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The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment2021 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulia Callegaro, Steven J. Kunnen, Panuwat Trairatphisan, Solène Grosdidier, Marije Niemeijer, Wouter den Hollander, +9 more
43citations -
On genetic programming representations and fitness functions for interpretable dimensionality reduction2022 Genetic and Evolutionary Computation Conference (GECCO) conference-paper Computer Science Evolutionary Algorithms and Applications Open access
Thomas Uriot, Marco Virgolin, Tanja Alderliesten, Peter A. N. Bosman
18citations -
The role of the estimand framework in the analysis of patient-reported outcomes in single-arm trials: a case study in oncology2024 BMC Medical Research Methodology article Mathematics Statistical Methods in Clinical Trials Open access
Doranne Thomassen, Satrajit Roychoudhury, Cecilie Delphin Amdal, Dries Reynders, Jammbe Z. Musoro, Willi Sauerbrei, +32 more
13citations -
PhenoScore: AI-based phenomics to quantify rare disease and genetic variation2022 medRxiv preprint Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases Open access
Alexander J.M. Dingemans, Max Hinne, Kim M. G. Truijen, Lia C. M. J. Goltstein, Jeroen van Reeuwijk, Nicole de Leeuw, +25 more
6citations -
Development and evaluation of regression tree models for predicting in-hospital mortality of a national registry of COVID-19 patients over six pandemic surges2024 BMC Medical Informatics and Decision Making article Medicine COVID-19 Clinical Research Studies Open access
Martijn C. Schut, Dave Anton Dongelmans, Dylan W. de Lange, Sylvia Brinkman, D.P. Verbiest, Leo F te Velde, +66 more
5citations -
Cell type heterogeneity in gene co-expression networks: implications for toxicological research2025 Briefings in Bioinformatics review Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Imke B. Bruns, Yingxue Li, James L. Stevens, Bob van de Water, Giulia Callegaro
5citations -
Assessing and improving the validity of COVID-19 autopsy studies - a multicenter approach to establish essential standards for immunohistochemical and ultrastructural analyses
Susanne Krasemann, Carsten Dittmayer, Saskia Freifrau von Stillfried, Jenny Meinhardt, Fabian Heinrich, Katrin Hartmann, +26 more
3citations -
The human hepatocyte TXG-MAPr: WGCNA transcriptomic modules to support mechanism-based risk assessment2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulia Callegaro, Steven J. Kunnen, Panuwat Trairatphisan, Solène Grosdidier, Marije Niemeijer, Wouter den Hollander, +9 more
1citations