Community-driven ELIXIR activities in single-cell omics
F1000Research, vol. 11, pp. 869
Abstract
Single-cell omics (SCO) has revolutionized the way and the level of resolution by which life science research is conducted, not only impacting our understanding of fundamental cell biology but also providing novel solutions in cutting-edge medical research. The rapid development of single-cell technologies has been accompanied by the active development of data analysis methods, resulting in a plethora of new analysis tools and strategies every year. Such a rapid development of SCO methods and tools poses several challenges in standardization, benchmarking, computational resources and training. These challenges are in line with the activities of ELIXIR, the European coordinated infrastructure for life science data. Here, we describe the current landscape of and the main challenges in SCO data, and propose the creation of the ELIXIR SCO Community, to coordinate the efforts in order to best serve SCO researchers in Europe and beyond. The Community will build on top of national experiences and pave the way towards integrated long-term solutions for SCO research.
Authors 27
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Stockholm University · Science for Life Laboratory · National Bioinformatics Infrastructure Sweden
Affiliation as printed
Science for Life Laboratory, Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Stockholm University, Solna, Sweden
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Leiden University Medical Center · Delft University of Technology
Affiliation as printed
Department of Human Genetics, The Netherlands & Delft Bioinformatics Lab, Leiden University Medical Center, Delft University of Technology, Leiden, Delft, The Netherlands
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Affiliation as printed
Bioinformatics and Genomics unit, Dept. Molecular Biotechnology and Health Science, University of Torino, Torino, Italy
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SIB Swiss Institute of Bioinformatics
Affiliation as printed
SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland
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Barcelona Supercomputing Center
Affiliation as printed
Barcelona Supercomputing Center, Barcelona, Spain
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Barcelona Supercomputing Center
Affiliation as printed
Barcelona Supercomputing Center, Barcelona, Spain
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SIB Swiss Institute of Bioinformatics · Friedrich Miescher Institute
Affiliation as printed
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland
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European Bioinformatics Institute
Affiliation as printed
European Bioinformatics Institute, Hinxton, UK
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Affiliation as printed
Division of Infection and Immunity, School of Medicine, Cardiff University, Wales, UK
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Affiliation as printed
Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany
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Affiliation as printed
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
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European Bioinformatics Institute
Affiliation as printed
European Bioinformatics Institute, Hinxton, UK
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Affiliation as printed
Institute of Biochemistry and Molecular Genetics, Faculty of Medicine,, University of Ljubljana, Ljubljana, Slovenia
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Affiliation as printed
Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany
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Affiliation as printed
Earlham Institute, Norwich, UK
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University of Luxembourg · Luxembourg Centre for Systems Biomedicine
Affiliation as printed
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Luxembourg, Luxembourg
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Barcelona Supercomputing Center
Affiliation as printed
Barcelona Supercomputing Center, Barcelona, Spain
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Affiliation as printed
Institute of Biochemistry and Molecular Genetics, Faculty of Medicine,, University of Ljubljana, Ljubljana, Slovenia
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Affiliation as printed
Bioinformatics and Genomics unit, Dept. Molecular Biotechnology and Health Science, University of Torino, Torino, Italy
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Affiliation as printed
Bioinformatics and Genomics unit, Dept. Molecular Biotechnology and Health Science, University of Torino, Torino, Italy
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Affiliation as printed
Institute of Biochemistry and Molecular Genetics, Faculty of Medicine,, University of Ljubljana, Ljubljana, Slovenia
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Vlaams Instituut voor Biotechnologie
Affiliation as printed
VIB Bioinformatics Core, Ghent, Belgium
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Affiliation as printed
Institute of Biochemistry and Molecular Genetics, Faculty of Medicine,, University of Ljubljana, Ljubljana, Slovenia
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Stockholm University · Science for Life Laboratory · National Bioinformatics Infrastructure Sweden
Affiliation as printed
Science for Life Laboratory, Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Stockholm University, Solna, Sweden
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Affiliation as printed
ELIXIR Hub, Wellcome Genome Campus, Hinxton, UK
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Berlin Institute of Health at Charité - Universitätsmedizin Berlin
Affiliation as printed
Digital Health Center, Berlin Institute of Health at Charité, Universitätsmedizin Berlin, Berlin, Germany
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CSC - IT Center for Science (Finland)
Affiliation as printed
CSC – IT center for science, Espoo, Finland
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