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LncRNA LITATS1 suppresses TGF‐β‐induced EMT and cancer cell plasticity by potentiating TβRI degradation2023 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Chuannan Fan, Qian Wang, Thomas B. Kuipers, Davy Cats, Prasanna Vasudevan Iyengar, Sophie C. Hagenaars, +5 more
69citations -
Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype2020 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Katarina Madunić, Tao Zhang, Oleg A. Mayboroda, Stephanie Holst, Kathrin Stavenhagen, Chunsheng Jin, +3 more
67citations -
IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants2020 Journal of Allergy and Clinical Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Yannic C. Bartsch, Simon Eschweiler, Alexei Leliavski, Hanna B. Lunding, Sander Wagt, Janina Petry, +32 more
67citations -
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling2020 Circulation Research article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Urszula Rykaczewska, Bianca E Suur, Samuel Röhl, Anton Razuvaev, Mariette Lengquist, Maria Sabater‐Lleal, +23 more
66citations -
Dendritic cell vaccination and CD40-agonist combination therapy licenses T cell-dependent antitumor immunity in a pancreatic carcinoma murine model2020 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Sai Ping Lau, Nadine van Montfoort, Priscilla Kinderman, Melanie M. Lukkes, Larissa Klaase, Menno van Nimwegen, +15 more
65citations -
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome2021 Circulation article Biochemistry, Genetics and Molecular Biology Congenital heart defects research Open access
Markus Krane, Martina Dreßen, Gianluca Santamaria, Ilaria My, Christine M. Schneider, Tatjana Dorn, +40 more
65citations -
Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish
Jôsimar Dornelas Moreira, Bjørn E. V. Koch, Suzanne van Veen, Kimberley V. Walburg, Frank Vrieling, Tânia Mara Pinto Dabés Guimarães, +5 more
64citations -
MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells2024 Journal of Clinical Investigation article Immunology and Microbiology Immune responses and vaccinations Open access
Rutger Jan Röring, Priya A. Debisarun, Javier Botey-Bataller, Tsz Kin Suen, Ozlem Pinar Bulut, Gizem Kılıç, +19 more
64citations -
Phylotranscriptomic evidence for pervasive ancient hybridization among Old World salamanders2020 Molecular Phylogenetics and Evolution article Biochemistry, Genetics and Molecular Biology Genomics and Phylogenetic Studies Open access
Loïs Rancilhac, Iker Irisarri, Claudio Angelini, Jan W. Arntzen, Wiesław Babik, Franky Bossuyt, +11 more
61citations -
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce B. J. van Meurs, +6 more
61citations -
Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies2020 Frontiers in Oncology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 2 patents
Natasja L. De Vries, Ahmed Essam Mahfouz, Frits Koning, Noel F.C.C. de Miranda
60citations -
NKG2A is a late immune checkpoint on CD8 T cells and marks repeated stimulation and cell division2021 International Journal of Cancer article Immunology and Microbiology Immune Cell Function and Interaction Open access cited by 2 patents
Linda Borst, Marjolein Sluijter, Gregor Sturm, Pornpimol Charoentong, Saskia J A M Santegoets, Mandy van Gulijk, +8 more
58citations -
Spatial transcriptomics reveal markers of histopathological changes in Duchenne muscular dystrophy mouse models2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Laura G.M. Heezen, Tamim Abdelaal, Maaike van Putten, Annemieke M Aartsma-Rus, Ahmed Essam Mahfouz, Pietro Spitali
55citations -
Lifespan prolonging mechanisms and insulin upregulation without fat accumulation in long-lived reproductives of a higher termite2022 Communications Biology article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Sarah Séité, Mark C. Harrison, David Sillam‐Dussès, Roland Lupoli, Tom J. M. Van Dooren, Alain Robert, +10 more
54citations -
Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies2023 Osteoarthritis and Cartilage article Medicine Osteoarthritis Treatment and Mechanisms Open access
Muhammad Farooq Rai, Kelsey H. Collins, Annemarie Lang, Tristan Maerz, Jeroen Geurts, Cristina Ruíz‐Romero, +9 more
54citations