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Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory2024 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Bastian Nießing, Yannik Breitkreuz, Andreas Elanzew, Marcelo A. S. Toledo, P. Vajs, M. Nolden, +9 more
8citations -
Restoration of T and B Cell Differentiation after RAG1 Gene Transfer in Human RAG1 Defective Hematopoietic Stem Cells2024 Biomedicines article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Nataël Sorel, Francisco Díaz-Pascual, Boris Bessot, Hanem Sadek, Chloé Mollet, Myriam Chouteau, +12 more
5citations -
Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads2022 Stem Cell Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Albert Blanch-Asensio, Babet van der Vaart, Mariana Vinagre, Eline Groen, Christiaan H. Arendzen, Christian M.A.H. Freund, +3 more
20citations -
Generation and Culture of Cardiac Microtissues in a Microfluidic Chip with a Reversible Open Top Enables Electrical Pacing, Dynamic Drug Dosing and Endothelial Cell Co‐Culture2022 Advanced Materials Technologies article Engineering 3D Printing in Biomedical Research Open access
Aisen Vivas, Camilo IJspeert, Jesper Yue Pan, Kim Vermeul, Albert van den Berg, Robert C. J. J. Passier, +2 more
30citations -
Enablers and barriers for using reusable trocars: a qualitative study of surgeons’ and residents’ perspectives2026 Surgical Endoscopy article Immunology and Microbiology Medical Device Sterilization and Disinfection Open access
Myrthe M.M. Eussen, Merijn de Kort, Carys Batcup, Merel Kimman, Brigitte A.B. Essers, Frenk van Harreveld, +2 more
0citations -
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs2024 Immunology Letters article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Giorgio Gilioli, Arjan C. Lankester, Sander de Kivit, Frank J. T. Staal, Lisa M. Ott de Bruin
8citations -
Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction2022 Scientific Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Vera Zywitza, Ejona Rusha, Dmitry Shaposhnikov, Jorge Ruiz‐Orera, Narasimha Swamy Telugu, Valentyna M. Rishko, +16 more
28citations -
Generation and genetic repair of two human induced pluripotent cell lines from patients with Epidermolysis Bullosa simplex and dilated cardiomyopathy associated with a heterozygous mutation in the translation initiation codon of KLHL242021 Stem Cell Research article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Veronika Ramovš, Ignacia Fuentes, Christian M.A.H. Freund, Harald M. M. Mikkers, Christine L. Mummery, Karine Raymond
14citations -
CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage2026 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Xiaole Tong, Marieke Visscher, Frank M. Riemers, Daniëlle Versluis, Niels Geijsen, Peng Shang, +2 more
0citations -
Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids2020 Cell Systems article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Jeremy J. Velazquez, Ryan LeGraw, Farzaneh Moghadam, Yuqi Tan, Jacquelyn A. Kilbourne, Joseph C. Maggiore, +8 more
110citations -
Haplotype Motif-Based Models for KIR-Genotype Informed Selection of Hematopoietic Cell Donors Fail to Predict Outcome of Patients With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia
Johannes Schetelig, Henning Baldauf, Linda Köster, Michelle Kuxhausen, Falk Heidenreich, Liesbeth C. de Wreede, +16 more
25citations -
A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues2022 Journal of Personalized Medicine article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Marcelo C. Ribeiro, José M. Rivera‐Arbeláez, Carla Cofiño‐Fabrés, Verena Schwach, Rolf H. Slaats, Simone A. ten Den, +6 more
21citations -
Generation of isogenic allelic series of LMNA-mutated hiPSC lines using the novel and highly-efficient targeting platform, STRAIGHT-IN2024 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Viviana Meraviglia, Albert Blanch-Asensio, Richard P. Davis, Christine L. Mummery, Milena Bellin
0citations