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An integrated multimodal pan-organ atlas of the female reproductive system across the lifespan contextualises gynaecological pathologies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Celeste E Cohen, Antonio Párraga-Leo, Leticia Rodríguez-Montes, Christina E. Kim, Marie Moullet, Ana Paredes, +49 more
0citations -
962 Single-cell spatial in situ transcriptomics unravels vulvar HSIL composition associated with complete response to therapeutic vaccination2023 Regular and Young Investigator Award Abstracts conference-abstract Medicine Cervical Cancer and HPV Research Open access
Ziena Abdulrahman, Mariëtte I.E. van Poelgeest, Marij J.P. Welters, Sjoerd van der Burg
0citations -
794 CD163+ macrophages are an effective target for antitumor therapy2025 Journal for ImmunoTherapy of Cancer conference-abstract Immunology and Microbiology Immune cells in cancer Open access
Pieter J. Schol, Maarten K. Nijen Twilhaar, Camilla Labrie, Roderick C. Slieker, Jonas Heilskov Graversen, Anders Etzerodt, +2 more
0citations -
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches2022 Cell article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 4 patents
Martin Guilliams, Johnny Bonnardel, Birthe Haest, Bart Vanderborght, Camille Wagner, Anneleen Remmerie, +31 more
1,021citations -
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses2021 Molecular Systems Biology article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Aurélien J. F. Dugourd, Christoph Kuppe, Marco Sciacovelli, Enio Gjerga, Attila Gábor, Kristina Bennet Emdal, +12 more
156citations -
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer’s disease2022 Communications Biology article Biochemistry, Genetics and Molecular Biology Sphingolipid Metabolism and Signaling Open access cited by 1 patent
Priyanka Baloni, Matthias Arnold, Luna Buitrago, Kwangsik T. Nho, Herman Moreno, Kevin Huynh, +47 more
114citations -
Spatial transcriptomic characterization of pathologic niches in IPF2024 Science Advances article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access cited by 1 patent
Christoph H. Mayr, Diana Santacruz, Sebastian Jarosch, Marina Bleck, Angela McNabola, Charlotte Lempp, +11 more
106citations -
Spatial multi-omic map of human myocardial infarction2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Christoph Kuppe, Ricardo O. Ramirez Flores, Zhijian Li, Monica Toft Hannani, Jovan Tanevski, Maurice Halder, +13 more
78citations -
Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis2021 European Heart Journal Open article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Lotte Slenders, Lennart P. L. Landsmeer, Kai Cui, Marie A.C. Depuydt, Maarten C. Verwer, Joost M. Mekke, +17 more
77citations -
Consensus Transcriptional Landscape of Human End‐Stage Heart Failure2021 Journal of the American Heart Association article Medicine Cardiac Fibrosis and Remodeling Open access
Ricardo O. Ramirez Flores, Jan D. Lanzer, Christian H. Holland, Florian Leuschner, Patrick Most, Jobst‐Hendrik Schultz, +2 more
73citations -
Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Meltem Weger, Daniel Alpern, Antoine Cherix, Sriparna Ghosal, Jocelyn Grosse, Julie Russeil, +4 more
71citations -
Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression2022 Genome biology article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 1 patent
Thomas H. Jonkman, Koen F. Dekkers, Roderick C. Slieker, Crystal D. Grant, M. Arfan Ikram, Marleen M. J. van Greevenbroek, +5 more
71citations -
CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors2024 Cellular and Molecular Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Xin Lei, Daniël de Groot, Marij J.P. Welters, Tom de Wit, Ellen Schrama, Hans van Eenennaam, +10 more
65citations -
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity2020 Nature Communications article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access
J. G. Coen van Hasselt, Rayees Rahman, Jens Hansen, Alan D. Stern, Jaehee V. Shim, Yuguang Xiong, +10 more
52citations -
Advances and challenges in cell–cell communication inference: a comprehensive review of tools, resources, and future directions2025 Briefings in Bioinformatics review Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Giulia Cesaro, James Shiniti Nagai, Gnoato Nicolò, Alice Chiodi, Gaia Tussardi, Vanessa Klöker, +6 more
48citations -
Phosphate starvation causes different stress responses in the lipid metabolism of tomato leaves and roots2020 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids article Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access
Julia Pfaff, Alisandra K. Denton, Björn Usadel, Christian Pfaff
45citations -
IL-33 Expression Is Lower in Current Smokers at both Transcriptomic and Protein Levels2023 American Journal of Respiratory and Critical Care Medicine article Immunology and Microbiology IL-33, ST2, and ILC Pathways Open access
Alen Faiz, Rashad Mohammad Mahbub, Fia Sabrina Boedijono, Milan I. Tomassen, Wierd Kooistra, Wim Timens, +25 more
43citations