Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors

Molecular Cell, vol. 85, pp. 4633–4650.e11

Authors 19

1. Zeshi Li corresponding Aachen Human Genetics Department

   Leiden University · Utrecht University · Leiden University Medical Center · Delft University of Technology

   Affiliation as printed

   Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ, Delft, The Netherlands

   Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, The Netherlands

   Human Genetics department, Leiden University Medical Centre, 2333ZC Leiden, The Netherlands

   Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands; Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ Delft, the Netherlands. Electronic address: z.li@uu.nl

2. Bhagyashree S. Joshi

   Delft University of Technology

   Affiliation as printed

   Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ, Delft, The Netherlands

   Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ Delft, the Netherlands

3. Hongbo Yin Aachen

   Leiden University · Utrecht University · Leiden University Medical Center

   Affiliation as printed

   Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands; Division of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, the Netherlands

4. Ruud H. M. Wijdeven Aachen Department of Cell and Chemical Biology Oncode Institute

   Leiden University Medical Center · Oncode Institute · Vrije Universiteit Amsterdam · Amsterdam UMC Location Vrije Universiteit Amsterdam

   Affiliation as printed

   Department of Cell and Chemical Biology, Oncode Institute, Leiden University Medical Center, 2333 ZA Leiden, Zuid-Holland, the Netherlands

   Department of Functional Genomics, Center for Neurogenomics and Cognitive Research (CNCR), Vrije Universiteit Medical Center, 1007 MB Amsterdam, Noord-Holland, the Netherlands

5. Rue A. Koç Aachen

   Leiden University · Utrecht University · Leiden University Medical Center

   Affiliation as printed

   Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands; Division of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, the Netherlands

6. Dick W. Zijlmans

   Radboud University Nijmegen · Radboud Institute for Molecular Life Sciences

   Affiliation as printed

   Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Oncode Institute, Radboud University Nijmegen, Nijmegen 6525 GA, the Netherlands

7. Abhijeet Pataskar

   Radboud University Nijmegen · Radboud Institute for Molecular Life Sciences

   Affiliation as printed

   Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Oncode Institute, Radboud University Nijmegen, Nijmegen 6525 GA, the Netherlands

8. Irene Santos‐Barriopedro Aachen Sequencing Analysis Support Core Department of Biomedical Data Sciences

   Leiden University · Radboud University Nijmegen · Leiden University Medical Center · Radboud Institute for Molecular Life Sciences · Oncode Institute

   Affiliation as printed

   Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands

   Sequencing Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, the Netherlands

9. Hailiang Mei Aachen

   Leiden University · Utrecht University · Leiden University Medical Center

   Affiliation as printed

   Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands; Division of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, the Netherlands

10. Wei Wu Aachen Human Genetics Department

    Leiden University · Leiden University Medical Center

    Affiliation as printed

    Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands

11. Milad Shademan Aachen Human Genetics Department

    Leiden University · Utrecht University · Leiden University Medical Center

    Affiliation as printed

    Human Genetics department, Leiden University Medical Centre, 2333ZC Leiden, The Netherlands

    Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands; Division of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrecht, the Netherlands

12. Filip M. Zawisza Aachen Department of Cell and Chemical Biology

    Leiden University Medical Center

    Affiliation as printed

    Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands

13. Eric Bos Aachen Department of Cell and Chemical Biology

    University of Georgia · Leiden University Medical Center

    Affiliation as printed

    Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, The Netherlands

    Complex Carbohydrate Research Center, University of Georgia, Athens, GA 30602, USA

14. Pradeep Chopra

    University Medical Center Utrecht · Oncode Institute · Delft University of Technology

    Affiliation as printed

    Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ Delft, the Netherlands; Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands

15. Marvin E. Tanenbaum Aachen

    Utrecht University · Leiden University Medical Center · University Medical Center Utrecht · University of Bristol · Oncode Institute · Hubrecht Institute for Developmental Biology and Stem Cell Research · Delft University of Technology

    Affiliation as printed

    Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ, Delft, The Netherlands

    Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands

    Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK

16. Thomas Harry Sharp

    Radboud University Nijmegen · The Netherlands Cancer Institute · University of Bristol · Radboud Institute for Molecular Life Sciences

    Affiliation as printed

    School of Biochemistry, University of Bristol, Bristol BS8 1TD, U.K

    Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Oncode Institute, Radboud University Nijmegen, Nijmegen 6525 GA, the Netherlands; Division of Molecular Genetics, Netherlands Cancer Institute, Amsterdam 1066 CX, the Netherlands

17. Michiel Vermeulen Aachen Human Genetics Department

    Leiden University · Radboud University Nijmegen · Leiden University Medical Center · The Netherlands Cancer Institute · Radboud Institute for Molecular Life Sciences · Oncode Institute

    Affiliation as printed

    Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, Nijmegen, The Netherlands

    Division of Molecular Genetics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    Human Genetics Department, Leiden University Medical Centre, 2333 ZC Leiden, the Netherlands. Electronic address: v.raz@lumc.nl

18. Vered Raz corresponding Aachen Human Genetics Department

    Leiden University · Ewha Womans University · Leiden University Medical Center · Delft University of Technology

    Affiliation as printed

    Human Genetics department, Leiden University Medical Centre, 2333ZC Leiden, The Netherlands

    Department of BioNanoScience, Kavli Institute of Nanoscience Delft, Delft University of Technology, 2629 HZ Delft, the Netherlands; Department of Physics, Ewha Woman's University, Seoul 03760, Republic of Korea. Electronic address: c.joo@tudelft.nl

19. Chirlmin Joo corresponding Aachen Human Genetics Department

    Leiden University · Ewha Womans University · Leiden University Medical Center

    Affiliation as printed

    Department of Physics, Ewha Womans University, Seoul 03760, Republic of Korea

    Human Genetics department, Leiden University Medical Centre, 2333ZC Leiden, The Netherlands