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Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Tumour-educated platelets for breast cancer detection: biological and technical insights2023 British Journal of Cancer article Biochemistry, Genetics and Molecular Biology Gene expression and cancer classification Open access
Marte C. Liefaard, Kat S Moore, Lennart Mulder, Daan van den Broek, Jelle Wesseling, Gabe S. Sonke, +3 more
27citations -
Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy E. van den Akker, David G.P. van IJzendoorn, Harald M. M. Mikkers, +5 more
3citations -
Genome-enabled insights into the biology of thrips as crop pests2020 BMC Biology article Biochemistry, Genetics and Molecular Biology Insect Resistance and Genetics Open access
Dorith Rotenberg, Aaron A. Baumann, Sulley K. Ben-Mahmoud, Olivier Christiaens, Wannes Dermauw, Panagiotis Ioannidis, +51 more
106citations -
Genome-enabled insights into the biology of thrips as crop pests2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Insect Resistance and Genetics Open access
Dorith Rotenberg, Aaron A. Baumann, Sulley K. Ben-Mahmoud, Olivier Christiaens, Wannes Dermauw, Panagiotis Ioannidis, +50 more
15citations -
EXTH-55. ALL-IN-ONE GENETIC CONSTRUCT TO KNOCKDOWN MIR-21 REDUCES GLIOMA PROLIFERATION IN VITRO2023 Neuro-Oncology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lisa Nieland, Anne B. Vrijmoet, Alexandra J E M de Reus, Benjamin Kleinsteiver, Marike L. D. Broekman, Xandra O. Breakefield, +1 more
1citations -
Intratumoral gene delivery of 4-1BBL boosts IL-12-triggered anti-glioblastoma immunity2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Taral R. Lunavat, Lisa Nieland, Sanne M. van de Looij, Alexandra J E M de Reus, Charles Couturier, Chadi A. El Farran, +18 more
0citations -
Regulation of KIF23 by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2024 Journal of Hepatology article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Angendohr, Rossella Pellegrino, Mihael Vucur, Veronika Buettner, Matthias A. Dille, +14 more
11citations -
KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Lohr, Rossella Pellegrino, Mihael Vucur, Michael T. Singer, Veronika Buettner, +7 more
0citations -
A perspective on causality assessment in epigenetic research on neurodegenerative disorders2022 Neural Regeneration Research article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Philippos Koulousakis, Assia Tiane, Niels Hellings, Jos Prickaerts, Daniël van den Hove, Tim Vanmierlo
8citations -
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia2022 Science Translational Medicine article Medicine CAR-T cell therapy research Open access cited by 2 patents
Giorgio Ottaviano, Christos Georgiadis, Soragia Athina Gkazi, Farhatullah Syed, Hong Zhan, Annie Etuk, +52 more
204citations -
Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunity2025 Molecular Therapy article Medicine Glioma Diagnosis and Treatment Open access cited by 1 patent
Taral R. Lunavat, Lisa Nieland, Sanne M. van de Looij, Alexandra J E M de Reus, Charles Couturier, Chadi A. El Farran, +18 more
7citations -
Generation of LUMCi041-A-2: Equipping a PAX3 reporter iPSC line with doxycycline inducible H2B-mTurquoise2 for live cell imaging2021 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Christiaan H. Arendzen, Steve J. Cramer, Christian M.A.H. Freund, Christine L. Mummery, Adrian Ranga, Olivier Pourquié, +1 more
1citations -
Gene Supplementation of MYO7A or activation of Myo7b for treatment of Usher syndrome 1B2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
David Manuel Mittas, Dina Yehia Otify, Zoran Gavrilov, Thomas Heigl, Jan Suchomski, Paulina Deltuvaite, +27 more
0citations -
Distinct roles of IDR and CCD domains control PABPN1 aggregation and enable therapeutic rescue2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Milad Shademan, Iolanda Vendrell, Alberto Malerba, s Khoshbash, Sarah Flannery, March, +4 more
0citations -
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype2023 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christiaan H. Arendzen, +4 more
46citations