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Acute cigarette smoke exposure leads to higher viral infection in human bronchial epithelial cultures by altering interferon, glycolysis and GDF15-related pathways2023 Respiratory Research article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Ying Wang, Dennis K. Ninaber, Alen Faiz, Abraham C. van der Linden, Annemarie M. van Schadewijk, René Lutter, +3 more
13citations -
Chemogenetic ubiquitin E1 inhibitor TAK-243 CRISPR screen uncovers HAPSTR1/HUWE1 axis in chromatin proteostasis and cell cycle control2026 Science Advances article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Nila K. van Overbeek, Linda Clijsters, Martina Wirth, Ilona J. de Graaf, Klaas de Lint, Sidrit Uruci, +12 more
0citations -
STING loss attenuates ISG expression without affecting PARP inhibitor sensitivity in Brca1+/− Jak2V617F MPN2026 Scientific Reports article Immunology and Microbiology interferon and immune responses Open access
Mirjam Hanako Sarholz, María Jimena Rodriguez, Tomasz Skórski, Steffen Koschmieder, Julian Baumeister
0citations -
Glucose transport dependency defines a therapeutic vulnerability in JAK2V617F-driven myeloproliferative neoplasms2026 Cell Communication and Signaling article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Patrick Weiand, Nicolas Chatain, Marcelo A. S. Toledo, Julia Moellmann, Tabea Pirker, Siddharth Gupta, +7 more
0citations -
RNA transcripts regulate G-quadruplex landscapes through G-loop formation2025 Science article Biochemistry, Genetics and Molecular Biology DNA and Nucleic Acid Chemistry Open access
Koichi Sato, Jing Lyu, Jeroen van den Berg, Victoria M. Cruz, Joost Schimmel, Clara Esteban-Jurado, +7 more
36citations -
The translocated virulence protein VirD5 causes DNA damage and mutation during Agrobacterium -mediated transformation of yeast2022 Science Advances article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Xiaorong Zhang, Marjolein J. G. Hooykaas, Gerard Paul H. van Heusden, Paul J. J. Hooykaas
8citations -
Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators2024 Molecular & Cellular Proteomics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Rathan S Jadav, Florian Weiland, Sylvie M. Noordermeer, Thomas D. Carroll, Yuandi Gao, Jianming Wang, +11 more
8citations -
HNF1B integrates signals in a feed-forward loop driving kidney disease progression2026 Science article Biochemistry, Genetics and Molecular Biology Renal and related cancers Open access
Pierre Isnard, Munevver Parla Makinistoglu, Michel Leibovici, Jonathan L. Levinsohn, Camille Cohen, Serge Garbay, +11 more
4citations -
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation2021 Nature Cell Biology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent
Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, Yuka Nakazawa, Tycho E.T. Mevissen, Janne J. M. van Schie, +17 more
115citations -
Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis2020 Journal of Hepatology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Antje Mohs, Tobias Otto, Kai Markus Schneider, Mona Peltzer, Mark V. Boekschoten, Christian H. Holland, +7 more
142citations -
Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action2020 Archives of Toxicology article Chemistry Advanced Proteomics Techniques and Applications Open access
Bharath K. Sampadi, Alex Pines, Stephanie Munk, Branislav Mišovic, Anton J.L. de Groot, Bob van de Water, +3 more
17citations -
Mitochondrial Damage and Epithelial-Mesenchymal Transition as Major Triggers of the Development of Idiopathic Pulmonary Fibrosis2024 Fibrosis article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Xiaoshu Guo, Yue Zhang, Yingjie Wang, Xin Pan, Cong Xia, Zhongzheng Li, +3 more
0citations -
Successive cultivation under drought selects for specific microbiome members in the wheat rhizosphere2026 FEMS Microbiology Ecology article Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Adele Pioppi, Sofia I. F. Gomes, Mette Haubjerg Nicolaisen, Xinming Xu, Ákos T. Kovács
0citations -
Replicating a randomized trial with video-feedback to promote positive parenting in parents of school-aged twins.2022 Journal of Family Psychology article Psychology Child and Adolescent Psychosocial and Emotional Development Open access
Jana Runze, Marinus H. van IJzendoorn, Claudia I. Vrijhof, Marian J. Bakermans‐Kranenburg
10citations -
Urinary Amine and Organic Acid Metabolites Evaluated as Markers for Childhood Aggression: The ACTION Biomarker Study2020 Frontiers in Psychiatry article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Fiona A. Hagenbeek, Peter J. Roetman, René Pool, Cornelis Kluft, Amy C. Harms, Jenny van Dongen, +13 more
35citations