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Activity-Based Protein Profiling for the Identification of Novel Carbohydrate-Active Enzymes Involved in Xylan Degradation in the Hyperthermophilic Euryarchaeon Thermococcus sp. Strain 2319x1E2022 Frontiers in Microbiology article Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization Open access
Thomas Klaus, Sabrina Ninck, Andreas Albersmeier, Tobias Busche, Daniel Wibberg, Jianbing Jiang, +9 more
16citations -
Activity-Based Protein Profiling of Retaining α-Amylases in Complex Biological Samples2021 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access cited by 3 patents
Yurong Chen, Zachary Armstrong, Marta Artola, Bogdan I. Florea, C.J. Kuo, Casper de Boer, +7 more
31citations -
Manno- epi -cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors2020 Journal of the American Chemical Society article Chemistry Carbohydrate Chemistry and Synthesis Open access
Zachary Armstrong, C.J. Kuo, D. Lahav, Rachel D. Johnson, Thomas J. M. Beenakker, Casper de Boer, +14 more
47citations -
Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases2021 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Sybrin P. Schröder, Wendy A. Offen, Alexandra Males, Yi Jin, Casper de Boer, Jacopo Enotarpi, +6 more
5citations -
Previously Published Phosphatase Probes have Limited Utility Due to their Unspecific Reactivity2024 ChemBioChem article Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access
Franciscus H. G. Ter Brake, Suzanne van Luttikhuizen, Tom van der Wel, Berend Gagestein, Bogdan I. Florea, Mario van der Stelt, +1 more
6citations -
Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate2022 Gut Microbes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Marissa M. Bivins, Natalie K. Barker, +9 more
43citations -
Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate2022 medRxiv preprint Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina Borlandelli, Natalie K. Barker, Alicia A. Sorgen, +8 more
6citations -
Spatially resolved mapping of monoacylglycerol lipase activity in the brain2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cannabis and Cannabinoid Research Open access
Daan van der Vliet, Alex X.Y. Klinkenberg, Rik Platte, Kieran P. Higgins, Susanne Prokop, Mirjam C. W. Huizenga, +8 more
0citations -
Huib32: A Potent and Selective USP32 Inhibitor Modulating Endosomal Processes and Advancing Cell-Permeable USP32 Probes2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Stephan Scherpe, Vito Pol, Raymond Kooij, Adán Pinto-Fernández, Rayman T.N. Tjokrodirijo, Darragh Patrick O'Brien, +6 more
1citations -
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Yuqing Jia, Merve Oyken, Robbert Q. Kim, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Antonius P. A. Janssen, +4 more
7citations -
Immunoproteasome Activity in Chronic Lymphocytic Leukemia as a Target of the Immunoproteasome-Selective Inhibitors2022 Cells article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access cited by 3 patents
Andrej Bešše, Marianne Kraus, Max Alberto Mendez-Lopez, Elmer Maurits, Herman S. Overkleeft, Christoph Driessen, +1 more
4citations -
An Environment-Sensitive Turn-On Fluorescent Probe Enables Detection of PAD4 Activation in Response to Distinct NETosis Stimuli2026 ACS Chemical Biology article Immunology and Microbiology Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Enebie Ramos Cáceres, Moniek M. Bioch, Mike L.W.J. Smeenk, Rocaya C. Groß, Kimberly M. Bonger
2citations -
Synthesis and Biological Evaluation of Deoxycyclophellitols as Human Retaining β‐Glucosidase Inhibitors2024 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Yevhenii Radchenko, Qin Su, Sybrin P. Schröder, Luke van Gijlswijk, Marta Artola, Johannes M. F. G. Aerts, +2 more
3citations -
Conformational and Electronic Variations in 1,2‐ and 1,5a‐Cyclophellitols and their Impact on Retaining α‐Glucosidase Inhibition2024 Chemistry - A European Journal article Chemistry Carbohydrate Chemistry and Synthesis Open access
Tim P. Ofman, Jurriaan J. A. Heming, Alba Nin‐Hill, Florian Küllmer, E. J. MORAN, Roy Steneker, +11 more
4citations -
Oseltamivir aziridines are potent influenza neuraminidase inhibitors and imaging agents2026 Proceedings of the National Academy of Sciences article Medicine Influenza Virus Research Studies Open access
Merijn B. L. Vriends, E. J. MORAN, Martín Calvelo, Thomas Ross Hansen, Isabelle B. Pickles, Xincheng Xin, +17 more
2citations -
Functional Differentiation of GH172 Arabinofuranosidases Through Divergent Quaternary Structures2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Materials Science Enzyme Structure and Function Open access
Jennifer Ross, Moescha Hoopman, Florian Küllmer, Omar Al-Jourani, Augustinas Silale, Morwan M. Osman, +17 more
0citations -
Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools2025 ChemBioChem article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Francesca D’Amico, Cami M. P. Talavera Ormeño, Shivanganie Poeran, Jimmy J.L.L. Akkermans, Rayman T.N. Tjokrodirijo, Bharath K. Sampadi, +3 more
3citations -
A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes2025 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Charlotte Wijne, Francesca D’Amico, David A. Pérez Berrocal, Monique P. C. Mulder, Hidde L. Ploegh
1citations