Papers matching “DNA double-strand breaks” 61
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Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks2022 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent
Bert van de Kooij, Alex Kruswick, Haico van Attikum, Michael B. Yaffe
69citations -
Competition between homologous chromosomal DNA and exogenous donor DNA to repair CRISPR/Cas9-induced double-strand breaks in Aspergillus niger2024 Fungal Biology and Biotechnology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Selina Forrer, Mark Arentshorst, Prajeesh Kooloth-Valappil, Jaap Visser, Arthur F. J. Ram
0citations -
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks2020 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, +7 more
55citations -
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks2024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Bert van de Kooij, Fenna J. van der Wal, Magdalena B. Rother, Wouter W. Wiegant, Pau Creixell, Merula Stout, +6 more
29citations -
ZMYM2 restricts 53BP1 at DNA double-strand breaks to favor BRCA1 loading and homologous recombination2022 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Seong-Ok Lee, Hsin‐Ru Chan, Martijn S. Luijsterburg, Justin W. C. Leung, Kyle M. Miller
39citations -
Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent
Juliette A. Kamp, Bennie B. L. G. Lemmens, Ron J Romeijn, S. C. Changoer, Robin van Schendel, Marcel Tijsterman
35citations -
Poly(ADP-ribosyl)ation temporally confines SUMO-dependent ataxin-3 recruitment to control DNA double-strand break repair2021 Journal of Cell Science article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Annika Pfeiffer, Laura K. Herzog, Martijn S. Luijsterburg, Rashmi G. Shah, Magdalena B. Rother, Henriette Stoy, +4 more
10citations -
Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair2024 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Marieke R. Wensveen, Aditya A. Dixit, Robin van Schendel, Apfrida Kendek, Jan-Paul Lambooij, Marcel Tijsterman, +2 more
6citations -
PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks2020 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Ignacio Alonso‐de Vega, Maria Cristina Paz‐Cabrera, Magdalena B. Rother, Wouter W. Wiegant, Cintia Checa-Rodríguez, Juan Ramon Hernandez-Fernaud, +4 more
35citations -
Small tandem DNA duplications result from CST-guided Pol α-primase action at DNA break termini2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Marcel Tijsterman
38citations -
Genetic dissection of mutagenic repair and T-DNA capture at CRISPR-induced DNA breaks in Arabidopsis thaliana2024 PNAS Nexus article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lycka Kamoen, Lejon E. M. Kralemann, Robin van Schendel, Niels van Tol, Paul J. J. Hooykaas, Sylvia de Pater, +1 more
12citations -
Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways2023 Cell Reports article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 5 patents
Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Sven van der Vlies, Juliette A. Kamp, +5 more
75citations -
EXO1 protects BRCA1-deficient cells against toxic DNA lesions2024 Molecular Cell article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 2 patents
Bert van de Kooij, Anne Schreuder, Raphael Pavani, Veronica Garzero, Sidrit Uruci, Tiemen J. Wendel, +13 more
44citations -
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin2020 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Cancer therapeutics and mechanisms Open access cited by 4 patents
Xiaohang Qiao, Sabina Y. van der Zanden, Dennis P. A. Wander, Daniel Borràs, Ji‐Ying Song, Xiaoyang Li, +21 more
177citations -
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations2024 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Ivan Kuzmin, Marilin Moor, Núria Muñoz-Subirana, +7 more
18citations -
Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining2021 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Jenny Kaur Singh, Rebecca Smith, Magdalena B. Rother, Anton J.L. de Groot, Wouter W. Wiegant, Kees Vreeken, +9 more
50citations -
ERCC1mutations impede DNA damage repair and cause liver and kidney dysfunction in patients2020 The Journal of Experimental Medicine article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Katja Apelt, Susan M. White, Hyun Suk Kim, Jung-Eun Yeo, Annelotte P. Wondergem, Martin A. Rooimans, +13 more
36citations -
MUSICiAn: genome-wide identification of genes involved in DNA repair via control-free mutational spectra analysis2026 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Colm Seale, Marco Barazas, Robin van Schendel, Marcel Tijsterman, Joana P. Gonçalves
3citations -
Evaluation of Proton-Induced DNA Damage in 3D-Engineered Glioblastoma Microenvironments2022 ACS Applied Materials & Interfaces article Medicine Radiation Therapy and Dosimetry Open access cited by 3 patents
Qais Akolawala, Marta Rovituso, Henri H. Versteeg, Araci M. R. Rondon, Angelo Accardo
38citations