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Epicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathy2021 Science Translational Medicine article Medicine Cardiovascular Effects of Exercise Open access cited by 1 patent
Arwa Kohela, Sebastiaan J. van Kampen, Tara Moens, Martijn Wehrens, Bas Molenaar, Cornelis J.J. Boogerd, +6 more
45citations -
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression2020 Oncogene article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Jichao He, Ronan P. McLaughlin, Lambert van der Beek, Sander Canisius, Lodewyk F.A. Wessels, Marcel Smid, +4 more
44citations -
Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease cathepsin S2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Tom J. Harryvan, Marten Visser, Linda de Bruin, Leonie G Plug, Lisa Griffioen, Arend Mulder, +12 more
42citations -
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling2021 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Kim van Kuijk, Jasper A. F. Demandt, Javier Perales-Patón, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, +13 more
40citations -
ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells2024 Journal of Experimental & Clinical Cancer Research article Medicine Drug Transport and Resistance Mechanisms Open access
Cecilia Bergonzini, Alessandro Gregori, Tessa M. S. Hagens, Vera E. van der Noord, Bob van de Water, Annelien J.M. Zweemer, +10 more
38citations -
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells2020 Journal of Cellular and Molecular Medicine article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Tanzeela Awan, Aaron Babendreyer, Abid Mahmood Alvi, Stefan Düsterhöft, Daniela Lambertz, Jörg Walter Bartsch, +2 more
37citations -
Prognostic Significance of Integrin Subunit Alpha 2 (ITGA2) and Role of Mechanical Cues in Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma (PDAC)
Alessandro Gregori, Cecilia Bergonzini, Mjriam Capula, Giulia Mantini, Fatemeh Khojasteh‐Leylakoohi, Annalisa Comandatore, +7 more
36citations -
An antisense noncoding RNA enhances translation via localized structural rearrangements of its cognate mRNA2021 The Plant Cell article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Rodrigo Siqueira Reis, Jules Deforges, Romy Schmidt, Jos H. M. Schippers, Yves Poirier
33citations -
Stabilization of desmoglein-2 binding rescues arrhythmia in arrhythmogenic cardiomyopathy2020 JCI Insight article Medicine Cardiac electrophysiology and arrhythmias Open access cited by 2 patents
Camilla Schinner, Bernd Markus Erber, Sunil Yeruva, Angela Schlipp, Vera Rötzer, Ellen Kempf, +4 more
31citations -
VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis2020 Cells article Biochemistry, Genetics and Molecular Biology Nuclear Structure and Function Open access
Daniel Moreno-Andrés, Hideki Yokoyama, Anja Scheufen, Guillaume Holzer, Hongqi Lue, Anna Katharina Schellhaus, +3 more
30citations -
SLC44A2 deficient mice have a reduced response in stenosis but not in hypercoagulability driven venous thrombosis2020 Journal of Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Julia Tilburg, Daniëlle M. Coenen, Gaïa Zirka, Sophie Dólleman, Annemarie M. van Oeveren‐Rietdijk, Mieke F.A. Karel, +7 more
27citations -
Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation2020 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Simon Dirmeier, Christopher Dächert, Martijn J. van Hemert, Ali Taş, Natacha S. Ogando, Frank J. M. van Kuppeveld, +4 more
23citations -
IFNɣ but not IFNα increases recognition of insulin defective ribosomal product-derived antigen to amplify islet autoimmunity2023 Diabetologia article Biochemistry, Genetics and Molecular Biology Diabetes and associated disorders Open access
Sofia Thomaidou, Amadeo Munoz-Garcia, Sabine de Lange, Arno R. van der Slik, Rob C. Hoeben, Bart O. Roep, +2 more
18citations -
NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA2022 Antioxidants article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Anandhi Rajendiran, Sudheendra Hebbar Subramanyam, Patricia Klemm, Vera Jankowski, Jorg van Loosdregt, Sebastiaan J. Vastert, +4 more
16citations -
Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes2021 Cell Biology and Toxicology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Lukas S. Wijaya, Carina Rau, Theresa Braun, Serif Marangoz, Vincent Spegg, Matthijs Vlasveld, +8 more
15citations -
Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice2020 Skeletal Muscle article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Linde F. Bouwman, Bianca den Hamer, Elwin P. Verveer, Lente J. S. Lerink, Yvonne D. Krom, Silvère M. van der Maarel, +1 more
13citations -
RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair2021 Cell Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Yoko Katsuki, Masako Abe, Seon Young Park, Wenwen Wu, Hiromasa Yabe, Miharu Yabe, +6 more
13citations -
Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells2021 Molecular Human Reproduction article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling
Annika Missel, Lena Walenta, Katja Eubler, Nadine Mundt, Hanna Heikelä, Ulrich Pickl, +8 more
13citations