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Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug–Drug Interaction Studies2023 Drug Metabolism and Disposition article Biochemistry, Genetics and Molecular Biology Fibroblast Growth Factor Research
Mario Mezler, Devorah C. Goldman, Matthew Hoffmann, Aki T. Heikkinen, Janne Mannila, Jae Hoon Chang, +4 more
4citations -
Preparative Production of Functionalized (N- and O-Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor2022 Biomolecules article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Matic Srdič, Nico D. Fessner, Deniz Yıldız, Anton Glieder, Markus Spiertz, Ulrich Schwaneberg
7citations -
Discovering interactions in polypharmacy: Impact of metamizole on the metabolism of quetiapine2024 British Journal of Clinical Pharmacology article Biochemistry, Genetics and Molecular Biology Blood disorders and treatments Open access
Fabian Watermeyer, Arnim Johannes Gaebler, Irene Neuner, Ekkehard Haen, Christoph Hiemke, Georgios Schoretsanitis, +1 more
11citations -
Discovering Interactions in polypharmacy: Impact of Metamizole on the Metabolism of Quetiapine2023 preprint Biochemistry, Genetics and Molecular Biology Blood disorders and treatments Open access
Fabian Watermeyer, Arnim Johannes Gaebler, Irene Neuner, Ekkehard Haen, Christoph Hiemke, Georgios Schoretsanitis, +1 more
0citations -
Decreased concentrations of quetiapine in plasma of patients under co-medication with metamizole2023 preprint Biochemistry, Genetics and Molecular Biology Blood disorders and treatments Open access
Fabian Watermeyer, Arnim Johannes Gaebler, Irene Neuner, Ekkehard Haen, Christoph Hiemke, Georgios Schoretsanitis, +1 more
0citations -
The negative impact of vitamin D on antipsychotic drug exposure may counteract its potential benefits in schizophrenia2022 British Journal of Clinical Pharmacology article Medicine Vitamin D Research Studies Open access
Arnim Johannes Gaebler, Michelle Finner‐Prével, Sarah Edith Lammertz, Sabrina Schaffrath, Patrick D. Eisner, Felix Stöhr, +13 more
15citations -
Pharmacogenetic and drug interaction aspects on ketamine safety in its use as antidepressant ‐ implications for precision dosing in a global perspective2022 British Journal of Clinical Pharmacology article Medicine Treatment of Major Depression Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Julian Peter Müller, Julia Stingl
40citations -
Metamizole but not ibuprofen reduces the plasma concentration of sertraline: Implications for the concurrent treatment of pain and depression/anxiety disorders2020 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Arnim Johannes Gaebler, Georgios Schoretsanitis, Nagia Ben Omar, Ekkehard Haen, Katharina Endres, Christoph Hiemke, +1 more
11citations -
The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach2026 British Journal of Clinical Pharmacology article Computer Science Computational Drug Discovery Methods Open access
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, +3 more
0citations -
Preparative‐Scale Production of Testosterone Metabolites by Human Liver Cytochrome P450 Enzyme 3A42020 Advanced Synthesis & Catalysis article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Nico D. Fessner, Matic Srdič, Hansjörg Weber, Christian Schmid, David Schönauer, Ulrich Schwaneberg, +1 more
20citations -
Cover Feature: Natural Product Diversification by One‐Step Biocatalysis using Human P450 3A4 (ChemCatChem 1/2022)2021 ChemCatChem article Biochemistry, Genetics and Molecular Biology Steroid Chemistry and Biochemistry
Nico D. Fessner, Christopher Grimm, Matic Srdič, Hansjörg Weber, Wolfgang Kroutil, Ulrich Schwaneberg, +1 more
0citations -
218P Differential effects of estrogen exposure on steroid metabolizing CYP enzyme expression in estrogen receptor alpha versus beta positive breast cancer cell lines0citations
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Metabolic activation of WHO-congeners PCB28, 52, and 101 by human CYP2A6: evidence from in vitro and in vivo experiments2024 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Isabella Eva Randerath, Thomas Schettgen, Julian Peter Müller, Jens Rengelshausen, Susanne Maria Ziegler, Nathalia Quinete, +11 more
15citations
18 results