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Helicase-deficient TFIIH causes severe disease features via persistent DNA excision without damage removal2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
David Häckes, Arjan F. Theil, Geun Hoe Kim, Y. J. Kim, Paula J. van der Meer, Céline Van Wassenhove, +9 more
0citations -
Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent
Juliette A. Kamp, Bennie B. L. G. Lemmens, Ron J Romeijn, S. C. Changoer, Robin van Schendel, Marcel Tijsterman
35citations -
Hierarchical mechanisms control the clearance of DNA lesion–stalled RNA polymerase II2026 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Paula J. van der Meer, George Yakoub, Kotaro Tsukada, Yuka Nakazawa, Tomoo Ogi, Martijn S. Luijsterburg
8citations -
Division of labor within polymerase theta in repair of CRISPR-induced DNA breaks in Arabidopsis thaliana2025 PNAS Nexus article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lycka Kamoen, Dieuwertje A. de Bruin, Lejon E. M. Kralemann, Mandy M D A Wildhagen, Robin van Schendel, Paul J. J. Hooykaas, +2 more
2citations -
Chl1 helicase controls replication fork progression by regulating dNTP pools2022 Life Science Alliance article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Amandine Batté, Sophie C. van der Horst, Mireille Tittel-Elmer, Su Ming Sun, Sushma Sharma, Jolanda S. van Leeuwen, +2 more
2citations -
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks2020 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, +7 more
55citations -
FAN1-mediated translesion synthesis and POLQ/HELQ-mediated end joining generate interstrand crosslink-induced mutations2025 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Jip Verschuren, Robin van Schendel, Ivo van Bostelen, Alexander E. E. Verkennis, Puck Knipscheer, Marcel Tijsterman
2citations -
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability2024 PLoS Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Aurora Yáñez‐Vilches, Antonia María Romero, Marta Barrientos‐Moreno, Esther Cruz, Román González‐Prieto, Sushma Sharma, +2 more
3citations -
FANCJ and RTEL1 facilitate pre-replication complex disassembly following replisome collision2026 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
George Cameron, Simran Negi, Koichi Sato, Sevim Yardimci, Çağla Kaya, Cameron McClymont, +4 more
0citations -
Physical interactions between MCM and Rad51 facilitate replication fork lesion bypass and ssDNA gap filling by non-recombinogenic functions2021 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Maria Jose Cabello-Lobato, Cristina González‐Garrido, María I. Cano-Linares, Ronald P.C. Wong, Aurora Yáñez‐Vilches, Macarena Morillo‐Huesca, +5 more
23citations -
TONSL suppresses polymerase theta-dependent tandem duplications through chromatin-guided repair2026 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Robin van Schendel, Ron J Romeijn, Lejon E. M. Kralemann, Paul J. J. Hooykaas, Marcel Tijsterman
0citations -
FAN1-mediated translesion synthesis and POLQ/HELQ-mediated end joining generate interstrand crosslink-induced mutations2024 Research Square preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Marcel Tijsterman, Jip Verschuren, Robin van Schendel, Ivo van Bostelen, Puck Knipscheer
0citations -
Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC2025 Breast Cancer Research article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Nasi Liu, Jurjun J S van der Velde, Sherien Ramdjielal, Esmee Koedoot, Nila K. van Overbeek, Daisy Batenburg, +3 more
5citations -
Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition2026 American Journal of Medical Genetics Part A article Medicine Genetic factors in colorectal cancer Open access
Noah C. Helderman, Carli M.J. Tops, Jelmer Legebeke, Marcos Díaz‐Gay, Diantha Terlouw, Lisa E.E.L.O. Lashley, +9 more
0citations -
SMARCAD1 Regulates R-Loops at Active Replication Forks Linked to Cancer Mutation Hotspots2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Sidrit Uruci, Nicole M. Hoitsma, María Eugenia Soler-Oliva, Aleix Bayona‐Feliú, Vincent Gaggioli, Maria Luisa García-Rubio, +9 more
3citations
25 results