Papers matching “predictive toxicity models” 166
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Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials2025 Environmental Science & Technology article Materials Science Nanoparticles: synthesis and applications Open access
Laura Aliisa Saarimäki, Michele Fratello, Giusy del Giudice, Emanuele Di Lieto, Antreas Afantitis, Harri Tapio Alenius, +21 more
3citations -
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers2025 Environment International article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Fabian G. Weichert, Pedro A. Inostroza, Jörg Ahlheim, Thomas Backhaus, Werner Brack, Mario Brauns, +4 more
15citations -
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Environmental Science Environmental Toxicology and Ecotoxicology Open access
Fabian G. Weichert, Pedro A. Inostroza, Jörg Ahlheim, Thomas Backhaus, Werner Brack, Mario Brauns, +4 more
0citations -
Computational modelling identifies primary mediators of crosstalk between DNA damage and oxidative stress responses2025 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Elsje J Burgers, Raju P. Sharma, Carl Joshua Eugenio, Muriel M. Heldring, Lukas S. Wijaya, Bob van de Water, +1 more
3citations -
Double trouble: The synergistic threat of environmental stressors and pesticide mixtures2025 Journal of Hazardous Materials article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Naeem Shahid, Ayesha Siddique, Martin Krayer Von Krauss, Alexander Böhme, Werner Brack, Annika Jahnke, +1 more
9citations -
Safety and Tolerability of AZD0466 As Monotherapy for Patients with Advanced Hematologic Malignancies. Results from a Phase I/II Trial2023 Blood conference-abstract Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation
Shukaib Arslan, Giovanni Marconi, Giovanni Martinelli, Shaun A. Fleming, Antonio Curti, Shira Naomi Dinner, +19 more
5citations -
Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes2020 BMC Bioinformatics article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert C. J. J. Passier
14citations -
Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach2025 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Martijn L. Manson, Anne‐Grete Märtson, Jacob Bodilsen, Elizabeth C. M. de Lange
3citations -
Prediction of dose reductions and impact of reduced starting doses of CDK4 /6i on effectiveness in HR ‐positive/ HER2 ‐negative metastatic breast cancer: Real‐world data from the OPAL registry
Patrick Marschner, Kai G. Ringwald, Marc Thill, Mark‐Oliver Zahn, Anja Welt, Arnd Nusch, +14 more
4citations -
In Search of Beautiful Molecules: A Perspective on Generative Modeling for Drug Design2025 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Remco L. van den Broek, Shivam Patel, Gerard J. P. van Westen, Willem Jespers, Woody Sherman
38citations -
Breast Cancer Index Predicts Extended Endocrine Benefit to Individualize Selection of Patients with HR+ Early-stage Breast Cancer for 10 Years of Endocrine Therapy2020 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access cited by 1 patent
Iris Noordhoek, Kai Treuner, Hein Putter, Yi Zhang, Jenna Wong, Elma Meershoek‐Klein Kranenbarg, +4 more
133citations -
A simplified co-culture reveals altered cardiotoxic responses to doxorubicin in hPSC-derived cardiomyocytes in the presence of endothelial cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
Marcella Brescia, Andrea Chatrian, Paul Keselman, James Gallant, Elsa Sorman Paulsson, Mervyn P.H. Mol, +10 more
1citations -
Data from Breast Cancer Index Predicts Extended Endocrine Benefit to Individualize Selection of Patients with HR+ Early-stage Breast Cancer for 10 Years of Endocrine Therapy
Iris Noordhoek, Kai Treuner, Hein Putter, Yi Zhang, Elma Meershoek‐Klein Kranenbarg, Marjolijn Duijm‐de Carpentier, +3 more
0citations -
Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing2020 Clinical Pharmacokinetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anyue Yin, Madeleine H. T. Ettaieb, Jesse Joachim Swen, Liselotte van Deun, Thomas M. A. Kerkhofs, R.J.H.M. van der Straaten, +11 more
13citations -
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies2021 Journal of Pharmaceutical Sciences article Engineering 3D Printing in Biomedical Research Open access
Marianne K. Vormann, Jelle Vriend, Henriëtte L. Lanz, Linda Gijzen, Angelique van den Heuvel, Simon Hutter, +17 more
88citations -
Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction2021 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access cited by 1 patent
Wesley Huisman, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, J.H. Frederik Falkenburg, +1 more
19citations