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Estimating individualized treatment effects from randomized controlled trials: a simulation study to compare risk-based approaches2023 BMC Medical Research Methodology article Mathematics Advanced Causal Inference Techniques Open access
Alexandros Rekkas, Peter R. Rijnbeek, David M. Kent, Ewout Willem Steyerberg, David V. Klaveren
14citations -
Risk of bias of prognostic models developed using machine learning: a systematic review in oncology2022 Diagnostic and Prognostic Research review Mathematics Statistical Methods in Epidemiology Open access
Paula Dhiman, Jie Ma, Constanza L. Andaur Navarro, Benjamin Speich, Garrett Scott Bullock, Johanna AAG Damen, +6 more
80citations -
Key Aspects of Prognostic Model Development and Interpretation From a Clinical Perspective2021 JAMA Otolaryngology–Head & Neck Surgery article Mathematics Statistical Methods in Epidemiology
Arta Hoesseini, Nikki van Leeuwen, Aniel Sewnaik, Ewout Willem Steyerberg, Robert J. Baatenburg de Jong, Hester Floor Lingsma, +1 more
40citations -
Methodological Insights on Biomarker‐Based Patient Selection: A Review of Scientific Advice Procedures at the European Medicines Agency2025 Clinical Pharmacology & Therapeutics article Mathematics Statistical Methods in Clinical Trials Open access
Cynthia Huber, Joerg Zinserling, Norbert Benda, Thorsten Vetter, Marcia Viviane Rückbeil
8citations -
Assessing Performance and Clinical Usefulness in Prediction Models With Survival Outcomes: Practical Guidance for Cox Proportional Hazards Models2022 Annals of Internal Medicine article Mathematics Statistical Methods in Epidemiology Open access
David J. McLernon, Daniele Giardiello, Ben Van Calster, Laure Wynants, Nan van Geloven, Maarten van Smeden, +18 more
164citations -
Methodological conduct of prognostic prediction models developed using machine learning in oncology: a systematic review2022 BMC Medical Research Methodology review Mathematics Statistical Methods in Epidemiology Open access
Paula Dhiman, Jie Ma, Constanza L. Andaur Navarro, Benjamin Speich, Garrett Scott Bullock, Johanna AAG Damen, +6 more
138citations -
Predictive approaches to heterogeneous treatment effects: a scoping review2020 BMC Medical Research Methodology article Mathematics Statistical Methods in Clinical Trials Open access
Alexandros Rekkas, Jessica K. Paulus, Gowri Raman, John B. Wong, Ewout Willem Steyerberg, Peter R. Rijnbeek, +2 more
88citations -
Real-world and natural history data for drug evaluation in Duchenne muscular dystrophy: suitability of the North Star Ambulatory Assessment for comparisons with external controls
Francesco Muntoni A, James Signorovitch, Gautam Sajeev, Nathalie Goemans, Brenda L. Y. Wong, Cuixia Tian, +12 more
40citations -
Estimation of required sample size for external validation of risk models for binary outcomes2021 Statistical Methods in Medical Research article Mathematics Statistical Methods in Epidemiology Open access
Menelaos Pavlou, Qu Chen, Rumana Omar, Shaun R. Seaman, Ewout Willem Steyerberg, Ian R. White, +1 more
60citations -
Lessons learnt when accounting for competing events in the external validation of time-to-event prognostic models2021 International Journal of Epidemiology article Mathematics Statistical Methods in Epidemiology Open access
Chava L. Ramspek, Lucy Teece, Kym I E Snell, Marie Evans, Richard D Riley, Maarten van Smeden, +2 more
45citations -
Missing Data in Prediction Research: A Five-Step Approach for Multiple Imputation, Illustrated in the CENTER-TBI Study2021 Journal of Neurotrauma article Mathematics Statistical Methods and Bayesian Inference Open access
Benjamin Yaël Gravesteijn, Charlie Aletta Sewalt, Esmée Venema, Daan Nieboer, Ewout Willem Steyerberg, Cecilia A. I. Åkerlund, +92 more
44citations -
Automated causal inference in application to randomized controlled clinical trials2022 Nature Machine Intelligence article Mathematics Advanced Causal Inference Techniques Open access
Ji Q. Wu, Nanda Horeweg, Marco de Bruyn, Remi A. Nout, Ina Maria Jurgenliemk-Schulz, Ludy C.H.W. Lutgens, +7 more
18citations -
Randomization in the age of platform trials: unexplored challenges and some potential solutions2025 BMC Medical Research Methodology article Mathematics Statistical Methods in Clinical Trials Open access
Olga M. Kuznetsova, Jennifer Ross, Daniel Bodden, Freda Cooner, Jonathan Chipman, Peter Jacko, +7 more
3citations -
Automated causal inference in application to randomized controlled clinical trials2022 arXiv (Cornell University) preprint Mathematics Advanced Causal Inference Techniques Open access
Jiqing Wu, Nanda Horeweg, Marco de Bruyn, Remi A. Nout, Ina Maria Jurgenliemk-Schulz, Ludy C.H.W. Lutgens, +7 more
1citations