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A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers2023 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access cited by 2 patents
Daipeng Chen, Zary Forghany, Xinxin Liu, Haijiang Wang, Roeland M. H. Merks, David A. Baker
20citations -
Design, Synthesis, and In Silico Multitarget Pharmacological Simulations of Acid Bioisosteres with a Validated In Vivo Antihyperglycemic Effect
Elix Alberto Domínguez-Mendoza, Yelzyn Galván-Ciprés, Josué Martínez‐Miranda, Cristian Miranda-González, Blanca Colín-Lozano, Emanuel Hernández‐Núñez, +3 more
17citations -
Mutational heterogeneity of imatinib resistance and efficacy of ripretinib vs sunitinib in patients with gastrointestinal stromal tumor: ctDNA analysis from INTRIGUE.2023 Journal of Clinical Oncology conference-abstract Medicine Gastrointestinal Tumor Research and Treatment
Sebastian Bauer, Robin L. Jones, Suzanne George, Hans A. J. Gelderblom, Patrick Schöffski, Margaret von Mehren, +13 more
16citations -
Parp7 generates an ADP-ribosyl degron that controls negative feedback of androgen signaling2025 The EMBO Journal article Biochemistry, Genetics and Molecular Biology Prostate Cancer Treatment and Research Open access
Krzysztof Wierbiłowicz, Chunsong Yang, Ahmed Almaghasilah, Patryk Adam Wesołowski, Philipp Pracht, Natalia M. Dworak, +7 more
15citations -
Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication2023 Phytomedicine article Pharmacology, Toxicology and Pharmaceutics Hops Chemistry and Applications Open access
Anna-Maria Herzog, Katharina Göbel, Luigi Marongiu, Natalia Ruétalo, Marta Campos Alonso, Christian Leischner, +8 more
14citations -
Novel selective glucocorticoid receptor modulator GRM-01 demonstrates dissociation of anti-inflammatory effects from adverse effects on glucose and bone metabolism2025 Frontiers in Pharmacology article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Florian Jakob, Stephanie Hennen, Michael Gautrois, Feras Khalil
13citations -
Mitigating Drug–Target–Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors2023 Clinical Pharmacology & Therapeutics article Immunology and Microbiology Complement system in diseases Open access
Jun‐ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean‐Eric Charoin, +23 more
10citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 Human Molecular Genetics article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Lodewijk J.A. Toonen, +5 more
8citations -
Probing the electronic structure and ground state symmetry of gas phase C60+ via VUV photoionization and comparison with theory2024 The Journal of Chemical Physics article Chemistry Fullerene Chemistry and Applications Open access
Helgi Rafn Hróðmarsson, Mathias Rapacioli, Fernand Spiegelman, Gustavo A. García, Jordy Bouwman, Laurent Nahon, +1 more
5citations -
An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial
Jun‐ichi Nishimura, Antoine Soubret, Simon Buatois, Jean‐Eric Charoin, Sasha Sreckovic, Christoph Marcus Bucher, +21 more
3citations -
Towards the design of artificial sensing materials via quantum-informed explainable AI2026 Journal of Cheminformatics article Materials Science Machine Learning in Materials Science Open access
Li Chen, Leonardo Rafael Medrano Sandonas, Shirong Huang, Alexander Croy, Gianaurelio Cuniberti
2citations -
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Elsa C. Kuijper, Linda M. van der Graaf, Barry A. Pepers, Mariana Guimarães Ramos, Sylvia Korhorn, Davy Cats, +4 more
1citations -
Deciphering conformational selectivity in the A 2A adenosine G protein-coupled receptor by Free Energy simulations2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Willem Jespers, Laura H. Heitman, Adriaan P. IJzerman, Eddy Sotelo, Gerard J. P. van Westen, Johan Åqvist, +1 more
1citations -
Biocatalytic Potential of a Mycobacterial Aminoacylase for Synthesis of N‐ Acyl‐L‐Amino Acids in Aqueous Media2026 ChemBioChem article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization Open access
Jessika Wirges, Gerrit Haeger, Laureline Gennesseaux, Yann P. Guiavarc’h, Catherine Humeau, Cédric Paris, +6 more
1citations