN-γ and oncostatin M signaling responses2022 Science Signaling article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Karolina Ewa Zakrzewska, Jarosław Walczak, Karol Nienałtowski, Gerhard Müller‐Newen, Abhyudai Singh, Michał Komorowski
35citations -
Steamed Panax notoginseng Attenuates Anemia in Mice With Blood Deficiency Syndrome via Regulating Hematopoietic Factors and JAK-STAT Pathway2020 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Ginseng Biological Effects and Applications Open access
Zejun Zhang, Yiming Zhang, Min Gao, Xiuming Cui, Yang Yang, Bert van Duijn, +4 more
48citations -
Expression of Interferons Lambda 3 and 4 Induces Identical Response in Human Liver Cell Lines Depending Exclusively on Canonical Signaling2021 International Journal of Molecular Sciences article Immunology and Microbiology interferon and immune responses Open access
Mariia Lunová, Jan Kubovčiak, Barbora Smolková, Mariia Uzhytchak, Kyra Michalova, Alexandr Dejneka, +3 more
8citations -
DOP133 Targeting the JAK-STAT pathway reprograms intestinal fibroblasts and attenuates IBD-associated fibrosis2026 Journal of Crohn s and Colitis conference-abstract Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease
J Su, Bram W. van Os, Sabine de Winter, Erik H.J. Danen, Philip W. Voorneveld, Lukas J.A.C. Hawinkels, +2 more
0citations -
NicheSphere reveals Spp1⁺ macrophages as central hubs coordinating fibrotic remodeling in myeloproliferative neoplasms2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Hélène F.E. Gleitz, Mayra L. Ruiz Tejada Segura, James Shiniti Nagai, Stijn N. R. Fuchs, Gerjanne Vroeg in de Wei, Inge Snoeren, +16 more
1citations -
A multicenter spatial transcriptomics atlas of human tuberculosis and non-tuberculous mycobacterial disease2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Xun Jiang, Leonard Christian, Liang Zhou, Nienke van Unen, Lavinia Neubert, Jan C. Kamp, +13 more
2citations -
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Aurélien J. F. Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Kristina Bennet Emdal, Dorte B. Bekker‐Jensen, +7 more
16citations -
FadA antigen of Fusobacterium nucleatum: implications for ceRNA network in colorectal cancer and adenomatous polyps progression2025 Discover Oncology article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Sama Rezasoltani, Elahe Shams, Moein Piroozkhah, Yaser Aidi, Mehdi Azizmohammad Looha, Parmida Bagheri, +4 more
3citations -
Deciphering the complex clonal heterogeneity of polycythemia vera and the response to interferon alpha2023 Research Square preprint Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Milena Kalmer, Martin Graßhoff, Tiago Maié, Kristina Pannen, Marcelo A. S. Toledo, Margherita Vieri, +13 more
2citations