Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

• CRISPR activation reveals SOX5/6/9 as key transcriptional regulators directing iPSC-derived cells toward a notochordal lineage

  2026 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access

  0

  citations
• Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors

  2025 Molecular Cell article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access cited by 1 patent

  22

  citations
• SMAD3 and p300 complex scaffolding by long non-coding RNA LIMD1-AS1 promotes TGF-β-induced breast cancer cell plasticity

  2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access

  5

  citations
• Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers

  2025 Nature Genetics article Biochemistry, Genetics and Molecular Biology Cancer, Lipids, and Metabolism Open access

  5

  citations
• Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access

  9

  citations
• CRISPR Activation Interrogation of iPSC-Based Notochordal Lineage Reveals the Functional Significance of the SOX Genes in Disc Regeneration

  2025 SSRN Electronic Journal preprint Medicine Spine and Intervertebral Disc Pathology Open access

  0

  citations
• Isolation and tracing of matrix-producing notochordal and chondrocyte cells using ACAN-2A-mScarlet reporter human iPSC lines

  2024 Science Advances article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access

  8

  citations
• Cell-Surface RNA Forms Ternary Complex with RNA-Binding Proteins and Heparan Sulfate to Recruit Immune Receptors

  2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access

  4

  citations
• Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal cancers

  2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Cancer, Lipids, and Metabolism Open access

  0

  citations
• The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent

  2023 Cell Reports article Immunology and Microbiology Immune Cell Function and Interaction Open access

  20

  citations
• A genome-wide CRISPR/Cas phenotypic screen for modulators of DUX4 cytotoxicity reveals screen complications

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access

  2

  citations
• Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes

  2020 Scientific Reports article Medicine Chemotherapy-induced cardiotoxicity and mitigation Open access

  49

  citations

12 results