Papers matching “alternative complement pathway” 52
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Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?2022 Molecular Immunology article Immunology and Microbiology Complement system in diseases Open access
Jeffrey J. Damman, Antien L. Mooyaart, Thierry P. P. van den Bosch, Marc A. Seelen, Martijn B. van Doorn
20citations -
The complement alternative pathway in paroxysmal nocturnal hemoglobinuria: From a pathogenic mechanism to a therapeutic target2022 Immunological Reviews review Immunology and Microbiology Complement system in diseases Open access
Antonio Maria Risitano, Camilla Frieri, Eleonora Urciuoli, Luana Marano
52citations -
Mathematical Modelling of Alternative Pathway of Complement System2020 Bulletin of Mathematical Biology article Immunology and Microbiology Complement system in diseases Open access
Suruchi Bakshi, Fraser Cunningham, Eva-Maria Nichols, Marta Biedzka-Sarek, Jessica Neisen, Sebastien Petit-Frere, +5 more
13citations -
Alternative pathway–mediated tubular complement activation in human proteinuric kidney diseases: a proof-of-concept study2025 Clinical Kidney Journal article Immunology and Microbiology Complement system in diseases Open access
Firas Farisi Alkaff, Rosa G. M. Lammerts, Gesa Tiller, Marius Christianus van den Heuvel, Ingeborg M. Bajema, Mohamed R. Daha, +2 more
5citations -
#3018 Iptacopan's rapid and sustained inhibition of overactive complement alternative pathway in C3G: Exploratory analysis from the Phase 3 APPEAR-C3G study2025 Nephrology Dialysis Transplantation article Immunology and Microbiology Complement system in diseases Open access
Erica Daina, Giuseppe Remuzzi, David Kavanagh, Imelda Schuhmann, Rubeen Israni, Hari Varun Kalluri, +4 more
0citations -
Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Complement system in diseases Open access
Swagata Konwar, Sophie Schroda, Jessika Kleindienst, Eva L. Decker, Martin Pohl, Barbara Zieger, +10 more
0citations -
Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis2025 Journal of Clinical Investigation article Immunology and Microbiology Complement system in diseases Open access
Swagata Konwar, Sophie Schroda, Manuel Rogg, Jessika Kleindienst, Eva L. Decker, Martin Pöhl, +9 more
8citations -
Correction to: Mathematical Modelling of Alternative Pathway of Complement System2021 Bulletin of Mathematical Biology erratum Immunology and Microbiology Complement system in diseases Open access
Suruchi Bakshi, Fraser Cunningham, Eva-Maria Nichols, Marta Biedzka-Sarek, Jessica Neisen, Sebastien Petit-Frere, +5 more
0citations -
Initial properdin binding contributes to alternative pathway activation at the surface of viable and necrotic cells2022 European Journal of Immunology article Immunology and Microbiology Complement system in diseases Open access
Mieke F. van Essen, Nicole Schlagwein, Elisa M.P. van den Hoven, Daniëlle J. van Gijlswijk‐Janssen, Rosalie Lubbers, Ramon M. van den Bos, +4 more
8citations -
Monotherapy Treatment with Zaltenibart (OMS906), an Alternative Pathway Masp-3 Inhibitor, Improved Key Hematologic Parameters in Patients with PNH with a Suboptimal Response to Ravulizumab: Interim Results from a Phase 2 Proof-of-Concept Study
Morag Griffin, Richard J. Kelly, Mathilde Gavillet, Petra Muus, Britta Hoechsmann, W. Jason Cummings, +4 more
4citations -
Brain death-induced lung injury is complement dependent, with a primary role for the classical/lectin pathway2020 American Journal of Transplantation article Immunology and Microbiology Complement system in diseases Open access
Judith E. van Zanden, Neeltina M. Jager, Marc A. Seelen, Mohamed R. Daha, Zwanida J. Veldhuis, Henri G. D. Leuvenink, +1 more
7citations -
Apply-PNH: Analysis of complement pathway biomarkers provides evidence for pharmacodynamic response in PNH patients who receive oral iptacopan monotherapy versus continuing anti-C5 therapy2025 Blood conference-abstract Immunology and Microbiology Complement system in diseases Open access
Régis Peffault de Latour, Richard Kelly, Austin Gladston Kulasekararaj, Alexander Röth, Phillip Scheinberg, Yasutaka Ueda, +4 more
0citations -
Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Jenny Giang, Martijn B. A. van Doorn, Gilles F.H. Diercks, Santiago Rodrı́guez de Córdoba, Thierry P. P. van den Bosch, Marco W.J. Schreurs, +2 more
3citations -
The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?2021 Journal of Clinical Medicine article Immunology and Microbiology Complement system in diseases Open access
Felix Poppelaars, Bernardo Faria, Wilhelm Schwaeble, Mohamed R. Daha
50citations -
Complement Activation is More Pronounced in the Kidneys of Critically Ill Patients With COVID-19 Than in Those With Bacterial Sepsis2025 Kidney International Reports article Immunology and Microbiology Complement system in diseases Open access
Firas Farisi Alkaff, Grietje G Talen, Marius Christianus van den Heuvel, Meint Volbeda, Matijs van Meurs, Jill Moser, +3 more
1citations -
IMAGINATION: A Global Phase 3 Trial of RO7434656, an Antisense Oligonucleotide Inhibitor of Complement Factor B, in IgA Nephropathy2023 Journal of the American Society of Nephrology conference-abstract Medicine Renal Diseases and Glomerulopathies Open access
Jonathan Barratt, Jürgen Floege, Vishal Duggal, Nadine Schmit, Jeannette Lo, Brad H. Rovin
4citations