Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment

• Problem formulation and conceptual framework for landscape-based environmental risk assessment of pesticides

  2026 Environment International article Environmental Science Pesticide and Herbicide Environmental Studies Open access

  0

  citations
• A transcriptomics-driven quantitative adverse outcome pathway network model for gentamicin-induced nephrotoxicity

  2026 Computational Toxicology article Medicine Acute Kidney Injury Research Open access

  1

  citations
• Quantitative adverse outcome pathway modeling of cisplatin-induced nephrotoxicity: developing in vitro and in vivo models for predictive extrapolation

  2026 Toxicological Sciences article Veterinary Animal testing and alternatives Open access

  1

  citations
• Deciphering the quantitative relationship between NRF2 and SRXN1 through semi-mechanistic computational modeling

  2025 Toxicology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access

  1

  citations
• Mathematical modelling reveals compound-specific stress pathway activity

  2025 Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access

  4

  citations
• Towards a quantitative adverse outcome pathway for liver carcinogenesis: From proliferation to prediction

  2025 Computational Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access

  1

  citations
• Interdependency of estradiol-mediated ERα activation and subsequent PR and GREB1 induction to control cell cycle progression

  2024 Heliyon article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access

  3

  citations
• Systems toxicology to advance human and environmental hazard assessment: A roadmap for advanced materials

  2022 Nano Today article Environmental Science Environmental Toxicology and Ecotoxicology Open access

  25

  citations
• Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations

  2022 Environmental Research article Veterinary Animal testing and alternatives Open access

  102

  citations
• A quantitative AOP of mitochondrial toxicity based on data from three cell lines

  2022 Toxicology in Vitro article Veterinary Animal testing and alternatives Open access

  23

  citations
• The Eco-Exposome Concept: Supporting an Integrated Assessment of Mixtures of Environmental Chemicals

  2021 Environmental Toxicology and Chemistry article Environmental Science Environmental Toxicology and Ecotoxicology Open access

  55

  citations

11 results