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A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features0citations
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Pilot study: transduction of primary paraganglioma chromaffin tumour cells with inducible c-MYC drives cell proliferation2026 Experimental and Clinical Endocrinology & Diabetes article Medicine Adrenal and Paraganglionic Tumors Open access
Juan Zhang, Heggert G Rebel, Dominique Duesman, Charlotte J. Dommering, Abbey Schepers, Peter Devilee, +1 more
0citations -
Deciphering the signaling network of breast cancer improves drug sensitivity prediction2021 Cell Systems article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Marco Tognetti, Attila Gábor, Mi Yang, Valentina Cappelletti, Jonas Windhager, Oscar M. Rueda, +9 more
45citations -
Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody2022 International Journal of Molecular Sciences article Immunology and Microbiology T-cell and B-cell Immunology Open access
Marit J van Elsas, Johan M. S. van der Schoot, Alexander Bartels, Kas Steuten, Duco van Dalen, Zacharias Wijfjes, +5 more
5citations -
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing2024 Pharmacological Research article Medicine Hepatocellular Carcinoma Treatment and Prognosis Open access
Karina Benderski, Paul M. Schneider, Panayiotis Kordeves, Michael Fichter, Jenny Schunke, Federica De Lorenzi, +11 more
4citations -
A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma2021 European Journal of Cancer article Medicine Bladder and Urothelial Cancer Treatments Open access cited by 4 patents
Victor M. Baart, Geertje van der Horst, Marion M. Deken, Shadhvi S. Bhairosingh, Timo Schomann, Vincent Q. Sier, +10 more
16citations -
Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants2025 GeroScience article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Maarouf Baghdadi, Helena M. Hinterding, Thies Gehrmann, Pasquale C. Putter, Mara Neuerburg, Nico Lakenberg, +4 more
2citations -
Additional file 1 of Epigenetic priming of mammalian embryonic enhancer elements coordinates developmental gene networks2025 Figshare article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Christopher D Todd, Jannat Ijaz, Fereshteh Torabi, Oleksandr Dovgusha, Olivia Cracknell, Tim Lohoff, +10 more
0citations -
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations2024 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Ivan Kuzmin, Marilin Moor, Núria Muñoz-Subirana, +7 more
18citations -
Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease2022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman David Bülow, Tiffany Migeon, Sandrine Placier, +3 more
9citations -
Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family2025 Nature Communications article Medicine Clostridium difficile and Clostridium perfringens research Open access
Elma Mons, Jannie G. E. Henderickx, Ingrid M. J. G. Sanders, Anusca G. Rader, Caroline E. Perkins, Florence M. Stel, +4 more
3citations -
EXTH-55. ALL-IN-ONE GENETIC CONSTRUCT TO KNOCKDOWN MIR-21 REDUCES GLIOMA PROLIFERATION IN VITRO2023 Neuro-Oncology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lisa Nieland, Anne B. Vrijmoet, Alexandra J E M de Reus, Benjamin Kleinsteiver, Marike L. D. Broekman, Xandra O. Breakefield, +1 more
1citations -
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro2022 Frontiers in Genetics article Medicine Cutaneous lymphoproliferative disorders research Open access
Eliza Mari Kwesi‐Maliepaard, Muddassir Malik, Tibor van Welsem, Remco van Doorn, Maarten H. Vermeer, Hanneke Vlaming, +2 more
3citations -
GRHL2 Regulation of Growth/Motility Balance in Luminal versus Basal Breast Cancer2023 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access
Zi Wang, Bircan Coban, Chen‐Yi Liao, Qiuyu Liu, Erik H.J. Danen
10citations -
Transformation of primary murine peritoneal mast cells by constitutive KIT activation is accompanied by loss of Cdkn2a/Arf expression2023 Frontiers in Immunology article Immunology and Microbiology Mast cells and histamine Open access
Sandro Capellmann, Herdit M. Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, +4 more
6citations -
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington’s Disease Pathology2022 Journal of Medicinal Chemistry article Neuroscience Genetic Neurodegenerative Diseases Open access
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca E. Jarvis, Wesley Blackaby, Ovadia Lazari, +19 more
34citations -
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation2023 Cellular and Molecular Gastroenterology and Hepatology article Medicine Liver physiology and pathology Open access
Sai Wang, Frederik Link, Mei Han, Roohi Chaudhary, Anastasia Asimakopoulos, Roman Liebe, +12 more
27citations