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Predicting Mutational Status of Driver and Suppressor Genes Directly from Histopathology With Deep Learning: A Systematic Study Across 23 Solid Tumor Types
Chiara Maria Lavinia Loeffler, Nadine Therese Gaisa, Hannah Sophie Muti, Marko van Treeck, Amelie Echle, Narmin Ghaffari Laleh, +5 more
26citations -
Benchmarking artificial intelligence methods for end-to-end computational pathology2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science AI in cancer detection Open access
Narmin Ghaffari Laleh, Hannah Sophie Muti, Chiara Maria Lavinia Loeffler, Amelie Echle, Oliver Lester Saldanha, Faisal Mahmood, +17 more
15citations -
Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding2025 The Journal of Physical Chemistry B article Computer Science Computational Drug Discovery Methods Open access
Sukrit Singh, Vytautas Gapsys, Matteo Aldeghi, David Schaller, Aziz M. Rangwala, Jessica B. White, +10 more
15citations -
Improving Model Accuracy for Imbalanced Image Classification Tasks by Adding a Final Batch Normalization Layer: An Empirical Study8citations
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Dynamic prediction of mortality in COVID-19 patients in the intensive care unit: A retrospective multi-center cohort study2022 Intelligence-Based Medicine article Computer Science Machine Learning in Healthcare Open access
Jim M Smit, Jesse H. Krijthe, Henrik Endeman, Andrei N. Tintu, Yolanda B. de Rijke, Diederik A M P J Gommers, +37 more
6citations -
Towards an Isabelle Theory for distributed, interactive systems : the untimed case2020 RWTH Publications (RWTH Aachen) report Computer Science Logic, programming, and type systems Open access
Jens Christoph Bürger, Hendrik Kausch, Deni Raco, Jan Oliver Ringert, Bernhard Rumpe⋆, Sebastian Stüber, +1 more
3citations -
Prospective evaluation of structure-based simulations reveal their ability to predict the impact of kinase mutations on inhibitor binding2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Sukrit Singh, Vytautas Gapsys, Matteo Aldeghi, David Schaller, Aziz M. Rangwala, Jessica B. White, +10 more
3citations -
Machine Learning-aided Discovery of Novel Chemotype Antagonists for G Protein-coupled Receptors: The Case of the Adenosine A 2A Receptor2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Jonas Goßen, Rui Pedro Ribeiro, Dirk DB Bier, Bernd Neumaier, Paolo Carloni, Alejandro Giorgetti, +1 more
2citations