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EXTH-55. ALL-IN-ONE GENETIC CONSTRUCT TO KNOCKDOWN MIR-21 REDUCES GLIOMA PROLIFERATION IN VITRO2023 Neuro-Oncology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lisa Nieland, Anne B. Vrijmoet, Alexandra J E M de Reus, Benjamin Kleinsteiver, Marike L. D. Broekman, Xandra O. Breakefield, +1 more
1citations -
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro2022 Frontiers in Genetics article Medicine Cutaneous lymphoproliferative disorders research Open access
Eliza Mari Kwesi‐Maliepaard, Muddassir Malik, Tibor van Welsem, Remco van Doorn, Maarten H. Vermeer, Hanneke Vlaming, +2 more
3citations -
Abstract 2714: Developing an mRNA encoded therapeutic antibody platform to simplify manufacturing and reduce time to clinic2024 Cancer Research conference-abstract Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Roxana Simona Redis, Dan Rocca, Rachel Pooley, Namrata Jayanth, Eva Oswald, Alexander Hale, +2 more
1citations -
GRHL2 Regulation of Growth/Motility Balance in Luminal versus Basal Breast Cancer2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Zi Wang, Bircan Coban, Chen‐Yi Liao, Qiuyu Liu, Erik H.J. Danen
10citations -
Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression2023 Frontiers in Immunology article Immunology and Microbiology Mast cells and histamine Open access
Sandro Capellmann, Herdit M. Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, +4 more
6citations -
Transformation of primary murine peritoneal mast cells by constitutive KIT activation as a result of lost Cdkn2a/Arf expression2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Mast cells and histamine Open access
Sandro Capellmann, Herdit M. Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, +4 more
0citations -
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology2022 Journal of Medicinal Chemistry article Neuroscience Genetic Neurodegenerative Diseases Open access
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca E. Jarvis, Wesley Blackaby, Ovadia Lazari, +19 more
34citations -
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation2023 Cellular and Molecular Gastroenterology and Hepatology article Medicine Liver physiology and pathology Open access
Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, +12 more
27citations -
Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma2022 Investigative Ophthalmology & Visual Science article Medicine Ocular Oncology and Treatments Open access
Kseniya Glinkina, Fariba Némati, Amina F.A.S. Teunisse, Maria Chiara Gelmi, Muriel J. Kuipers, Samar Alsafadi, +3 more
6citations -
The Plasmodium falciparum CCCH zinc finger protein ZNF4 plays an important role in gametocyte exflagellation through the regulation of male gametocyte enriched transcripts2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Malaria Research and Control Open access
Borja Hanhsen, Afia Farrukh, Gabriele Pradel, Che Julius Ngwa
6citations -
Abstract 3794: Developing an mRNA nanomedicine platform to democratise therapeutic antibodies2025 Cancer Research conference-abstract Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Dan Rocca, Roxana Simona Redis, Phillipp Meyer, Ina Rohleff, Eva Oswald, Rachel Pooley, +6 more
2citations -
Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion2026 Nature Communications article Immunology and Microbiology Parasites and Host Interactions Open access
Wannaporn Ittiprasert, Michael J. Smout, Victoria H. Mann, Matthew Moyle, Sean Kinahan, Daniel N. Ackerman, +20 more
0citations -
Abstract 542: T-cell engager bispecific formats of an AML patient-derived antibody targeting a unique sialylated CD43 epitope induce kill of melanoma cells in vitro and in vivo
Greta de Jong, Lina Bartels, Martijn Kedde, Els M.E. Verdegaal, Marijn Aletta Gillissen, Sophie E. Levie, +13 more
0citations -
Combination of AFP vaccine and immune checkpoint inhibitors slows hepatocellular carcinoma progression in preclinical models2023 Journal of Clinical Investigation article Medicine Cancer Immunotherapy and Biomarkers Open access
Xinjun Lu, Jiejie Xu, Benjamin L. Green, Honghua Zhang, Guofei Cui, Yi Zhang, +10 more
40citations -
Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Karin D. Prummel, Helena Lucia Crowell, Susan Nieuwenhuize, Eline Constance Brombacher, Stephan Daetwyler, Charlotte Soneson, +17 more
39citations