Proteome Regulation Patterns Determine Escherichia coli Wild-Type and Mutant Phenotypes

mSystems, vol. 6

Abstract

tools, the PAM and related simulation approaches will foster the use of a model-driven metabolic research. Applications range from the investigation of mechanisms of microbial evolution to the determination of optimal strain design strategies in metabolic engineering, thus supporting basic scientists and engineers alike.

Authors 3

1. Tobias B. Alter Aachen Institute of Applied Microbiology

   RWTH Aachen University

   Affiliation as printed

   Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Aachen, Germany

2. Lars M. Blank Aachen Institute of Applied Microbiology

   RWTH Aachen University

   Affiliation as printed

   Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Aachen, Germany

3. Birgitta E. Ebert corresponding Aachen Institute of Applied Microbiology

   RWTH Aachen University · The University of Queensland

   Affiliation as printed

   Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Australia

   Institute of Applied Microbiology (iAMB), Aachen Biology and Biotechnology (ABBt), RWTH Aachen University, Aachen, Germany