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Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol2023 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Kim van Kuijk, Ian R McCracken, Renée J. H. A. Tillie, S. Asselberghs, Dlzar Ali Kheder, Stan Muitjens, +22 more
48citations -
Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease2021 Frontiers in Genetics article Medicine Celiac Disease Research and Management Open access cited by 1 patent
Adriaan van der Graaf, Maria Magdalena Zorro, Annique Claringbould, Urmo Võsa, Raúl Aguirre‐Gamboa, Chan Li, +13 more
48citations -
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype2023 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christiaan H. Arendzen, +4 more
46citations -
Enzyme-Constrained Models and Omics Analysis of Streptomyces coelicolor Reveal Metabolic Changes that Enhance Heterologous Production2020 iScience article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Snorre Sulheim, Tjaša Kumelj, Dino van Dissel, Ali Salehzadeh‐Yazdi, Chao Du, Kay Nieselt, +3 more
46citations -
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation2021 EMBO Reports article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent
Muhammad Assad Aslam, Mir Farshid Alemdehy, Eliza Mari Kwesi‐Maliepaard, Marieta Cagánová, Iris N. Pardieck, Teun van den Brand, +9 more
45citations -
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study2021 Journal of the American Society of Nephrology article Medicine Chronic Kidney Disease and Diabetes Open access
Pamela R. Matías‐García, Rory Wilson, Qi Guo, Shaza B. Zaghlool, James Eales, Xiaoguang Xu, +31 more
45citations -
The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids2023 Communications Biology article Biochemistry, Genetics and Molecular Biology Plant biochemistry and biosynthesis Open access
Emily Amor Stander, Beata Joanna Lehka, Inês Carqueijeiro, Clément Cuello, Frederik G. Hansson, Hans J. Jansen, +17 more
45citations -
A hybrid-capture approach to reconstruct the phylogeny of Scleractinia (Cnidaria: Hexacorallia)2023 Molecular Phylogenetics and Evolution article Environmental Science Coral and Marine Ecosystems Studies Open access
Z.B. Randolph Quek, Sudhanshi S. Jain, Zoe T. Richards, Roberto Arrigoni, Francesca Benzoni, Bert Willem Hoeksema, +7 more
44citations -
Single‐cell omics: Overview, analysis, and application in biomedical science2021 Journal of Cellular Biochemistry article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Catarina M. Stein, Ralf Weiskirchen, Frédérik Damm, Paulina M. Strzelecka
43citations -
Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance2022 npj Breast Cancer article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Marlous Hoogstraat, Esther H. Lips, Isabel Mayayo‐Peralta, Lennart Mulder, Petra Kristel, Ingrid van der Heijden, +7 more
41citations -
Extracellular Vesicles May Predict Response to Radioembolization and Sorafenib Treatment in Advanced Hepatocellular Carcinoma: An Exploratory Analysis from the SORAMIC Trial2022 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Timothy Wai Ho Shuen, Marianna Alunni‐Fabbroni, Elif Öcal, Peter Malfertheiner, Moritz Wildgruber, Regina Schinner, +8 more
40citations -
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Karin D. Prummel, Helena Lucia Crowell, Susan Nieuwenhuize, Eline Constance Brombacher, Stephan Daetwyler, Charlotte Soneson, +17 more
39citations -
Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier2021 Journal of the American Society of Nephrology article Medicine Renal Diseases and Glomerulopathies Open access
Annika Möller‐Kerutt, Juan Eduardo Rodriguez-Gatica, Karin Wacker, Rohan Bhatia, Jan Peter Siebrasse, Nanda Boon, +6 more
38citations -
A comprehensive mouse kidney atlas enables rare cell population characterization and robust marker discovery2023 iScience article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Claudio Novella-Rausell, Magda Grudniewska, Dorien J.M. Peters, Ahmed Essam Mahfouz
38citations -
Phenotype-Agnostic Molecular Subtyping of Neurodegenerative Disorders: The Cincinnati Cohort Biomarker Program (CCBP)2020 Frontiers in Aging Neuroscience article Medicine Dementia and Cognitive Impairment Research Open access
Andrea Sturchio, Luca Marsili, Joaquín A. Vizcarra, Alok Kumar Dwivedi, Marcelo Andrés Kauffman, Andrew P. Duker, +18 more
38citations -
ABCB1 overexpression through locus amplification represents an actionable target to combat paclitaxel resistance in pancreatic cancer cells2024 Journal of Experimental & Clinical Cancer Research article Medicine Drug Transport and Resistance Mechanisms Open access
Cecilia Bergonzini, Alessandro Gregori, Tessa M. S. Hagens, Vera E. van der Noord, Bob van de Water, Annelien J.M. Zweemer, +10 more
38citations -
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification2022 Clinical and Translational Medicine article Medicine Parathyroid Disorders and Treatments Open access
Nikolaos Taxiarchis Skenteris, Till Seime, Anna Witasp, Eva Karlöf, Grzegorz B. Wasilewski, Marina Augusto Heuschkel, +18 more
37citations -
Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits2022 Communications Biology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Ernesto Rodríguez, Kelly Boelaars, Katarina Madunić, Thomas van Ee, Frederike Dijk, Joanne Verheij, +15 more
37citations