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Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C2025 eLife preprint Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Cilia R. Pothast, Ian Derksen, Anneloes van der Plas - van Duijn, Angela el Hebieshy, Wesley Huisman, Kees L. M. C. Franken, +7 more
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Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C2026 eLife preprint Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Cilia R. Pothast, Ian Derksen, Anneloes van der Plas - van Duijn, Angela el Hebieshy, Wesley Huisman, Kees L. M. C. Franken, +9 more
0citations -
Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C2025 eLife preprint Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Cilia R. Pothast, Ian Derksen, Anneloes van der Plas - van Duijn, Angela el Hebieshy, Wesley Huisman, Kees L. M. C. Franken, +9 more
0citations -
Temperature-based MHC class-I multimer peptide exchange for human HLA-A, B and C.2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Cilia R. Pothast, Ian Derksen, Anneloes van der Plas - van Duijn, Angela el Hebieshy, Wesley Huisman, Kees L. M. C. Franken, +7 more
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Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope2022 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G.D. Kester, Dennis F.G. Remst, Dirk M. van der Steen, +6 more
3citations -
Response: Commentary: An In Silico–In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients2021 Frontiers in Immunology editorial Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access cited by 2 patents
Michele Mishto, Guillermo Rodriguez-Hernandez, Jacques Neefjes, Henning Urlaub, Juliane Liepe
10citations -
370 Identification and validation of a T cell receptor recognizing shared HLA-A02:01 presented epitope from TP53 frameshift2024 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immunotherapy and Immune Responses Open access
Michael V. Martin, Saskia J A M Santegoets, Jamie van Langelaar, Wim van Esch, Hugo Olsman, Finn Edwards, +4 more
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A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity2020 Blood article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 4 patents
Marthe C.J. Roex, Lois Hageman, Sabrina A.J. Veld, Esther van Egmond, Conny Hoogstraten, Christian Stemberger, +4 more
16citations -
Selection of a Single Domain Antibody, Specific for an HLA-Bound Epitope of the Mycobacterial Ag85B Antigen2020 Frontiers in Immunology article Medicine Monoclonal and Polyclonal Antibodies Research Open access cited by 2 patents
Paola Andrea Ortega-Portilla, Mayra Silva‐Miranda, Alfredo Torres‐Larios, Eduardo Campos-Chávez, Kees L. M. C. Franken, Tom H. M. Ottenhoff, +2 more
8citations -
Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations -
Intradermal Naked DNA Vaccination by DNA Tattooing for Mounting Tumor-Specific Immunity in Stage IV Melanoma Patients: A Phase I Clinical Trial2024 Oncology Research and Treatment article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Marnix H. Geukes Foppen, Maartje W. Rohaan, Jessica S.W. Borgers, Daisy Philips, Florry A. Vyth‐Dreese, Jos H. Beijnen, +3 more
6citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
17citations -
HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical Study
Peter van Balen, Inge Jedema, Marleen M. van Loenen, Renate de Boer, H.M. van Egmond, Renate S. Hagedoorn, +9 more
42citations -
Amino acids at position 5 in the peptide/MHC binding region of a public virus‐specific TCR are completely inter‐changeable without loss of function2022 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Wesley Huisman, Melanie de Gier, Lois Hageman, Alina S. Shomuradova, Didier A.T. Leboux, Derk Amsen, +2 more
3citations -
A hot trick for efficient peptide exchange on MHC class I multimers for large-scale detection of antigen-specific T cells2022 Molecular Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches
Jolien J. Luimstra, Malgorzata Anna Garstka, Jacques Neefjes, Huib Ovaa
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21P: Primary analysis of safety, efficacy and immunogenicity of the therapeutic cancer vaccine PDC*lung01 with or without pembrolizumab in NSCLC: A multicenter phase I/II study2025 Journal of Thoracic Oncology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
J.F. Vansteenkiste, I. Demedts, K. Cuppens, Elvire Pons Tostivint, E. Wauters, Frank Johannes Borm, +13 more
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T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia_flow_cytometry_data_32026 Zenodo (CERN European Organization for Nuclear Research) dataset Medicine CAR-T cell therapy research Open access
Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more
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T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia_flow_cytometry_data_32026 Zenodo (CERN European Organization for Nuclear Research) dataset Medicine CAR-T cell therapy research Open access
Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more
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T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia_flow_cytometry_data_12026 Zenodo (CERN European Organization for Nuclear Research) dataset Medicine CAR-T cell therapy research Open access
Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more
0citations -
T-cell receptors targeting distinct FLT3-D835Y neoantigens display differential reactivity toward acute myeloid leukemia_flow_cytometry_data_12026 Zenodo (CERN European Organization for Nuclear Research) dataset Medicine CAR-T cell therapy research Open access
Nadine Struckman, M. Willy Honders, Georgia Koutsoumpli, Rob C. M. de Jong, Dyantha I. van der Lee, Michel G.D. Kester, +11 more
0citations -
1181 Therapeutic vaccines consisting of cancer germline antigen-based synthetic long peptides are immunogenic in human hepatocellular carcinoma patients2022 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immunotherapy and Immune Responses Open access
Yannick Sebastiaan Rakké, Marij Schoenmaekers-Welters, Lisanne Noordam, Sanne Boekestijn, Luc Magré, Robbie J. Luijten, +12 more
0citations