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Fungal metabarcoding data integration framework for the MycoDiversity DataBase (MDDB)

Berichte aus der medizinischen Informatik und Bioinformatik/Journal of integrative bioinformatics, vol. 17

Abstract

Fungi have crucial roles in ecosystems, and are important associates for many organisms. They are adapted to a wide variety of habitats, however their global distribution and diversity remains poorly documented. The exponential growth of DNA barcode information retrieved from the environment is assisting considerably the traditional ways for unraveling fungal diversity and detection. The raw DNA data in association to environmental descriptors of metabarcoding studies are made available in public sequence read archives. While this is potentially a valuable source of information for the investigation of Fungi across diverse environmental conditions, the annotation used to describe environment is heterogenous. Moreover, a uniform processing pipeline still needs to be applied to the available raw DNA data. Hence, a comprehensive framework to analyses these data in a large context is still lacking. We introduce the MycoDiversity DataBase, a database which includes public fungal metabarcoding data of environmental samples for the study of biodiversity patterns of Fungi. The framework we propose will contribute to our understanding of fungal biodiversity and aims to become a valuable source for large-scale analyses of patterns in space and time, in addition to assisting evolutionary and ecological research on Fungi.

Authors 10

  1. Leiden University · Naturalis Biodiversity Center

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

    Understanding Evolution , Naturalis Biodiversity Center , Leiden , The Netherlands

  2. Leiden University

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

  3. Naturalis Biodiversity Center

    Affiliation as printed

    Understanding Evolution , Naturalis Biodiversity Center , Leiden , The Netherlands

  4. Naturalis Biodiversity Center

    Affiliation as printed

    Understanding Evolution , Naturalis Biodiversity Center , Leiden , The Netherlands

  5. Naturalis Biodiversity Center

    Affiliation as printed

    Understanding Evolution , Naturalis Biodiversity Center , Leiden , The Netherlands

  6. Leiden University

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

  7. Leiden University

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

  8. Leiden University

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

  9. Naturalis Biodiversity Center · University of Amsterdam

    Affiliation as printed

    Department of Evolutionary and Population Biology , Institute for Biodiversity and Ecosystem Dynamics , University of Amsterdam , Amsterdam , The Netherlands

    Understanding Evolution , Naturalis Biodiversity Center , Leiden , The Netherlands

  10. Leiden University

    Affiliation as printed

    Leiden Institute of Advanced Computer Science (LIACS) , Leiden University , Leiden , The Netherlands

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References 110