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Mapping the glial transcriptome in Huntington’s disease using snRNAseq: selective disruption of glial signatures across brain regions2024 Acta Neuropathologica Communications article Neuroscience Genetic Neurodegenerative Diseases Open access
Sunniva M. K. Bøstrand, Luise A. Seeker, Nadine Bestard-Cuche, Nina-Lydia Kazakou, Sarah Jäkel, Boyd Kenkhuis, +5 more
11citations -
Bronchial Thermoplasty Induced Changes in Blood Transcriptome Profile of Patients with Severe Asthma2026 International Journal of Molecular Sciences article Medicine Asthma and respiratory diseases Open access
Sofi M. Vassileva, Jelle M. Blankestijn, Annika W.M. Goorsenberg, Shahriyar Shahbazi Khamas, Stefania Principe, Mahmoud I. Abdel‐Aziz, +8 more
0citations -
Additional file 1 of Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia2026 Figshare article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lieke Michielsen, Justine Hsu, Anoushka Joglekar, Natan Belchikov, Marcel J. T. Reinders, Hagen Tilgner, +1 more
0citations -
Additional file 1 of Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia2026 Figshare article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lieke Michielsen, Justine Hsu, Anoushka Joglekar, Natan Belchikov, Marcel J. T. Reinders, Hagen Tilgner, +1 more
0citations -
Additional file 2 of Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia2026 Figshare article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lieke Michielsen, Justine Hsu, Anoushka Joglekar, Natan Belchikov, Marcel J. T. Reinders, Hagen Tilgner, +1 more
0citations -
Additional file 2 of Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia2026 Figshare article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lieke Michielsen, Justine Hsu, Anoushka Joglekar, Natan Belchikov, Marcel J. T. Reinders, Hagen Tilgner, +1 more
0citations -
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain2021 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access cited by 1 patent
Anoushka Joglekar, Andrey D. Prjibelski, Ahmed Essam Mahfouz, Paul G. Collier, Susan Lin, Anna Katharina Schlusche, +24 more
233citations -
GeneSurfer enables transcriptome-wide exploration and annotation of gene co-expression modules in 3D spatial transcriptomics data2025 iScience article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Chang Li, Julian Thijssen, Thomas Kroes, Ximaine R. van der Burg, Louise van der Weerd, Thomas Höllt, +1 more
0citations -
Normal hearing function genetics: have you heard all about it? An integrated approach of genome-wide association studies and transcriptome-wide association studies in three Italian cohorts
Aurora Santin, Giulia Pianigiani, Alessandro Gialluisi, Alessandro Pecori, Beatrice Spedicati, Mariarosaria Persichillo, +13 more
2citations -
Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer’s, CADASIL, and Traumatic Brain Injury2026 Nature Communications article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Katrine Dahl Bjørnholm, H. Li, G. Mocci, W. Shao, E. Baldisseri, S. B. Rao, +17 more
0citations -
Reference-based cell type matching of in situ image-based spatial transcriptomics data on primary visual cortex of mouse brain2023 Scientific Reports article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yun Zhang, Jeremy A. Miller, Jeongbin Park, Boudewijn P. F. Lelieveldt, Brian Long, Tamim Abdelaal, +12 more
20citations -
Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation
Jacobus C. Buurstede, Eduardo Henrique de Lima Umeoka, Marcia Santos da Silva, Harm J. Krugers, Marian Joëls, Onno Cornelis Meijer
6citations -
Human cortical spheroids with a high diversity of innately developing brain cell types2023 Stem Cell Research & Therapy article Neuroscience Neurogenesis and neuroplasticity mechanisms Open access
Kim M. A. De Kleijn, Wieteke Ameliek Zuure, Kirsten R. Straasheijm, M. Cristina Avramut, Roman I. Koning, Gerard J.M. Martens
15citations -
Transcriptomic signatures of brain regional vulnerability to Parkinson’s disease2020 Communications Biology article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Arlin Keo, Ahmed Essam Mahfouz, Angela M. T. Ingrassia, Jean‐Pascal Meneboo, Céline Villenet, Eugénie Mutez, +7 more
91citations -
Transcriptional glucocorticoid effects in the brain: Finding the relevant target genes2022 Journal of Neuroendocrinology article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Onno Cornelis Meijer, Jacobus C. Buurstede, Eva M. G. Viho, Jorge Miguel Amaya, Anne-Sophie C A M Koning, Merel van der Meulen, +4 more
31citations -
Brain malformations and seizures by impaired chaperonin function of TRiC2024 Science article Biochemistry, Genetics and Molecular Biology Heat shock proteins research Open access
Florian Kraft, Piere Rodriguez-Aliaga, Kamil K. Zajt, Dimah Hasan, Ting-Ting Lee, Elisabetta Flex, +76 more
28citations -
The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles2024 Molecular Therapy Oncology article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Konstantinos Vazaios, Εftychia Stavrakaki, Lisette B. Vogelezang, Jie Ju, Piotr Waranecki, Dennis Serge Metselaar, +13 more
6citations -
Cingulate networks associated with gray matter loss in Parkinson's disease show high expression of cholinergic genes in the healthy brain2021 European Journal of Neuroscience article Medicine Parkinson's Disease Mechanisms and Treatments Open access
Arlin Keo, Oleh Dzyubachyk, Jeroen van der Grond, Anne Hafkemeijer, Wilma D. J. van de Berg, Jacobus Johannes van Hilten, +2 more
9citations -
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information2020 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Sebastian Guelfi, Karishma D’Sa, Juan Antonio Botía, Jana Vandrovcová, Regina Hertfelder Reynolds, David Zhang, +94 more
39citations