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First clinical and myopathological description of a myofibrillar myopathy with congenital onset and homozygous mutation in FLNC2020 Human Mutation article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Heike Kölbel, Andreas Roos, Peter F. M. van der Ven, Teresinha Evangelista, Kay Wilhelm Nolte, Katherine Johnson, +9 more
18citations -
Degradomics-Based Analysis of Tetanus Toxoids as a Quality Control Assay2020 Vaccines article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Thomas J. M. Michiels, Wichard Tilstra, Martin Hamzink, Justin W. de Ridder, Maarten Danial, Hugo D. Meiring, +3 more
8citations -
Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase2022 Biochemical Journal article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Zhuoyao Chen, Jinwei Zhang, Adrián Rafael Murillo‐de‐Ozores, María Castañeda‐Bueno, Francesca D’Amico, Raphael Heilig, +8 more
4citations -
Revealing charge heterogeneity of stressed trastuzumab at the subunit level2023 Analytical and Bioanalytical Chemistry article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Baubek Spanov, Bas Baartmans, Oladapo Olaleye, Simone Nicolardi, Natalia I. Govorukhina, Manfred Wuhrer, +2 more
3citations -
OC 57.1 Peptidomics Reveals Expected and Unexpected Proteolytic Events in Plasma Upon Activation of the Coagulation Cascade2023 Research and Practice in Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Jessica Del Castillo Alferez, Floris P. J. van Alphen, Carmen van der Zwaan, Marleen G. Zuurveld, Kamran Bakhtiari, Arie Johan Hoogendijk, +3 more
0citations -
PredLyP: A computational tool for predicting tissue-specific (phago-)lysosomal post-digestion peptides2025 Computational and Structural Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access
Mattijn Wagt, Cristina Teodósio, Anniek L. de Jager, Jacques J. M. van Dongen, Marcel J. T. Reinders, Paula Díez, +1 more
0citations -
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1–associated membranous nephropathy2020 Journal of Clinical Investigation article Medicine Renal Diseases and Glomerulopathies Open access cited by 2 patents
George Haddad, Johan M. Lorenzen, Hong Ma, Noortje de Haan, Harald Seeger, Christelle Zaghrini, +11 more
180citations -
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra2021 BMC Biology article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, +9 more
27citations -
Aro-Aat Reduces Z-AAT Protein in Pizz Patients and Leads to Improvements in Clinically Relevant Liver Biomarkers2021 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Pavel Strnad, Mattias Mandorfer, Gourab Choudhury, WJ Griffiths, Alice Margaret Turner, Christian Trautwein, +5 more
2citations -
Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes2023 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access cited by 3 patents
Ingo Volker Hartung, Joachim Rudolph, Mary M. Mader, Monique P. C. Mulder, Paul Workman
100citations -
Developing an SI-traceable Lp(a) reference measurement system: a pilgrimage to selective and accurate apo(a) quantification2023 Critical Reviews in Clinical Laboratory Sciences review Medicine Lipoproteins and Cardiovascular Health Open access
Nina M. Diederiks, Yuri E. M. van der Burgt, L. Renee Ruhaak, Christa M. Cobbaert
44citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Miriam Kretschmer, Iryna Ivanova, +15 more
22citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland E. Smith, +13 more
17citations -
Interactions between the Parasite Philasterides dicentrarchi and the Immune System of the Turbot Scophthalmus maximus. A Transcriptomic Analysis2020 Biology article Immunology and Microbiology Aquaculture disease management and microbiota Open access
A. Valle, José Manuel Leiro, Patricia Pereiro, Antonio J. Figueras, Beatriz Novoa, Ron P. Dirks, +1 more
17citations -
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner2020 International Journal of Molecular Sciences article Immunology and Microbiology Phagocytosis and Immune Regulation Open access
Anke Seifert, Justyna Wozniak, Stefan Düsterhöft, Petr Kašpárek, Radislav Sedláček, Stephan Dreschers, +3 more
13citations -
Improved N- and C-Terminal Sequencing of Proteins by Combining Positive and Negative Ion MALDI In-Source Decay Mass Spectrometry2020 Analytical Chemistry article Chemistry Mass Spectrometry Techniques and Applications Open access
Simone Nicolardi, David P. A. Kilgour, Yuri E. M. van der Burgt, Manfred Wuhrer
12citations -
Engineering brain-penetrant PROTACs: Bridging molecular design and CNS delivery2026 Advanced Drug Delivery Reviews review Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Xinuo Li, Jinran Li, Yuan Sun, Tingting Yao, Sai Liu, Haotian Li, +16 more
7citations