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Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches2024 Seminars in Immunology article Immunology and Microbiology Complement system in diseases Open access
Vitalijs Ovcinnikovs, Karin Dijkman, Gijs G. Zom, Frank J M Beurskens, Leendert Adrianus Trouw
18citations -
Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation2023 Proceedings of the National Academy of Sciences article Medicine Systemic Lupus Erythematosus Research Open access cited by 3 patents
Douwe J. Dijkstra, Fleur S. van de Bovenkamp, Leoni Abendstein, Rob Zuijderduijn, Jos Pool, Cynthia S. M. Kramer, +10 more
18citations -
Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through cell-mediated killing2024 Communications Biology article Immunology and Microbiology HIV Research and Treatment Open access
Steven W. de Taeye, Angela I. Schriek, Jeffrey C. Umotoy, Marloes Grobben, Judith A. Burger, Rogier W. Sanders, +5 more
17citations -
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study2025 Nature Communications article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Mitchell Emmers, Marij J.P. Welters, Michelle V. Dietz, Saskia J A M Santegoets, Sanne Boekesteijn, Anouk Stolk, +12 more
17citations -
YAP1 is essential for self-organized differentiation of pluripotent stem cells2023 Biomaterials Advances article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Kira Zeevaert, Roman Goetzke, Mohamed H. Elsafi Mabrouk, Catharina Maaßen, Ann-Christine Henneke, Chao He, +3 more
15citations -
C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8+ T cell homeostasis and response to acute liver injury2024 Hepatology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection
Patricia Maria Niemietz, Moritz Peiseler, Marlene Sophia Kohlhepp, Paul M. Horn, Kylie P. Matchett, Yuting Wang, +13 more
12citations -
Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data sets2024 Journal of Molecular and Cellular Cardiology article Medicine Cardiac Fibrosis and Remodeling Open access
Natasha de Winter, Jiahui Ji, Amalia Sintou, Elvira Forte, Michael Man-Kit Lee, Michela Noseda, +8 more
12citations -
A functional spleen contributes to afucosylated IgG in humans2021 Scientific Reports article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Iwona Wójcik, David E. Schmidt, Lisa A. de Neef, Minke A.E. Rab, Bob Meek, Okke de Weerdt, +6 more
10citations -
Comprehensive Immunoglobulin G, A, and M Glycopeptide Profiling for Large-Scale Biomedical Research2025 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Bianca D. M. van Tol, Anna Wasynczuk, Steinar Gijze, Oleg A. Mayboroda, Jan Nouta, R. Dolhain, +2 more
10citations -
Acetyl-CoA Carboxylase Inhibitor CP640.186 Increases Tubulin Acetylation and Impairs Thrombin-Induced Platelet Aggregation2021 International Journal of Molecular Sciences article Medicine Platelet Disorders and Treatments Open access
Marie Octave, Laurence Pirotton, Audrey Ginion, Valentine Robaux, Sophie Lepropre, Jérôme Ambroise, +7 more
10citations -
Discovery of a Novel Inner Membrane-Associated Bacterial Structure Related to the Flagellar Type III Secretion System2022 Journal of Bacteriology article Biochemistry, Genetics and Molecular Biology Advanced Electron Microscopy Techniques and Applications Open access
Mohammed Kaplan, Catherine M. Oikonomou, Cecily R. Wood, Georges Chreifi, Debnath Ghosal, Megan J. Dobro, +13 more
9citations -
Immunosenescence accelerates atherosclerosis development in AAV-PCSK9 mouse model2025 GeroScience article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Jill de Mol, Virginia Smit, Mireia N. A. Bernabé Kleijn, Peter J. van Santbrink, Ilze Bot, Amanda C. Foks
9citations -
A robust nanoscale RP HPLC-MS approach for sensitive Fc proteoform profiling of IgG allotypes2023 Analytica Chimica Acta article Medicine Monoclonal and Polyclonal Antibodies Research Open access
Constantin Blöchl, Christoph Gstöttner, Thomas Sénard, Eva Maria Stork, Hans Ulrich Scherer, René E. M. Toes, +2 more
8citations -
Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer2021 World Journal of Gastrointestinal Oncology article Biochemistry, Genetics and Molecular Biology PI3K/AKT/mTOR signaling in cancer Open access
Katharina Joechle, Jessica Guenzle, Claus Hellerbrand, Pavel Strnad, Thorsten Cramer, Ulf P. Neumann, +1 more
8citations -
Delayed vaccine-induced CD8+ T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication2023 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Tetje Cornelia van der Sluis, Floortje J. van Haften, Suzanne van Duikeren, Iris N. Pardieck, J. Fréderique de Graaf, Ward Vleeshouwers, +4 more
7citations