Papers matching “predictive toxicity models” 168
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Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors2021 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Huan Yang, Wanda van der Stel, Caroline Bauch, Sam Bevan, PAUL A. WALKER, Bob van de Water, +2 more
23citations -
Large-Scale Modeling of Sparse Protein Kinase Activity Data2023 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Sohvi Luukkonen, Erik Meijer, Giovanni A. Tricarico, Johan Hofmans, Pieter F. W. Stouten, Gerard J. P. van Westen, +1 more
14citations -
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology2021 Journal of Cheminformatics article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Xuhan Liu, Kai Ye, Herman van Vlijmen, Michael Emmerich, Adriaan P. IJzerman, Gerard J. P. van Westen
118citations -
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors2024 Environmental Health Perspectives article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marije Niemeijer, Witold Więcek, Shuai Fu, Suzanna Huppelschoten, Peter Bouwman, Audrey Baze, +5 more
16citations -
Exploring the Antimycobacterial Potential of Podocarpusflavone A from Kielmeyera membranacea: In Vitro and In Vivo Insights2024 Pharmaceuticals article Biochemistry, Genetics and Molecular Biology Biological Activity of Diterpenoids and Biflavonoids Open access
Marlon Heggdorne de Araújo, Salomé Muñoz Sánchez, Thatiana Lopes Biá Ventura Simão, Natalia Nowik, Stella Schuenck Antunes, Shaft Corrêa Pinto, +8 more
0citations -
Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based Virtual Screening2022 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Alzbeta Tuerkova, Brandon J. Bongers, Ulf Norinder, Orsolya Ungvári, Virág Székely, Andrey Tarnovskiy, +4 more
24citations -
Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Maral Baghai Arassi, Nicolai Karcher, Eleonora Mastrorilli, Matthias Groß, Amber Brauer-Nikonow, David Czock, +3 more
6citations -
Primary Cancer Matters in Therapy-related Myeloid Neoplasm Patients Receiving Allogeneic Hematopoietic Cell Transplantation: A Study From the Chronic Malignancies Working Party of the EBMT
Marie Robin, Liesbeth C. de Wreede, Thomas A. Schroeder, Friedrich Stölzel, Nicolaus Kröger, Linda Köster, +18 more
3citations -
Sequential pesticide exposure: Concentration addition at high concentrations - Inhibition of hormesis at ultra-low concentrations2024 The Science of The Total Environment article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Imrana Mushtaq, Naeem Shahid, Ayesha Siddique, Matthias Liess
3citations -
Safety, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary efficacy of AZD2936, a bispecific antibody targeting PD-1 and TIGIT, in checkpoint inhibitor (CPI)-experienced advanced/metastatic non-small-cell lung cancer (NSCLC): First report of ARTEMIDE-01.2023 Journal of Clinical Oncology conference-abstract Medicine Cancer Immunotherapy and Biomarkers Open access
Kristoffer Staal Rohrberg, Mariana Brandão, Eduardo Castañón Álvarez, Enriqueta Felip, Eelke Hiddo Gort, T. Jeroen N. Hiltermann, +14 more
22citations -
Structure over States: Planarity, Not Energy, Dictates Photoactivation in Ru(II) PACT Agents2025 Journal of the American Chemical Society article Chemistry Photochemistry and Electron Transfer Studies Open access
Matthijs L. A. Hakkennes, Irene Regeni, Yurii Husiev, Valeriia D. Andreeva, Maxime A. Siegler, Francesco Buda, +1 more
9citations