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The lncRNA LETS1 promotes TGF-β–induced EMT and cancer cell migration by transcriptionally activating a TβR1-stabilizing mechanism2023 Science Signaling article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Chuannan Fan, Román González‐Prieto, Thomas B. Kuipers, Alfred C.O. Vertegaal, Peter A. van Veelen, Hailiang Mei, +1 more
30citations -
A solid beta-sheet structure is formed at the surface of FUS liquid droplets during aging2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Amyotrophic Lateral Sclerosis Research Open access
Leonidas Emmanouilidis, Ettore Bartalucci, Yelena Kan, Mahdiye Ijavi, Maria Escura Pérez, Pavel Afanasyev, +7 more
13citations -
PAF1C restores transcription after DNA damage independently of promoting histone mark deposition2026 EMBO Reports article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Janne J. M. van Schie, Bram A F J de Groot, Diana van den Heuvel, Martijn S. Luijsterburg
2citations -
PUMA-induced apoptosis drives bone marrow failure and genomic instability in telomerase-deficient mice2025 Cell Death and Differentiation article Medicine Telomeres, Telomerase, and Senescence Open access
Christian Molnár, Jovana Rajak, Julia Miriam Weiss, Irene González-Menéndez, Geoffroy Andrieux, Franziska Schreiber, +14 more
1citations -
lncRNA-based prognostic model for pancreatic cancer centered on the TME with exploratory LLPS connections2026 Frontiers in Oncology article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Yaqing Wei, Xiguang Sun, Yifei Wang, Zheran Lu, Chenhui Zhang, Hao Yao, +1 more
0citations -
Fabry Disease: Molecular Basis, Pathophysiology, Diagnostics and Potential Therapeutic Directions2021 Biomolecules article Medicine Lysosomal Storage Disorders Research Open access cited by 1 patent
Ken Kok, Kimberley C. Zwiers, Rolf G. Boot, Herman S. Overkleeft, Johannes M. F. G. Aerts, Marta Artola
131citations -
High-yield on-demand production of tobacco mosaic virus-like particles using a plant-derived cell-free expression system2025 Frontiers in Nanotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access
David H. B. Große, Eva Miriam Buhl, Alexander Croon, Stefan Schillberg, Juliane Schuphan
2citations -
Production and Storage of High-Capacity Adenoviral Vectors for the Delivery of Advanced CRISPR Systems2026 Methods in molecular biology book-chapter Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Xiaoling Wang, Jin Liu, Josephine M. Janssen, Manuel A.F.V. Gonçalves
0citations -
Optimization of Targeted Lipid Nanoparticle for the Treatment of RUNX1::ETO Driven AML2024 Blood conference-abstract Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
L. Daniel Mata Casimiro, Manisha du Plessis, Dennis Unthan, Heyang Zhang, Matthias Barz, Raymond Michel Schiffelers, +1 more
2citations -
Polysarcosine-based lipid formulations for intracranial delivery of mRNA2023 Journal of Controlled Release article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 3 patents
Dongdong Bi, Dennis Unthan, Jeroen Bussmann, Katrien Remaut, Matthias Barz, Heyang Zhang
46citations -
Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia2021 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Samoil Sekulovski, Pascal Devant, Silvia Panizza, Tasos Gogakos, Anda Pitiriciu, Katharina Heitmeier, +8 more
39citations -
Impact of Stimuli-Responsiveness on the mRNA Delivery Efficiency of Low-Generation Dendrimer Nanogels2025 Biomacromolecules article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Xianghao Xiao, Yue Gao, Yiyang Jia, Mingwu Shen, Andrij Pich, Xiangyang Shi
10citations -
A single-nucleotide change in the Kozak sequence enhances protein expression2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Renzo A. Knol, Tahmina Fariaby, Eveline A. de Vlieger, Alexander Kros, Bram Slütter
0citations -
An adeno-associated virus gene therapy strategy for anti-obesity treatment by nanocarrier-based delivery systems2025 Journal of Nanobiotechnology article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Li Li, Wang Wang, Rong Li, Jiayue Guo, Xulin Hu, Yu Pan, +6 more
4citations -
LAH5-mediated delivery of prime editor ribonucleoprotein complexes for genome editing2026 International Journal of Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Bing Yao, Mert Öktem, Qian Wang, Mark A. Daniels, Inge Dokter, Juliet W. Lefferts, +7 more
2citations -
Abstract 2714: Developing an mRNA encoded therapeutic antibody platform to simplify manufacturing and reduce time to clinic2024 Cancer Research conference-abstract Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Roxana Simona Redis, Dan Rocca, Rachel Pooley, Namrata Jayanth, Eva Oswald, Alexander Hale, +2 more
1citations -
Using muscle homing peptide CyPep10 to deliver phosphorodiamidate morpholino oligomers in the mdx mouse2025 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Anne-Fleur E. Schneider, Christa L. Tanganyika-de Winter, Silvana M.G. Jirka, Xuyu Tan, Emily G. Thompson, Kristen Ha, +4 more
1citations