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Platelet‐Released Growth Factors (PRGFs) Activate NRF2‐ARE and Modulate Inflammatory Response in an NRF2‐Dependent Manner in Primary Human Keratinocytes2025 Journal of Cosmetic Dermatology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Mersedeh Tohidnezhad, Athanassios Fragoulis, Andreas U. Bayer, Hannes Klump, Jens Malte Baron, Thomas Pufe
2citations -
Mining a human transcriptome database for chemical modulators of NRF22020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
John P. Rooney, Brian N. Chorley, Steven W. Hiemstra, Steven Wink, Xuting Wang, Douglas A. Bell, +2 more
54citations -
Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses2022 Toxicology in Vitro article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Bas ter Braak, Janna E. Klip, Steven Wink, Steven W. Hiemstra, Sarah Lucy Cooper, A. Middleton, +2 more
8citations -
Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis2022 BMC Musculoskeletal Disorders article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases Open access
Yusuke Kubo, Jesus Abraham Herrera Gonzalez, Rainer Beckmann, Marek Weiler, H. Pahlavani, Mauricio Cruz Saldívar, +12 more
9citations -
Chronic Nrf2 deficiency affects age- and gender- dependent bone and cartilage acquisition in murine femur2021 Osteologie/Osteology conference-paper Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases
A. Dávalos Herrera, Mersedeh Tohidnezhad, Athanassios Fragoulis, CJ Wruck, Stefanie Rosenhain, Holger Jahr, +3 more
0citations -
Deciphering the quantitative relationship between NRF2 and SRXN1 through semi-mechanistic computational modeling2025 Toxicology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Raju Prasad Sharma, Liesanne Wolters, Bas ter Braak, Marije Niemeijer, Andrew White, Bob van de Water, +2 more
1citations -
Imaging-based temporal dynamics of electrophile-induced NRF2 signaling in liver cells identifies adaptive versus adverse repeated exposure conditions2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress
Marije Niemeijer, Liesanne Wolters, Bas ter Braak, Hiral Patel, Raju Sharma, Beate Nicol, +5 more
1citations -
Luteolin Induces Nrf2 Activity in C2C12 Cells: Implications for Muscle Health2025 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Frank Suhr, Thomas Pufe, Christoph Jan Wruck, Athanassios Fragoulis
9citations -
Sulforaphane Exerts Beneficial Immunomodulatory Effects on Liver Tissue via a Nrf2 Pathway-Related Mechanism in a Murine Model of Hemorrhagic Shock and Resuscitation2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Weiqiang Liang, Johannes Greven, Kang Qin, Athanassios Fragoulis, Klemens Horst, Felix Bläsius, +5 more
19citations -
Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression2022 Redox Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Athanassios Fragoulis, Julia Schenkel, Nicole Schröder, Elisa Fabiana Brandt, Mathias Weiand, Tabita Neu, +9 more
11citations -
Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure2022 Scientific Reports article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Steven W. Hiemstra, Mirjam Fehling-Kaschek, Isoude A. Kuijper, Luc J. M. Bischoff, Lukas S. Wijaya, Marcus Rosenblatt, +7 more
31citations