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EXTH-55. ALL-IN-ONE GENETIC CONSTRUCT TO KNOCKDOWN MIR-21 REDUCES GLIOMA PROLIFERATION IN VITRO2023 Neuro-Oncology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lisa Nieland, Anne B. Vrijmoet, Alexandra J E M de Reus, Benjamin Kleinsteiver, Marike L. D. Broekman, Xandra O. Breakefield, +1 more
1citations -
Regulation of KIF23 by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2024 Journal of Hepatology article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Angendohr, Rossella Pellegrino, Mihael Vucur, Veronika Buettner, Matthias A. Dille, +14 more
11citations -
A perspective on causality assessment in epigenetic research on neurodegenerative disorders2022 Neural Regeneration Research article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Philippos Koulousakis, Assia Tiane, Niels Hellings, Jos Prickaerts, Daniël van den Hove, Tim Vanmierlo
8citations -
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia2022 Science Translational Medicine article Medicine CAR-T cell therapy research Open access cited by 2 patents
Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Annie Etuk, +52 more
204citations -
Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunity2025 Molecular Therapy article Medicine Glioma Diagnosis and Treatment Open access cited by 1 patent
Taral R. Lunavat, Lisa Nieland, Sanne M. van de Looij, Alexandra J E M de Reus, Charles Couturier, Chadi A. El Farran, +18 more
7citations -
Generation of LUMCi041-A-2: Equipping a PAX3 reporter iPSC line with doxycycline inducible H2B-mTurquoise2 for live cell imaging2021 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Christiaan H. Arendzen, Steve J. Cramer, Christian M.A.H. Freund, Christine L. Mummery, Adrian Ranga, Olivier Pourquié, +1 more
1citations -
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype2023 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christiaan H. Arendzen, +4 more
46citations -
Hurdles to the Adoption of Gene Therapy as a Curative Option for Transfusion-Dependent Thalassemia2022 Stem Cells Translational Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Isabelle Thuret, Annalisa Ruggeri, Emanuele Angelucci, Christian Chabannon
20citations -
Degenerated Cones in Cultured Human Retinas Can Successfully Be Optogenetically Reactivated2020 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Sizar Kamar, Marcus H. C. Howlett, Wim de Graaff, Tamás Csikós, Martijn J. W. E. Rabelink, Rob C. Hoeben, +1 more
9citations -
Generation of human induced pluripotent stem cell lines (LUMCi051-A,B and LUMCi052-A,B,C) of two patients with Spinocerebellar ataxia type 72024 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Linde F. Bouwman, Milou E.M. Joosen, Ronald A.M. Buijsen, Linda M. van der Graaf, Barry A. Pepers, Bas J. B. Voesenek, +3 more
3citations -
Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice2023 npj Vaccines article Medicine Tuberculosis Research and Epidemiology Open access cited by 1 patent
Sam Afkhami, Michael R. D’Agostino, Maryam Vaseghi‐Shanjani, Madeleine Lepard, Jack X. Yang, Rocky Lai, +8 more
26citations -
Mortality Prediction in Severe Traumatic Brain Injury Using Traditional and Machine Learning Algorithms2023 Journal of Neurotrauma article Medicine Traumatic Brain Injury and Neurovascular Disturbances Open access
Xiang Wu, Xiao Li Xu, Ewout Willem Steyerberg, Isabel Retel Helmrich, Fiona Elizabeth Lecky, Jianying Guo, +6 more
33citations