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Multi-omic profiling of human thymic B cells reveals intrathymic Ig-class switching and differentiation into multiple memory B cell subsets2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Martijn Cordes, Erik B. van den Akker, Janine E. Melsen, Saskia Bunschuh, Aline Zbinden, Sandra de Bruin-Versteeg, +8 more
0citations -
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation2021 EMBO Reports article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent
Muhammad Assad Aslam, Mir Farshid Alemdehy, Eliza Mari Kwesi‐Maliepaard, Marieta Cagánová, Iris N. Pardieck, Teun van den Brand, +9 more
45citations -
Restoration of T and B Cell Differentiation after RAG1 Gene Transfer in Human RAG1 Defective Hematopoietic Stem Cells2024 Biomedicines article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Nataël Sorel, Francisco Díaz-Pascual, Boris Bessot, Hanem Sadek, Chloé Mollet, Myriam Chouteau, +12 more
5citations -
Improving naive B cell isolation by absence of CD45RB glycosylation and CD27 expression in combination with BCR isotype2022 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Jana Koers, Sabrina Pollastro, Simon Tol, Ilse T. G. Niewold, Pauline A. van Schouwenburg, Niek de Vries, +1 more
4citations -
EOMES and IL-10 regulate anti-tumor activity of PD-1 + CD4 + T-cells in B-cell Non-Hodgkin lymphoma2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Philipp M. Roessner, Laura Llaó Cid, Ekaterina Lupar, Tobias Roider, Marie Bordas, Christoph Schifflers, +10 more
4citations -
FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation2022 Journal of Clinical Investigation article Medicine Systemic Lupus Erythematosus Research Open access
Ashley N. Barlev, Susan Malkiel, Izumi Kurata-Sato, Annemarie L Dorjée, Jolien Suurmond, Betty Diamond
30citations -
Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency2022 Frontiers in Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Pauline A. van Schouwenburg, Susanne Unger, Kathryn J. Payne, Fabian M. P. Kaiser, Ingrid Pico‐Knijnenburg, Jens Pfeiffer, +8 more
11citations -
Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation2023 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Aldo Spanjaard, Maria Stratigopoulou, Daniël de Groot, Muhammad Assad Aslam, Paul C.M. van den Berk, Chantal Stappenbelt, +7 more
2citations -
Generation of human induced pluripotent stem cell lines (LUMCi051-A,B and LUMCi052-A,B,C) of two patients with Spinocerebellar ataxia type 72024 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Linde F. Bouwman, Milou E.M. Joosen, Ronald A.M. Buijsen, Linda M. van der Graaf, Barry A. Pepers, Bas J. B. Voesenek, +3 more
3citations -
High Diversity of Glycosphingolipid Glycans of Colorectal Cancer Cell Lines Reflects the Cellular Differentiation Phenotype2022 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Di Wang, Katarina Madunić, Tao Zhang, Oleg A. Mayboroda, Guinevere S. M. Lageveen‐Kammeijer, Manfred Wuhrer
23citations -
Memory B cells dominate the early antibody-secreting cell response to SARS-CoV-2 mRNA vaccination in naïve individuals independently of their antibody affinity2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Zhe Li, Anna Obraztsova, Fuwei Shang, Opeyemi Ernest Oludada, Joshua Malapit, Katrin Busch, +4 more
0citations -
OP0243 SINGLE-CELL RNA SEQUENCING OF ACPA-ENRICHED B CELLS REVEALED A CD11c+ ATYPICAL B CELL GENE SIGNATURE IN RHEUMATOID ARTHRITIS2025 Annals of the Rheumatic Diseases conference-abstract Medicine Rheumatoid Arthritis Research and Therapies Open access
Yasuo Nagafuchi, Linda M. Slot, Deimantė Šimaitė, Aleida M. Bakker, Erik B. van den Akker, Tom W. J. Huizinga, +3 more
0citations -
Emerging Immune Cell Biomarkers in Primary Membranous Nephropathy: Immune Cell Profiling During Anti-CD20 B Cell-Targeted Therapy2026 International Journal of Molecular Sciences article Medicine Renal Diseases and Glomerulopathies Open access
Christos Georgopoulos, Eleni Stamellou, Αnila Duni, Lefkothea Dova, George Vartholomatos, Ekaterini C. Siomou, +2 more
0citations -
Stem-like PD-1 + TCF-1 + CD8 + T cells result from helpless priming and rely on CD4 + T-cell help to complete their cytotoxic effector differentiation2026 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology T-cell and B-cell Immunology Open access
Julia Busselaar, Douwe M. T. Bosma, Mo D. Staal, Xin Lei, Yanling Xiao, Jannie G. Borst
2citations -
Cell-of-origin classification using the Hans and Lymph2Cx algorithms in primary cutaneous large B-cell lymphomas2022 Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin article Medicine Cutaneous lymphoproliferative disorders research Open access
Anne M.R. Schrader, Ruben A. L. de Groen, Rein Willemze, Patty M. Jansen, Koen D. Quint, Tom van Wezel, +10 more
20citations -
Generation of 4 human induced pluripotent stem cell lines (LUMCi070-A, −B, −C, and −D) from a patient with ischemic cerebral small vessel disease2026 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Bas J. B. Voesenek, Linda M. van der Graaf, Saskia A.J. Lesnik Oberstein, Willeke M.C. van Roon-Mom, Elena Daoutsali, Ronald A.M. Buijsen
0citations -
Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity2023 Cellular and Molecular Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte‐Real, Ibrahim Hamad, Sam Vanherle, +16 more
65citations -
Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology T-cell and B-cell Immunology Open access
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte‐Real, Ibrahim Hamad, Mansour Haidar, +14 more
4citations