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Simulation and optimization of nutrient uptake and biomass formation using a multi-parameter Monod-type model of tobacco BY-2 cell suspension cultures in a stirred-tank bioreactor2023 Frontiers in Plant Science article Biochemistry, Genetics and Molecular Biology Plant tissue culture and regeneration Open access
Henrik Nausch, Marco Baldan, Katrin Teichert, Jannik Lutz, Carsten Claussen, Michael Bortz, +1 more
8citations -
A Quantitative Systems Pharmacology Perspective on the Importance of Parameter Identifiability2022 Bulletin of Mathematical Biology article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Anna Sher, Steven Niederer, Gary R. Mirams, Anna Kirpichnikova, Richard Allen, Pras Pathmanathan, +3 more
48citations -
A dual-parameter identification approach for data-based predictive modeling of hybrid gene regulatory network-growth kinetics in Pseudomonas putida mt-22020 Bioprocess and Biosystems Engineering article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis
Argyro Tsipa, Jake Alan Pitt, Julio R. Banga, Athanasios Mantalaris
4citations -
Enzyme kcat predictions and inter-method agreement analysis for the Escherichia coli iML1515 metabolic model2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Saleh Alwer, Hugues Escoffier, Chidi Egwu, Farid Zare, Jack McGoldrick, Ronan M. T. Fleming, +12 more
0citations -
Enzyme kcat predictions and inter-method agreement analysis for the Escherichia coli iML1515 metabolic model2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Saleh Alwer, Hugues Escoffier, Chidi Egwu, Farid Zare, Jack McGoldrick, Ronan M. T. Fleming, +12 more
0citations -
Incremental Parameter Estimation of Stochastic State-Based Models2021 IEEE World Symposium on Applied Machine Intelligence and Informatics (SAMI) conference-paper Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis cited by 1 patent
Anke Schmeink, Guido Dartmann, Lejla Begic Fazlic, Thomas R. Vollmer, Arne Peine, Lukas Märtin
3citations -
Performance and Robustness of Parameter Estimation from Phylogenetic Trees Using Neural Networks2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genomics and Phylogenetic Studies Open access
Tianjian Qin, Koen J. van Benthem, Luís Valente, Rampal S. Etienne
6citations -
A combined pH and temperature precipitation step facilitates the purification of tobacco‐derived recombinant proteins that are sensitive to extremes of either parameter28citations
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The clinical relevance of novel biomarkers as outcome parameter in adults with phenylketonuria2024 Journal of Inherited Metabolic Disease article Biochemistry, Genetics and Molecular Biology Metabolism and Genetic Disorders Open access
Annemiek M. J. van Wegberg, Janneke C. van der Weerd, Udo F. H. Engelke, Karlien L. M. Coene, Rianne Jahja, Stephan J. L. Bakker, +4 more
22citations -
Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the genome-scale2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
St. Elmo Wilken, Martin Beyß, Miroslav Kratochvíl, Alexa Grebel, Karen Methling, Anja Stefanski, +7 more
0citations -
PEtab-dev/libpetab-python: libpetab-python v0.9.02026 Zenodo (CERN European Organization for Nuclear Research) software Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Daniel Weindl, Yannik Schaelte, Dilan Pathirana, Polina Lakrisenko, Fabian Fröhlich, Simon Merkt, +15 more
0citations -
Data-based stochastic modeling reveals sources of activity bursts in single-cell TGF-β signaling2022 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Niklas Kolbe, Lorenz Hexemer, Lukas-Malte Bammert, Alexander Loewer, Mária Lukáčová-Medviďová, Stefan Legewie
9citations -
Design of experiments based optimization of pH and carbon dioxide to hydrogen ratio for enhanced acetate and biomass formation by Clostridium ljungdahlii0citations
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Microbioreactor‐assisted cultivation workflows for time‐efficient phenotyping of protein producing Aspergillus niger in batch and fed‐batch mode2021 Biotechnology Progress article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Roman P. Jansen, Holger Morschett, Dennis Hasenklever, Matthias Moch, Wolfgang Wiechert, Marco Oldiges
4citations -
Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome2020 Molecular Systems Biology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access cited by 4 patents
Ines Thiele, Swagatika Sahoo, Almut Heinken, Johannes Hertel, Laurent Heirendt, Maike Kathrin Aurich, +1 more
218citations -
Self-regulating microfluidic system for lipid nanoparticle production2025 Journal of Controlled Release article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Elena Reus, Johann Savinsky, Simon Wennemaring, Jonas Käsbach, Felix Kerkhoffs, Josef Kehrein, +5 more
8citations -
Bayesian experimental design for optimizing medium composition and biomass formation of tobacco BY-2 cell suspension cultures in stirred-tank bioreactors2025 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Plant tissue culture and regeneration Open access
Lars Leyendecker, Henrik Nausch, Christian Wergers, Dirk Scheffler, Robert Heinrich Schmitt
6citations -
Image Synthesis and Modified BlendMask Instance Segmentation for Automated Nanoparticle Phenotyping2023 IEEE Transactions on Medical Imaging article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques
Xiaoqin Tang, Lingpeng Lv, Shima Javanmardi, Yunfeng Wang, Jingchuan Fan, Fons J. Verbeek, +1 more
3citations -
Exploring Conformational Transitions of RNA Dimers via Machine Learning Potentials2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Leonardo Rafael Medrano Sandonas, Macarena Tolmos Nehme, Luis Fernando Cofas‐Vargas, Gustavo E. Olivos-Ramírez, Gianaurelio Cuniberti, Simón Poblete, +1 more
0citations
22 results