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Tandem Substitutions in Somatic Hypermutation2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Julieta Sepúlveda-Yáñez, Diego Álvarez-Saravia, Bas Pilzecker, Pauline A. van Schouwenburg, Mirjam van der Burg, Hendrik Veelken, +3 more
4citations -
Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation2023 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Aldo Spanjaard, Maria Stratigopoulou, Daniël de Groot, Muhammad Assad Aslam, Paul C.M. van den Berk, Chantal Stappenbelt, +7 more
2citations -
High microbiota reactivity of adult human intestinal IgA requires somatic mutations2020 The Journal of Experimental Medicine article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Johanna Kabbert, Julia Benckert, Tim Rollenske, Thomas C. A. Hitch, Thomas Clavel, Vuk Cerovic, +2 more
91citations -
Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load2021 Arthritis Research & Therapy article Medicine Rheumatoid Arthritis Research and Therapies Open access
Sanne Reijm, Theresa Kissel, Gerrie Stoeken‐Rijsbergen, Linda M. Slot, Corrie M. Wortel, Hugo J. van Dooren, +11 more
23citations -
Causative mechanisms and clinical impact of immunoglobulin deficiencies in ataxia telangiectasia2024 Journal of Allergy and Clinical Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Sanami Takada, Thomas J. Weitering, Nienke J.H. van Os, Likun Du, Ingrid Pico‐Knijnenburg, Thomas B. Kuipers, +6 more
18citations -
B-cell immunodeficiency associated with polynucleotide kinase 3′-phosphatase (PNKP) deficiency2025 Journal of Allergy and Clinical Immunology Global article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Sanami Takada, Tsubasa Okano, Kay Tanita, Kaima Tsukada, Masato Watanabe, Atsushi Hijikata, +14 more
0citations -
Integration of Mutational Signature Analysis with 3D Chromatin Data Unveils Differential AID-Related Mutagenesis in Indolent Lymphomas2021 International Journal of Molecular Sciences article Medicine Lymphoma Diagnosis and Treatment Open access
Julieta Sepúlveda-Yáñez, Diego Álvarez-Saravia, José Fernández-Goycoolea, Jacqueline Aldridge, Cornelis A.M. van Bergen, Ward F.M. Posthuma, +3 more
2citations -
Targeting autoreactive B cells in rheumatoid arthritis through MHC class I-presented BCR-derived neo-epitopes2026 Journal of Autoimmunity article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Renee van de Wetering, Arieke S. B. Kampstra, Michel G.D. Kester, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Peter A. van Veelen, +3 more
0citations -
Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation2022 Science Advances article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access
Theresa Kissel, Changrong Ge, Lise Hafkenscheid, Joanneke C. Kwekkeboom, Linda M. Slot, Marco Cavallari, +18 more
77citations -
A Comparison of Immunoglobulin Variable Region N-Linked Glycosylation in Healthy Donors, Autoimmune Disease and Lymphoma2020 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Glycosylation and Glycoproteins Research Open access cited by 1 patent
Esther M. Vletter, Marvyn T. Koning, Hans Ulrich Scherer, Hendrik Veelken, René E. M. Toes
37citations -
Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data2022 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Tommaso Andreani, Linda M. Slot, Samuel Gabillard, Carsten Strübing, Yaligara Veeranagouda, Aleida M. Bakker, +5 more
14citations -
RNA binding proteins control the G 2 -M checkpoint of the germinal center B cell2025 Science Immunology article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access
Fiamma Salerno, Alex J. Whale, Louise S. Matheson, Davide Maria Vespasiani, William S. Foster, Twm J. Mitchell, +8 more
11citations -
Deciphering imprints of impaired memory B-cell maturation in germinal centers of three patients with common variable immunodeficiency2022 Frontiers in Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Pauline A. van Schouwenburg, Susanne Unger, Kathryn J. Payne, Fabian M. P. Kaiser, Ingrid Pico‐Knijnenburg, Jens Pfeiffer, +8 more
11citations -
Improving naive B cell isolation by absence of CD45RB glycosylation and CD27 expression in combination with BCR isotype2022 European Journal of Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Jana Koers, Sabrina Pollastro, Simon Tol, Ilse T. G. Niewold, Pauline A. van Schouwenburg, Niek de Vries, +1 more
4citations -
Plasma cells are not restricted to the CD27+ phenotype: characterization of CD27-CD43+ antibody-secreting cells2023 Frontiers in Immunology article Immunology and Microbiology T-cell and B-cell Immunology Open access
Kris Covens, Bert Verbinnen, Britt G. de Jong, Leen Moens, Greet Wuyts, Geert R. Verheyen, +11 more
4citations -
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL2024 The Journal of Experimental Medicine article Medicine Lymphoma Diagnosis and Treatment Open access
Janneke A. Eken, Marvyn T. Koning, Kristýna Kupcová, Julieta Sepúlveda-Yáñez, Ruben A. L. de Groen, Edwin Quinten, +10 more
19citations -
Dual dynamics of persistence and recruitment characterise the ACPA-expressing B cell response in rheumatoid arthritis2026 Annals of the Rheumatic Diseases article Medicine Rheumatoid Arthritis Research and Therapies Open access
Renee van de Wetering, Shachi Mujumdar, Linda M. Slot, Arieke S. B. Kampstra, Sanne Kroos, Rian Schopmeijer, +5 more
1citations -
Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations2021 Genes and Immunity article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Indu Khatri, Magdalena A. Berkowska, Erik B. van den Akker, Cristina Teodósio, Marcel J. T. Reinders, Jacques J. M. van Dongen
32citations -
Defective formation of IgA memory B cells, Th1 and Th17 cells in symptomatic patients with selective IgA deficiency2020 Clinical & Translational Immunology article Immunology and Microbiology Immunodeficiency and Autoimmune Disorders Open access
Christina Großerichter-Wagener, Alexander Franco‐Gallego, Fatemeh Ahmadi, Marcela Moncada‐Vélez, Virgil A. S. H. Dalm, Jessica Lineth Rojas, +12 more
22citations