Papers matching “predictive toxicity models” 126
Not finding it? Sign in to also search OpenAlex live.
-
Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations -
Low Tacrolimus C0/Dose Ratio is Associated with Higher Cmax and AUC Despite Similar Pre-dose Concentrations2026 Clinical Pharmacokinetics article Medicine Renal Transplantation Outcomes and Treatments Open access
Amar D. Levens, Teun van Gelder, Armin Gelinck, Soufian Meziyerh, Aiko P. J. de Vries, Danny van der Helm, +2 more
0citations -
The Changing Face of Oncology Research, Drug Development, and Clinical Practice: Toward Patient‐Focused Precision Therapeutics2020 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access
Karthik Venkatakrishnan, Piet H. van der Graaf, Sarah A. Holstein
4citations -
Bioavailability and phytotoxicity of rare earth metals to Triticum aestivum under various exposure scenarios2020 Ecotoxicology and Environmental Safety article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Erkai He, Bing Xia, Rongrong Ying, Willie J.G.M. Peijnenburg, Yang Liu, Hao Qiu
19citations -
Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans2024 Archives of Toxicology article Computer Science Computational Drug Discovery Methods Open access
René Geci, Domenico Gadaleta, Marina García de Lomana, Rita Ortega-Vallbona, Erika Colombo, Eva Serrano‐Candelas, +3 more
33citations -
Hydrogen sulfide as a therapeutic gas: challenges and opportunities in precision medicine2026 Medical Gas Research article Biochemistry, Genetics and Molecular Biology Sulfur Compounds in Biology Open access
Okechukwu Paul-Chima Ugwu, Esther Ugo Alum, Val Hyginus Udoka Eze, Mariam Basajja
0citations -
Evaluating chemical similarity as a measure to identify potential substances of very high concern2020 Regulatory Toxicology and Pharmacology article Computer Science Computational Drug Discovery Methods Open access
Pim N.H. Wassenaar, Emiel Rorije, Martina G. Vijver, Willie J.G.M. Peijnenburg
19citations -
P537: SAFETY AND TOLERABILITY OF AZD0466 AS MONOTHERAPY FOR PATIENTS WITH ADVANCED HEMATOLOGICAL MALIGNANCIES - PRELIMINARY RESULTS FROM AN ONGOING PHASE I/II TRIAL2023 HemaSphere article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Giovanni Marconi, Shukaib Arslan, Shaun A. Fleming, Antonio Curti, James Stewart Blachly, Giovanni Martinelli, +15 more
0citations -
Albuminuria or proteinuria in glomerular disease and CKD—which one to use?2026 Nephrology Dialysis Transplantation article Medicine Chronic Kidney Disease and Diabetes Open access
Vanja Ivković, Andreas Kronbichler, Chee Kay Cheung, Jonathan Barratt, Annette N. Bruchfeld, Jürgen Floege, +1 more
1citations -
Integrating human exposome data into next-generation risk assessment: a systematic framework to infer real-life exposure levels and prioritize chemical compounds for testing2026 Environment International article Environmental Science Health, Environment, Cognitive Aging Open access
Yifeng Dai, Bob van de Water, Jaione Telleria, Laura Ines Furlong, Roel C.H. Vermeulen, Jelle J. Vlaanderen
1citations -
Towards a quantitative adverse outcome pathway for liver carcinogenesis: From proliferation to prediction2025 Computational Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Christina H. J. Veltman, Hiba Khalidi, Elias Zgheib, Bob van de Water, Mirjam Luijten, Jeroen L. A. Pennings
1citations -
Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors2021 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Huan Yang, Wanda van der Stel, Caroline Bauch, Sam Bevan, PAUL A. WALKER, Bob van de Water, +2 more
23citations -
Large-Scale Modeling of Sparse Protein Kinase Activity Data2023 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Sohvi Luukkonen, Erik Meijer, Giovanni A. Tricarico, Johan Hofmans, Pieter F. W. Stouten, Gerard J. P. van Westen, +1 more
14citations -
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology2021 Journal of Cheminformatics article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Xuhan Liu, Kai Ye, Herman van Vlijmen, Michael Emmerich, Adriaan P. IJzerman, Gerard J. P. van Westen
118citations -
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors2024 Environmental Health Perspectives article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marije Niemeijer, Witold Więcek, Shuai Fu, Suzanna Huppelschoten, Peter Bouwman, Audrey Baze, +5 more
16citations