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Optimization of the Ames RAMOS test allows for a reproducible high-throughput mutagenicity test2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Kira Kauffmann, Alexander Deitert, Julian Finklenburg, Julia Brendt, Andreas Schiwy, Henner Hollert, +1 more
21citations -
Optimization of a pre-metabolization procedure using rat liver S9 and cell-extracted S9 in the Ames fluctuation test2020 The Science of The Total Environment article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment
Ying Shao, Andreas Schiwy, Lisa Glauch, Luise Henneberger, Maria König, Marie Mühlenbrink, +5 more
31citations -
High-throughput screening of catalytically active inclusion bodies using laboratory automation and Bayesian optimization2024 Microbial Cell Factories article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Laura M. Helleckes, Kira Küsters, Rebecca Hamel, Ronja Saborowski, Jan Marienhagen, Wolfgang Wiechert, +1 more
16citations -
Cardinality optimization in constraint-based modelling: application to human metabolism2023 Bioinformatics article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Ronan M. T. Fleming, Hulda S. Haraldsdóttir, Phan Tu Vuong, Thomas Hankemeier, Ines Thiele
10citations -
Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) for Regulatory Testing—Protocol Optimization and Historical Control Data2025 Toxics article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Daphne van den Oetelaar, Marysia Tobor‐Kapłon, Mèlanie Reijnaers, Manon E. W. Beekhuijzen
12citations -
Mixed-Integer Optimization for Loopless Flux Distributions in Metabolic Networks2024 arXiv (Cornell University) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
João Dionísio, Tim Donkiewicz, Leon Eifler, Ambros Gleixner, Katrin Halbig, Ivo Hedtke, +9 more
89citations -
Immunohistochemical Detection of Estrogen Receptor-Beta (ERβ) with PPZ0506 Antibody in Murine Tissue: From Pitfalls to Optimization2022 Biomedicines article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Sarah K. Schröder, Carmen Gabriele Tag, Jan C. Kessel, Per Antonson, Ralf Weiskirchen
15citations -
Optimization of Targeted Lipid Nanoparticle for the Treatment of RUNX1::ETO Driven AML2024 Blood conference-abstract Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
L. Daniel Mata Casimiro, Manisha du Plessis, Dennis Unthan, Heyang Zhang, Matthias Barz, Raymond Michel Schiffelers, +1 more
2citations -
ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer2020 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Michael Rose, Sarah Bringezu, Laura Godfrey, David Fiedler, Nadine Therese Gaisa, Susanne Fuessel, +7 more
27citations -
Pilocarpine‐Induced Effects on Salivary Secretion as a Pharmacological Biomarker for Cholinergic Parasympathetic Activation2021 Clinical Pharmacology in Drug Development article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling
Nicoline Treijtel, Dorien Groenendaal‐van de Meent, Ingrid N. Michon, Cees Korstanje, John Meijer, Klaus Francke
5citations -
Bayesian experimental design for optimizing medium composition and biomass formation of tobacco BY-2 cell suspension cultures in stirred-tank bioreactors2025 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Plant tissue culture and regeneration Open access
Lars Leyendecker, Henrik Nausch, Christian Wergers, Dirk Scheffler, Robert Heinrich Schmitt
6citations -
Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery2026 ChemRxiv preprint Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Sean M. McKenna, Martin Šícho, Cas van der Horst, Jesse Maasland, Edith van der Nol, Andrius Bernatavicius, +3 more
0citations -
Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery2026 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Sean M. McKenna, Martin Šícho, Cas van der Horst, Jesse Maasland, Edith van der Nol, Gianluca Turco, +4 more
0citations -
Pseudomonas mRNA 2.0: Boosting Gene Expression Through Enhanced mRNA Stability and Translational Efficiency25citations
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Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management2023 Scientific Reports article Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Mafalda Antunes‐Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, +15 more
33citations -
Microbioreactor‐assisted cultivation workflows for time‐efficient phenotyping of protein producing Aspergillus niger in batch and fed‐batch mode2021 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Roman P. Jansen, Holger Morschett, Dennis Hasenklever, Matthias Moch, Wolfgang Wiechert, Marco Oldiges
4citations -
Optimizing interleukin-6 and 8 expression, clarification and purification in plant cell packs and plants for application in advanced therapy medicinal products and cellular agriculture11citations
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Integration of palladium-catalyzed C–N coupling into self-encoded libraries for accelerated hit discovery2026 RSC Chemical Biology article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Edith van der Nol, Zhenshuo Luo, Qingsong Gao, Nicola Haupt, Sebastian Böcker, Sebastian J. Pomplun
0citations -
HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions2025 Regulatory Toxicology and Pharmacology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Joel P. Bercu, Alejandra Trejo‐Martin, Connie L. Chen, Maik Schuler, Jennifer R. Cheung, Tetyana Cheairs, +29 more
15citations -
Dataset on temperature dependency of zebrafish early development2025 Scientific Data data-paper Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Katja Schröder, Caitlin Steindorf, Richard Ottermanns, Martina Roß‐Nickoll, Thomas Backhaus
6citations -
Dataset on Temperature Dependency of Zebrafish Early Development2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access
Katja Schröder, Knut Braun, Caitlin Steindorf, Richard Ottermanns, Martina Roß‐Nickoll, Thomas Backhaus
1citations